药明康德有机合成路线设计与官能团转化擂台赛2024年第一期竞赛试题
学术
科技
2024-03-01 11:20
上海
各位化学同仁：
元夕已过，然新年的余温犹存。宝马雕车，凤箫声动，玉壶光转，依旧历历在目。细雨婆娑，料峭轻寒，2024年第一期有机合成路线设计与官能团转化擂台赛也追随着新春的脚步如约而至。
顾名思义，今年的竞赛形式略有改动，合成路线设计与官能团转化的考察将交替展开。本期着眼于前者，为大家带来六道合成路线设计题。且随我们屏气凝神，思忖二三，解题过程中或许会有新的收获。文末附有往期试题，供君一览。试题解析还将以网络直播的形式择时分享，敬请关注！
Please propose two reasonable synthetic routes to synthesize below target starting from commercially available reagents (20 points).2. 设计两条路线合成以下化合物，要求一条路线必须包含合成吡啶环，另一条路线必须包含合成高哌啶环（20分）。 Please propose two reasonable synthetic routes to synthesize below target starting from commercially available reagents, with which one route to synthesize the pyridine ring and the other to synthesize the azepine ring (20 points).Please propose two reasonable synthetic routes to synthesize below target starting from commercially available reagents (20 points).Please propose two reasonable synthetic routes to synthesize below target starting from commercially available reagents (20 points).Please propose two reasonable synthetic route to synthesize below target starting from commercially available reagents (20 points).Please propose one reasonable synthetic route to synthesize below chiral target starting from commercially available reagents (20 points).感谢回顾往期竞赛试题及解析，如有任何建议，欢迎留言交流讨论！
