Kidney Week 2024 | 北京大学第一医院研究成果繁星璀璨

文摘   健康   2024-10-26 09:16   北京  


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美国太平洋时间10月23~24日,2024年美国肾脏病学会年会—美国肾脏周(Kidney Week 2024)在圣迭戈盛大举行。今年,北京大学第一医院有二十多项研究成果入选大会,其中5项研究是北京大学第一医院研究团队参与的多中心研究,21项是作为第一作者单位的研究,让我们来看看都有哪些吧!




北京大学第一医院作为第一作者单位的研究


  • Correlation between PKD1 Mutation Type and Height-Adjusted Total Kidney Volume in Chinese Patients with ADPKD: Genotype-Phenotype Analysis

中国常染色体显性多囊肾病(ADPKD)患者中PKD1突变类型与身高调整后的肾脏总体积之间的相关性:基因型-表型分析
[TH-PO477] 第一作者:Liu Zhiying
October 24, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • A Boy with Steroid-Resistant Nephrotic Syndrome and Cortical Blindness

一例患有激素抵抗型肾病综合征和皮质盲的男孩病例

[TH-PO497] 第一作者:Wang Fang
October 24, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Genome-Wide Survival Study Identifies Variants Associated with Disease Progression in IgA Nephropathy

全基因组生存研究确定了与IgA肾病疾病进展相关的突变

[TH-PO529] 第一作者:Xu Linlin
October 24, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Type II Glycoengineered Anti-CD20 Antibody MIL62 or Cyclosporine in Chinese Primary Membranous Nephropathy: A Multicenter, Randomized, Open-Label Phase 1b/2 Trial

Ⅱ型糖工程化抗CD20抗体MIL62或环孢素在中国原发性膜性肾病中的应用:一项多中心、随机、开放性Ⅰb/Ⅱ期试验
[TH-PO601] 第一作者:崔昭
October 24, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Complement Activation Products in Kidneys of Patients with Primary Focal Segmental Glomerulosclerosis

原发性局灶节段性肾小球硬化症患者肾脏中的补体活化产物

[TH-PO618] 第一作者:Gong Xiaojie
October 24, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Phenome-Wide Mendelian Randomization Analysis of the Plasma Proteins, Immune Cell Types, and Immune Cell Traits in IgAN

IgA肾病中血浆蛋白、免疫细胞类型及免疫细胞特征的表型全基因组孟德尔随机化分析
[FR-OR42] 第一作者:You Ruilian
October 25, 2024 | 05:20 PM - 05:30 PM
Location: Room 1, Convention Center

  • Ambient Air Pollutant Mixture, Sleep Pattern, and Incident CKD: Results from a Prospective Cohort Study

环境空气污染物混合物、睡眠模式与CKD发病的关系:一项前瞻性队列研究的结果
[FR-PO1088]第一作者:Zhang Feifei
October 25, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Comparative Effectiveness of Roxadustat vs. Erythropoiesis-Stimulating Agents (ESAs) on Anemia and Kidney Outcomes among Patients with CKD: A Retrospective Cohort Study

罗沙司他与促红细胞生成素(ESA)对CKD患者贫血和肾脏结局影响的比较效果研究:一项回顾性队列研究

[FR-PO1161] 第一作者:Wang Jinwei
October 25, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • TOMM7 Alleviates Diabetic Kidney Disease by Regulating PINK1/Parkin-Mediated Mitophagy via Intracellular Redistribution of PLA2G6

TOMM7通过调节PINK1/Parkin介导的线粒体自噬(经由PLA2G6的细胞内再分布)来减轻糖尿病肾病
[FR-PO277]第一作者:Wang Yihui
October 25, 2024 | 10:00 AM - 12:00 PM
Location: Exhibit Hall, Convention Center

  • Supporting Self-Management of Kidney Health in Diabetic Patients via a Novel Digital Health Intervention: Protocol for a Prospective Interventional Study

通过新型数字健康干预支持糖尿病患者肾脏健康的自我管理:一项前瞻性干预研究方案
[FR-PO340] 第一作者:Wu Jingyi
October 25, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • The Difference between Cystatin C- and Creatinine-Based Estimated Glomerular Filtration Rate and Risk of Peripheral Artery Disease

基于胱抑素C和肌酐估算的肾小球滤过率差异以及外周动脉疾病风险
[FR-PO342]第一作者:He Daijun
October 25, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Glomerular Filtration Rate by Differing Measures and Prediction Utility of Peripheral Artery Disease

不同测量方法得出的肾小球滤过率以及外周动脉疾病的预测效用

[FR-PO345] 第一作者:Li Chenglong
October 25, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Health Services Accessibility and Clinical Outcomes in Peritoneal Dialysis: Findings from the PDTAP Study

腹膜透析的医疗服务可及性与临床结局:来自PDTAP研究的结果
[FR-PO450]第一作者:Wang Qinghua
October 25, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Relationship between Exercise and the Occurrence of Abdominal Wall Complications among Patients on Peritoneal Dialysis

