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痤疮疗效改善国际联盟（The Global Alliance to Improve Outcomes in Acne ）是一个由皮肤科医生组成的国际组织，其成员均为痤疮研究治疗领域的顶级专家。
复旦大学附属华山医院皮肤科项蕾红教授也参与其中，与全球各国专家一同致力于痤疮研究与教育，并于近期推出了痤疮临床治疗国际共识。
该共识集结了国际专家的意见与经验，聚焦于治疗理念、患者个体以及具体场景下适用疗法的判断依据。共识通过德尔菲法总结出了有效应对痤疮的核心原则，旨在帮助指导皮肤科医生掌握有效的痤疮治疗策略，并能够应用于实际治疗。
维甲酸在痤疮治疗过程中具有重要作用，对于多数炎症性和/或粉刺型痤疮患者而言，外用维甲酸加过氧化苯甲酰是首选疗法。
Retinoids have an essential role in treatment of acne. For the majority of patients with inflammatory and/or comedonal acne, a topical retinoid plus BPO is first line therapy.
抗生素在痤疮治疗中的作用有变化，局部或系统性应用抗生素均不能作为单一疗法治疗痤疮。
The role of antibiotics in acne therapy has changed. Neither topical nor systemic antibiotics should be used as monotherapy for acne treatment.
口服异维甲酸是治疗严重痤疮（囊肿/聚合性痤疮）的首选疗法。
Oral isotretinoin should be first-line therapy for very severe (cystic/conglobate) acne.
口服异维甲酸治疗需持续至痤疮完全清除，维持缓解总剂量还需进一步研究确认。
Oral isotretinoin therapy should proceed until full clearance of acne. Additional studies are needed to define a total cumulative dose that maintains remission.
口服异维甲酸后痤疮恶化情况可以通过初始治疗时低剂量服用来缓解。
Acne flare with oral isotretinoin can be minimized by initiating therapy with a low dose.
多数痤疮患者宜单独外用维甲酸或联合过氧化苯甲酰以维持治疗，外用抗生素不宜作为痤疮维持疗法。
Most patients with acne should receive maintenance therapy with a topical retinoid with or without BPO. Topical antibiotics should not be used as acne maintenance therapy.
20%壬二酸霜或15%凝胶能有效治疗孕期女性痤疮以及痤疮伴PIH患者。
Azelaic acid cream 20% or gel 15% is a useful acne treatment in pregnant women and patients with acne and PIH.
目前，设备类包括激光、IPL、光动力治疗不宜作为炎症性痤疮首选疗法。
At present, devices including laser, intense pulsed light (IPL), and photodynamic therapy (PDT) should not be considered first line treatment for inflammatory acne.
少数25岁或25岁以上女性痤疮病损仅位于下面部，单独外用维甲酸或联合过氧化苯甲酰对于治疗成年人痤疮非常重要。
A minority of women 25 years or older have acne lesions localized only to the lower face. Topical retinoids with or without BPO are important components in therapy of adult acne.
早期有效治疗对于降低潜在痤疮瘢痕风险至关重要。
Early and effective treatment is important to minimize potential risk for acne scarring.
Source: PRACTICAL MANAGEMENT OF ACNE FOR CLINICIANS An International Consensus from the Global Alliance to Improve Outcomes in Acne, Journal of the American Academy of Dermatology, first online article
