《信号转导与靶向治疗》(Signal Transduction and Targeted Therapy,以下简称STTT)是信号转导与靶向治疗领域具有国际影响力和号召力的高水平学术期刊。期刊涵盖的学科包括基础医学、临床医学、分子生物学、细胞生物学、药理学、药物化学和生物信息学等,旨在从多学科交叉角度发表肿瘤、自身免疫病等人类疾病的分子机理、信号转导以及相关靶向治疗的最新研究进展。STTT目前已被国内外多个数据库收录,包括Science Citation Index Expanded(SCIE)(影响因子39.3),Journal Citation Reports/Science Edition,BIOSIS previews,Directory of Open Access Journals (DOAJ),MEDLINE,PubMed Central(PMC),Scopus和中国科学引文数据库(Chinese Science Citation Database,CSCD)核心库、中国科技核心期刊数据库、世界期刊影响力指数(WJCI)报告等。
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Chi, H., Zhao, SQ., Chen, RY. et al. Rapid development of double-hit mRNA antibody cocktail against orthopoxviruses. Sig Transduct Target Ther 9, 69 (2024). https://doi.org/10.1038/s41392-024-01766-8
原文链接:
https://www.nature.com/articles/s41392-024-01766-8
军事科学院军事医学研究院秦成峰/邓永强团队于2024年3月27日在Signal Transduction and Targeted Therapy 发表封面文章“Rapid development of double-hit mRNA antibody cocktail against orthopoxviruses”。研究团队利用建立的纳米脂球颗粒(LNP)-mRNA技术平台,成功开发了可对正痘病毒感染提供完全保护的mRNA抗体鸡尾酒。(点击下方图片可查看封面文章详细解读)
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Yang, Z., Gao, J., Zheng, J. et al. Efficacy and safety of PD-1 blockade plus long-course chemoradiotherapy in locally advanced rectal cancer (NECTAR): a multi-center phase 2 study. Sig Transduct Target Ther 9, 56 (2024). https://doi.org/10.1038/s41392-024-01762-y
原文链接:
https://www.nature.com/articles/s41392-024-01762-y
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Ma, L., Chen, C., Zhao, C. et al. Targeting carnitine palmitoyl transferase 1A (CPT1A) induces ferroptosis and synergizes with immunotherapy in lung cancer. Sig Transduct Target Ther 9, 64 (2024). https://doi.org/10.1038/s41392-024-01772-w
原文链接:
https://www.nature.com/articles/s41392-024-01772-w
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Xiong, J., Cheng, S., Gao, X. et al. Anti-metabolic agent pegaspargase plus PD-1 antibody sintilimab for first-line treatment in advanced natural killer T cell lymphoma. Sig Transduct Target Ther 9, 62 (2024). https://doi.org/10.1038/s41392-024-01782-8
原文链接:
https://www.nature.com/articles/s41392-024-01782-8
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Fang, Z., Shen, G., Wang, Y. et al. Elevated Kallistatin promotes the occurrence and progression of non-alcoholic fatty liver disease. Sig Transduct Target Ther 9, 66 (2024). https://doi.org/10.1038/s41392-024-01781-9
原文链接:
https://www.nature.com/articles/s41392-024-01781-9
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