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学术 2024-07-25 17:31 湖北

中国病毒学英文版IF:4.3

公众号ID：virologica

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Cover Story

Foot-and-mouth disease (FMD) is a highly contagious disease caused by the FMD virus (FMDV). Although the cell receptor for FMDV has been identified, the specific mechanism of FMDV internalization after infection remains unknown. In this issue, Zhang et al. demonstrated that kinesin family member 5B (KIF5B) plays a crucial role in FMDV internalization. KIF5B directly interacts with VP1 to facilitate FMDV internalization by regulating clathrin uncoating. Further evidence indicated that KIF5B also facilitates the transport of viral particles to early and late endosomes during the early stages of FMDV infection. The cover image depicts FMDV (red) hijacks host cell protein KIF5B (yellow) to invade the host cell and is then transported by KIF5B to the endosomes for uncoating, releasing RNA for reproduction. Subsequently, FMDV wrests cell resources (blue) within the host cell to complete its own replication, assembly, and release processes, thus completing its life cycle.

(Kindly designed and provided by Wei Zhang and Prof. Haixue Zheng). See page 378–389 for details.

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整期直达：

https://www.sciencedirect.com/journal/virologica-sinica/vol/39/issue/3

1. 联合删除多功能MGF505-7R和H240R基因产生的非洲猪瘟减毒活疫苗候选株安全有效

作者：

翁长江，黄丽，叶光强

Joint deletion of multifunctional MGF505-7R and H240R genes generates a safe and effective African swine fever virus attenuated live vaccine candidate

Virol Sin. 2024 Jun.; 39(3): 355-357.

‍https://doi.org/10.1016/j.virs.2024.04.007‍

2. 2021–2022年中国Clade 2.3.4.4b分支H5亚型禽流感病毒的演化动态和致病性差异分析

作者：

林思茹，陈俊宏，李珂，柳洋，付思源，谢淑敏，查爱敏，信爱国，韩心雨，史玉婷，徐玲玉，廖明，贾伟新

Evolutionary dynamics and comparative pathogenicity of clade 2.3.4.4b H5 subtype avian influenza viruses, China, 2021–2022

‍Virol Sin. 2024 Jun.; 39(3): 358-368.

https://doi.org/10.1016/j.virs.2024.04.004‍

3. 基于血清流行的巴基斯坦健康人群感染虫媒病毒的风险

作者：

陈声耀，Muhammad Saqib，Hafiz sajid Khan，白源，Usman Ali Ashfaq，Muhammad Khalid Mansoor，阿布力米提·莫明，刘静，周敏， Saifullah Khan Niazi，吴巧丽，Awais-Ur-Rahman Sial，唐霜， Muhammad Hassan Sarfraz，Aneela Javed，Sumreen Hayat，Mohsin Khurshid，Iahtasham Khan，Muhammad Ammar Athar，Zeeshan Taj, 张波，邓菲，Ali Zohaib，沈姝

Risk of infection with arboviruses in a healthy population in Pakistan based on seroprevalence

Virol Sin. 2024 Jun.; 39(3): 369-377.

https://doi.org/10.1016/j.virs.2024.04.001‍

4. KIF5B介导FMDV内化促进病毒复制

作者：

张伟，杨帆，杨洋，曹伟军，邵文华，王家丽，黄梦瑶，陈志彤，赵晓义，李伟伟，朱紫祥，郑海学

KIF5B-mediated internalization of FMDV promotes virus infection

Virol Sin. 2024 Jun.; 39(3): 378-389.

https://doi.org/10.1016/j.virs.2024.03.005‍

5. CK8+细胞在介导新冠肺炎患者肺泡损伤-重建中的关键作用

作者：

李玉凤，胡恒睿，刘佳，马龙达，汪习，刘良，刘茜，任亮，李江，邓菲，胡志红，周亦武，王曼丽

Crucial role played by CK8+ cells in mediating alveolar injury remodeling for patients with COVID-19

Virol Sin. 2024 Jun.; 39(3): 390-402.

https://doi.org/10.1016/j.‍virs.2024.03.007

6. 伪狂犬病病毒操纵线粒体色氨酰-tRNA合成酶2促进病毒复制

作者：

李秀青，蔡梦攀，王铭洋，史博文，杨国宇，王江，褚贝贝，明胜利

Pseudorabies virus manipulates mitochondrial tryptophanyl-tRNA synthetase 2 for viral replication

Virol Sin. 2024 Jun.; 39(3): 403-413.

https://doi.org/10.1016/j.virs.20‍24.04.003

7. COVID-19患者和SARS-CoV-2小鼠模型中病毒附属蛋白体液免疫反应特征分析

作者：

李玉明，唐艳红，王晓倩，朱爱如，刘冬冬，何艺芸，郭虎，郑杰，刘芯卓，迟凤瑜，王延群，庄珍，张昭勇，刘冬兰，陈钊，李芳，冉伟，余快，王东，文李艳，卓健芬，张艳君，席寅，肇静娴，赵金存，孙静

Characterization of humoral immune responses against SARS-CoV-2 accessory proteins in infected patients and mouse model

Virol Sin. 2024 Jun.; 39(3): 414-421.