运动与腹膜透析患者腹壁并发症发生之间的关系

[FR-PO459]第一作者:Li Xinqiu
October 25, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Founder Effect for the APOE Tokyo-Maebashi Variant in the Northern Chinese Population

中国北方人群中APOE Tokyo-Maebashi突变的奠基者效应
[FR-PO679]第一作者:Li Mengshi
October 25, 2024 | 10:00 AM - 12:00 PM
Location: Exhibit Hall, Convention Center

  • The Role of von Willebrand Factor (vWF) in the Pathogenesis of C3 Glomerulopathy (C3G)

血管性血友病因子(vWF)在C3肾小球病(C3G)发病机制中的作用
[FR-PO808]第一作者:Hua Zixin
October 25, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Perlecan Is a Novel Target of Autoantibodies in Anti-glomerular Basement Membrane Disease

Perlecan是抗肾小球基底膜疾病中自身抗体的新靶点
[FR-PO832]第一作者:Kuang Huang
October 25, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Urinary Proteomics Identify Biomarkers for Predicting Complete Remission of Proteinuria in Pediatric IgA Nephropathy

尿蛋白质组学鉴定用于预测儿童IgA肾病蛋白尿完全缓解的生物标志物
[FR-PO903] 第一作者:Zhou Jianmei
October 25, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Development of Risk-Prediction Tool for Peritoneal Dialysis-Associated Peritonitis and External Validation in the PDTAP Cohort

腹膜透析相关性腹膜炎风险预测工具的开发及在PDTAP队列中的外部验证

[SA-PO460] 第一作者:Qiao Yumeng
October 26, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Protective Effect of Ambrisentan on Proteinuria in Patients with Alport Syndrome

安立生坦对Alport综合征患者蛋白尿的保护作用
[SA-PO641]第一作者:Song Zhuoran
October 26, 2024 | 10:00 AM - 10:00 AM
Location: Exhibit Hall, Convention Center

  • Atypical ADPKD Due to Complex Genotypes of Both PKD1 and HNF1B Pathogenic Variants: An Educational Case Report

因PKD1和HNF1B致病性变异体复杂基因型导致的非典型常染色体显性多囊肾病:一例有教育意义的病例报告
[PUB285] 第一作者:Li Mengshi
Publication Only



北京大学第一医院参与的多中心研究


  • NeflgArd Open-Label Extension: Efficacy and Safety of Nefecon in Patients with IgAN Who Completed the 2-Year Phase 3 Trial

NeflgArd开放性扩展研究:在完成2年Ⅲ期试验的IgA肾病(IgAN)患者中评估Nefecon的疗效和安全性
[FR-OR56] 第一作者:Lafayette, Richard A
October 25, 2024 | 04:40 PM - 04:50 PM
Location: Room 6D, Convention Center

  • ALIGN Subgroup Analyses: Clinically Meaningful Urinary Protein-to-Creatinine Ratio Reductions across Subgroups

ALIGN亚组分析:各亚组中具有临床意义的尿蛋白/肌酐比值降低
[FR-OR62] 第一作者:Hiddo Jan L Heerspink
October 25, 2024 | 05:30 PM - 05:40 PM
Location: Room 6D, Convention Center

  • Zanubrutinib for the Treatment of Primary Membranous Nephropathy (PMN): Results of a Single-Arm Feasibility Study

Zanubrutinib用于治疗原发性膜性肾病(PMN):单臂可行性研究结果

[TH-PO1204]第一作者:Lafayette, Richard A., Stanford University Medical Center, Stanford,California, United States;
LAST AUTHOR:赵明辉(北京大学第一医院)
October 24, 2024 | 10:00 AM - 12:00 PM
Location: Exhibit Hall, Convention Center

  • SHR6508, a Calcium-Sensing Receptor Agonist, in Patients on Hemodialysis Who Have Secondary Hyperparathyroidism: A Phase 2 Trial

钙敏感受体激动剂SHR6508用于血液透析合并继发性甲状旁腺功能亢进患者的治疗:一项Ⅱ期临床试验
[TH-PO134]第一作者:余学清(广东省人民医院);第四作者:陈育青(北京大学第一医院)
October 24, 2024 | 10:00 AM - 12:00 PM
Location: Exhibit Hall, Convention Center

  • ORIGIN 3: Pivotal Ph3 Study Evaluating Effect of Atacicept vs. Placebo on Proteinuria and Kidney Function Preservation in IgAN

ORIGIN 3:评估Atacicept与安慰剂相比对IgAN患者蛋白尿和肾功能保护的影响的关键性Ⅲ期临床研究
[INFO09-FR]第一作者:Lafayette, Richard A.
October 25, 2024 | 10:00 AM - 12:00 PM
Location: Exhibit Hall, Convention Center






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