内容简介
本研究论文提出了一种可用于各种柔性基材的新型激光雕刻表面粗糙化策略。该加工方法可构建在汗液填充前后显示出明显的结构反射率变化的微流道。通过利用这些独特的光学特性改变，我们开发了一种完全激光雕刻的微流体装置，用于裸眼量化汗液流失。该汗液流失传感器的体积分辨率为0.5 μL，总体积容量为11 μL，并且可以个性化定制以满足不同的性能需求。基于此，本文报道了一种无串扰双模态汗液微流体系统，该系统集成了 Ag/AgCl 氯离子传感器及其匹配的无线测量柔性印刷电路板。该集成系统能够实时监测汗液流失比色信号和离子浓度电压信号，且这种双模态读数不会产生串扰。最后，我们通过体表佩戴运动排汗研究，揭示了人体汗液氯离子浓度与出汗率之间的正相关性，展示了这种微流控汗液流失传感器及其集成系统在运动医学中的潜在用途价值。
引用本文（点击最下方阅读原文可下载PDF）
Zhong B, Xu H, Qin X, et al., 2024. A crosstalk-free dual-mode sweat sensing system for naked-eye sweat loss quantification via changes in structural reflectance. Bio-des Manuf 7(4):428–438. https://doi.org/10.1007/s42242-024-00294-2
文章导读
图1 系统的运行原理和结构设计
图2 用于汗液流失检测的微流控模块性能表征
图3 用于氯离子浓度检测的电化学模块性能表征及其集成系统的无串扰双模态测量
图4 系统的在体汗液监测
参考文献
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Bio-Design and Manufacturing（中文名《生物设计与制造》），简称BDM，是浙江大学主办的专业英文双月刊，主编杨华勇院士、崔占峰院士，2018年新创，2019年被SCI-E等库检索，2023年起改为双月刊，年末升入《2023年中国科学院文献情报中心期刊分区表》医学一区，2024年公布的最新影响因子为8.1，位列JCR的Q1区，13/122。
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