CityReads | How We Die?

楼市   2024-11-15 21:50   上海  

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How We Die?


Heart disease, cancer, cerebrovascular diseases, respiratory diseases, and endocrine, nutritional, and metabolic disorders are the top five leading non-communicable disease causes among Chinese residents.

Max Roser (2021) - “Causes of death globally: what do people die from?” Published online at OurWorldinData.org. Retrieved from: 'https://ourworldindata.org/causes-of-death-treemap'[Online Resource]

Sources:https://ourworldindata.org/causes-of-death-treemap

https://ourworldindata.org/causes-of-death

Data analysis is one of my areas of interest, and understanding the world and China through data and facts is a commitment I have been pursuing. Over the past few years, I have been teaching the course Understanding China With Data, using publicly available data to analyze and understand the realities of Chinese society. I have decided to share the lecture materials I’ve written on CityReads.

A few months ago, I published an essay on CityReads analyzing China’s college entrance examination (Gaokao) with data, shedding light on the transformation of China’s higher education system (For more details, see CityReads | Higher Education Transitions in China) Today, I am using data to analyze the composition and changes in the causes of death among Chinese residents, providing insights into China’s health transition.

To move toward a healthier world and a healthier China, we must fully understand the health challenges we face today. Among these challenges, understanding how we die is a particularly meaningful question, as it helps identify effective ways to save lives and improve public health.

Epidemiologists classify causes of death into three major categories: non-communicable diseases, communicable diseases, and injuries. Injuries form a broad category that includes both accidents, such as car crashes and falls, and intentional harm, such as homicide, war-related deaths, and suicide. Globally, non-communicable diseases are the leading causes of death.

The chart below shows the number and distribution of deaths worldwide in 2019. Each rectangle in the chart represents a cause of death, with the size of the rectangle proportional to its share. In 2019, approximately 55 million people died worldwide. Of these, 74% died from non-communicable diseases, 14% from communicable diseases, and about 8% from injuries. (Note that the total does not add up to 100% due to other causes not included in the chart.)

Source:https://ourworldindata.org/causes-of-death-treemap

In the chart, the blue section represents non-communicable diseases, which are the most common causes of death. Cardiovascular diseases rank first, accounting for one-third of all deaths globally. Cancer comes second, responsible for 18% of deaths worldwide, followed by chronic respiratory diseases, which account for 7% of deaths. Digestive diseases, neurodegenerative diseases, and diabetes follow, contributing to 4.5%, 3.9%, and 2.9% of deaths, respectively.

The red section in the chart represents communicable diseases, which are caused by pathogens that can spread from person to person. In 2019, about one in seven deaths globally was due to communicable diseases, including pneumonia, diarrhea, tuberculosis, HIV/AIDS, and malaria.

The green section of the chart represents injuries. In 2019, traffic accidents accounted for 2.3% of all deaths, other accidents (such as falls, drowning, and fires) made up 3.1%, suicides accounted for 1.3%, and deaths from interpersonal violence, including homicide or war-related fatalities, were less than 1%.

The proportions of causes of death differ significantly from media coverage and public perception. Some major causes of death receive little attention, while causes heavily reported in the media often account for a relatively small proportion. For instance, globally, deaths from diarrhea account for 2.7%—much higher than the total share of deaths from all forms of violence (homicide, war, and terrorism), which is less than 1%.

How Chinese Residents Die?

According to data from the National Health Commission of China, the causes of death among Chinese residents are categorized into 19 specific subtypes, which can generally be grouped into three major categories: non-communicable diseases, communicable diseases, and injuries/poisoning due to external causes.

Non-communicable diseases include 14 types of illnesses: heart disease, malignant tumors (cancer), cerebrovascular diseases, respiratory diseases, endocrine, nutritional, and metabolic disorders, digestive system diseases, nervous system diseases, genitourinary system diseases, mental disorders, musculoskeletal and connective tissue diseases, blood, hematopoietic, and immune diseases, congenital malformations, deformations, and chromosomal abnormalities, perinatal diseases, and complications of pregnancy, childbirth, and the postpartum period.

Communicable diseases consist of infectious and parasitic diseases. Infectious diseases include dysentery, other bacterial intestinal infections, respiratory tuberculosis, tetanus, meningococcal infections, sepsis, sexually transmitted diseases, rabies, epidemic Japanese encephalitis, viral hepatitis, and HIV/AIDS. Parasitic diseases primarily include schistosomiasis.