‍https://doi.org/10.1016/j.virs.2024.04.005‍

8. 将HiBiT整合到肠道病毒中：推进肠道病毒学研究的通用工具

作者：

喻锐，李肖宏，张鹏，徐明昊，赵纪曈，闫静静，邱趁丽，束佳熠，张硕，康苗苗，张晓燕，徐建青，章树业

Integration of HiBiT into enteroviruses: A universal tool for advancing enterovirus virology research

Virol Sin. 2024 Jun.; 39(3): 422-433.

https://doi.org/10.1016/j.virs.2‍024.03.004

9. BSL-2下埃博拉病毒病替代模型的建立与应用

作者：

杨宛莹，李武建，周兀婕，王申，王玮琦，王振山，冯娜，王铁成，谢英，赵永坤，闫飞虎，夏咸柱

Establishment and application of a surrogate model for human Ebola virus disease in BSL-2 laboratory

Virol Sin. 2024 Jun.; 39(3): 434-446.

https://doi.org/10.1016/j.virs.2024.03‍.010

10. 一种可用于体内外抗病毒筛选的优化高通量SARS-CoV-2双报告基因反式互补系统

作者：

李颖健，谭雪，邓积凯，刘雪梅，刘乾运，张贞，黄晓雅，沈超，徐可，周立，陈宇

An optimized high-throughput SARS-CoV-2 dual reporter trans-complementation system for antiviral screening in vitro and in vivo

Virol Sin. 2024 Jun.; 39(3): 447-458.

https://doi.o‍rg/10.1016/j.virs.2024.03.009

11. 勐腊病毒迷你基因组的开发及其聚合酶复合物与其他丝状病毒的比较

作者：

谢诗哲，姚珂，李贝，彭诚，杨兴娄，石正丽

Development of a Měnglà virus minigenome and comparison of its polymerase complexes with those of other filoviruses

Virol Sin. 2024 Jun.; 39(3): 459-468.

https://doi.org/10.1016/j.virs.2024.0‍3.011

12. 非洲猪瘟病毒p11.5蛋白在病毒感染中的作用

作者：

尹丹，石彬，耿仁浩，刘英楠，龚浪，邵红霞，钱琨，陈鸿军，秦爱建

Function investigation of p11.5 in ASFV infection

Virol Sin. 2024 Jun.; 39(3): 469-477.

‍https://doi.org/10.1016/j.virs.2024.05.007‍

13. 基于抗p72和CD2v蛋白纳米抗体建立2种检测猪血清中抗非洲猪瘟病毒抗体的cELISAs

作者：

朱家宏，刘青源，李柳亚，张润宇，畅悦婷，赵加凯，刘思雨，赵芯钰，陈旭，孙亚妮，赵钦

Nanobodies against African swine fever virus p72 and CD2v proteins as reagents for developing two cELISAs to detect viral antibodies

Virol Sin. 2024 Jun.; 39(3): 478-489.

https://doi.org/10.1016/j.virs.202‍4.04.002

14. DNA疫苗初免-复制型痘苗病毒载体疫苗加强免疫小鼠诱导针对MERS-CoV的高水平体液和细胞免疫反应

作者：

申秀丽，王书晖，郝彦玲，付雨雨，任莉，李丹，唐雯琪，李静，陈冉，朱美玲，王硕，刘颖，邵一鸣

DNA vaccine prime and replicating vaccinia vaccine boost induce robust humoral and cellular immune responses against MERS-CoV in mice

Virol Sin. 2024 Jun.; 39(3): 490-500.

https://doi.org/10.1016/j.virs.2024.05.005‍

15. 钙调样蛋白5通过调节晚期内体合成和先天免疫反应促进PEDV复制

作者：

田文骏，张修忠，王警，刘剑锋，李复煌，王晓佳

Calmodulin-like 5 promotes PEDV replication by regulating late-endosome synthesis and innate immune response

Virol Sin. 2024 Jun.; 39(3): 501-512.

https://doi.org‍/10.1016/j.virs.2024.05.006

16. 由猫接触引起的发热伴血小板减少综合征病毒感染：中国北京一例病例报告

作者：

张烁，冷昱，张发雪，付伯康，吴炳征，陈家浩，崔宁，赵宁，刘玮，黎浩

Severe fever with thrombocytopenia syndrome virus infection attributed to cat contact: A case report in Beijing, China

Virol Sin. 2024 Jun.; 39(3): 513-515.

https://doi.org/10.1016/j.virs.2024.03.006

17. 一种可用于EBOV靶向预防性疫苗评价的重组水泡性口炎病毒小鼠致死模型

作者：

张宏庆，张哲瑞，邓成林，袁志明，张波

A lethal mice model of recombinant vesicular stomatitis viruses for EBOV-targeting prophylactic vaccines evaluation

Virol Sin. 2024 Jun.; 39(3): 516-519.

https://doi.org/10.1016/j.virs.2024.03.008‍

18. 2023年初中国H1N1流感病毒的遗传特征

作者：

李萱萱，董泽丰，李佳明，窦川然，田德雨，马正海，刘文军，高福，毕玉海

Genetic characteristics of H1N1 influenza virus outbreak in China in early 2023

Virol Sin. 2024 Jun.; 39(3): 520-523.

https://doi.org/10.1016/j.vi‍rs.2024.05.003

往期阅读：

期刊简介

《中国病毒学（英文）》Virologica Sinica, 是中国科学院武汉病毒研究所和中国微生物学会共同主办的病毒学领域的专业学术期刊。主要刊载病毒学及分支领域的前沿研究及最新进展。本刊最新影响因子（JCR2023）4.3, CiteScore 2023 9.3, 排位进入病毒学领域Q1区，并连续十一年入选“中国最具国际影响力学术期刊”（TOP 5%）。期刊于2022年变更为以金色开放获取模式出版的开源期刊（Open Access Journal），与科爱出版社合作全球出版传播。本刊为中国科技核心期刊，且被SCI、PubMed/Medline、PubMed Central、Scopus等数据库收录。

http://mp.weixin.qq.com/s?__biz=MzIyODIxMDg2Ng==&mid=2651857287&idx=1&sn=c564ab08dc15fb528992a577da4ef59b

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