Injuries and poisoning include traffic accidents, accidental poisoning, accidental falls, fires, drowning, mechanical asphyxiation, being crushed to death, electrocution, suicide, and homicide.

Other causes include undiagnosed and miscellaneous diseases, and it is worth noting that the sum of all 19 causes does not add up to 100%.

Similar to global trends, non-communicable diseases are the leading cause of death among Chinese residents, accounting for an overwhelming majority. As shown in the charts below, in 2021, non-communicable diseases accounted for 88.89% of deaths among rural residents and 90.34% among urban residents.

The proportion of deaths caused by communicable diseases in China is far lower than the global average (14%). In 2021, communicable diseases accounted for 0.89% and 0.83% of deaths among rural and urban residents, respectively. Injuries and poisoning accounted for 7.13% of deaths in rural areas and 5.46% in urban areas.

Source: calculated based on data from National Health Commission of China

Source: calculated based on data from National Health Commission of China

Now let’s look at the detailed composition of non-communicable disease (NCD) deaths among Chinese residents. In 2021, the leading causes of NCD deaths among rural residents in China, ranked from highest to lowest, were as follows:

1.Heart     disease, accounting for 25.36%

2.Cerebrovascular     diseases, accounting for 23.62%

3.Cancer,     accounting for 22.47%

4.Respiratory     diseases, accounting for 8.77%

5.Endocrine,     nutritional, and metabolic disorders, accounting for     2.84%

6.Digestive     system diseases, accounting for 2.15%

7.Nervous     system diseases, accounting for 1.37%

8.Genitourinary     system diseases, accounting for 1.06%

9.Mental     disorders, accounting for 0.48%

10.Musculoskeletal     and connective tissue diseases, accounting for     0.33%

11.Diseases     of the blood, hematopoietic organs, and immune system,     accounting for 0.18%

12.Congenital     malformations, deformations, and chromosomal abnormalities,     accounting for 0.14%

13.Perinatal     diseases, accounting for 0.11%

14.Complications     of pregnancy, childbirth, and the postpartum period,     accounting for 0.01%

Source:National Health Commission of China

Note: The chart only includes causes of death with a proportion exceeding 1%.

In 2021, the leading causes of non-communicable disease (NCD) deaths among urban residents in China, ranked from highest to lowest, were as follows:

1.Heart     disease, accounting for 25.64%

2.Cancer,     accounting for 24.61%

3.Cerebrovascular     diseases, accounting for 21.71%

4.Respiratory     diseases, accounting for 8.45%

5.Endocrine,     nutritional, and metabolic disorders, accounting for     3.74%

6.Digestive     system diseases, accounting for 2.39%

7.Nervous     system diseases, accounting for 1.46%

8.Genitourinary     system diseases, accounting for 1.05%

9.Mental     disorders, accounting for 0.54%

10.Musculoskeletal     and connective tissue diseases, accounting for     0.3%

11.Diseases     of the blood, hematopoietic organs, and immune system,     accounting for 0.21%

12.Congenital     malformations, deformations, and chromosomal abnormalities,     accounting for 0.13%

13.Perinatal     diseases, accounting for 0.11%.

Source:National Health Commission of China

Note: The chart only includes causes of death with a proportion exceeding 1%.

Comparing Differences in Non-Communicable Disease Death Causes Between Urban and Rural Residents in China (2021)

The proportion of urban residents dying from cancer is slightly higher than that of rural residents (24.61% vs. 22.47%). Conversely, the proportion of urban residents dying from cerebrovascular diseases is slightly lower than that of rural residents (21.71% vs. 23.62%). The proportion of deaths caused by endocrine, nutritional, and metabolic disorders is higher among urban residents than rural residents (3.74% vs. 2.84%). Urban residents have a lower proportion of deaths from complications of pregnancy, childbirth, and the postpartum period; while rural residents' proportion stands at 0.01%, this figure is so low among urban residents that it is statistically recorded as zero.

These differences in non-communicable disease mortality between urban and rural residents highlight disparities in healthcare access and lifestyle between the two populations.

Changes in the Composition of Causes of Death in China (1990 vs. 2021)

Comparing 1990 with 2021, non-communicable diseases (especially chronic and degenerative diseases) remain the leading causes of death among Chinese residents, and their proportion has increased over time. Among urban residents, the proportion rose from 86.29% in 1990 to 90.34% in 2021. For rural residents, the figure increased from 82.01% in 1990 to 88.89% in 2021.

In contrast, the proportion of deaths caused by communicable diseases has significantly declined. Among urban residents, it dropped from 3.57% in 1990 to 0.83% in 2021, while for rural residents, it fell from 5.66% to 0.89%. Similarly, the proportion of deaths caused by injuries and poisoning has also decreased. For urban residents, it declined from 6.91% in 1990 to 5.46% in 2021, and for rural residents, it fell from 10.65% to 7.13%.

Epidemiological Transition in China (1949–2023)

Since 1949, China has undergone demographic and epidemiological transitions, moving from a high birth rate and high mortality rate to a low birth rate and low mortality rate. Causes of death have shifted from predominantly infectious diseases to non-communicable diseases. Life expectancy has more than doubled, rising from 35 years before 1949 to 78.6 years in 2023. Chronic and degenerative diseases have become the dominant causes of death in this evolving health landscape.

Source:National Health Commission of China

Composition of Non-Communicable Disease Mortality Causes

In 1990, the top five causes of death from non-communicable diseases among urban residents in China were cancer, cerebrovascular diseases, heart disease, respiratory diseases, and digestive system diseases. Among rural residents, the top five causes were respiratory diseases, cancer, cerebrovascular diseases, heart disease, and digestive system diseases.

By 2021, the top five non-communicable disease causes of death among urban residents had shifted to heart disease, cancer, cerebrovascular diseases, respiratory diseases, and endocrine, nutritional, and metabolic disorders. Among rural residents, the top five non-communicable disease causes were heart disease, cerebrovascular diseases, cancer, respiratory diseases, and endocrine, nutritional, and metabolic disorders.

With rapid urbanization, heart disease, cancer, and cerebrovascular diseases have become the leading non-communicable disease causes of death for both urban and rural residents in China.

Source:National Health Commission of China

In his book Outlive: The Science and Art of Longevity, Dr. Peter Attia explains how the world has transitioned from a "fast death" to a "slow death" society since 1900. In 1900, the global average life expectancy was less than 50 years, and most people died from "fast" causes such as accidents, injuries, and various infectious diseases. By 2021, the global average life expectancy had risen to 71 years, with chronic diseases of aging becoming the primary causes of death.

Dr. Attia categorizes these chronic diseases into what he calls the "Four Horsemen of Death": cardiovascular disease (CVD), cancer, neurodegenerative diseases, and diabetes along with related metabolic disorders (for more details, see CityReads | Outlive: How to Extend Healthspan?).

Today, the primary non-communicable disease causes of death among Chinese residents align closely with the "Four Horsemen." Achieving healthy longevity requires understanding and addressing the root causes of these chronic diseases as early as possible.

CityQuotes

1.“P53 may also hold the key to Peto’s paradox, an oddity observed in the 1970s by the British epidemiologist Richard Peto. Large animals such as elephants or whales can have a hundred times as many cells as we do. Even accounting for their slower metabolism, this means there is a much greater chance that one of their cells will mutate to become cancerous. Yet these large mammals are remarkably resistant to cancer and live almost as long or even longer than us. Humans inherit one copy of the gene for p53 from each of our parents, but it turns out that elephants have twenty copies. Therefore their cells are exquisitely sensitive to DNA damage and commit suicide when it is detected.” - Venki Ramakrishnan, Why We Die: The New Science of Aging and the Quest for Immortality

2.“Toward the end of World War II, between September 1944 and May 1945, the Netherlands suffered from a devastating famine that would claim the lives of more than 20,000 people. A later study showed that despite the relatively brief duration of the famine, the children of women who were pregnant during the mass starvation suffered adverse physical and mental health consequences throughout their lives. They experienced higher rates of obesity, diabetes, and schizophrenia, and had a higher mortality than children who were not in utero during the famine. The effects were even different depending on whether the famine occurred in the early or late stages of pregnancy. Comparing the DNA of subjects who had experienced starvation in utero with those of their older and younger siblings was revealing: the famine had imposed on the fetus a methylation pattern that had consequences over the course of its life and accelerated both aging-related diseases and mortality. It is a striking example of how an external stress can cause epigenetic changes to DNA that last a lifetime.”- Venki Ramakrishnan, Why We Die: The New Science of Aging and the Quest for Immortality


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