翻译：张恒睿 徐州医科大学2024级硕士研究生
审校：赵林林 徐医附院麻醉科
《Anaesthesia Critical Care & Pain Medicine》2024年10月刊，第43卷第5期
《Anaesthesia Critical Care & Pain Medicine》2024年8月刊，第43卷第4期
《Anaesthesia Critical Care & Pain Medicine》2024年6月刊，第43卷第3期
《Anaesthesia Critical Care & Pain Medicine》2024年4月刊，第43卷第2期
《Anaesthesia Critical Care & Pain Medicine》2024年2月刊
Editorials
社论
1.Incidence and clinical impact of aspiration during cesarean delivery: A multi-center retrospective study: Addressing the hidden risk: Aspiration during cesarean delivery
剖宫产误吸的发生率和临床影响： 多中心回顾性研究： 应对隐藏的风险： 剖宫产误吸
2.Incidence of unplanned extubation in French intensive care units: are we ready for a SAFE-ICU plan!
法国重症监护病房意外拔管的发生率：我们是否准备好实施 SAFE-ICU 计划！
Original articles
原创文章
1.Effects of dexmedetomidine versus propofol on outcomes in critically ill patients with different sedation depths: a propensity score-weighted cohort study
右美托咪定与异丙酚对不同镇静深度重症患者预后的影响：倾向得分加权队列研究
Abstract
摘要
Objective
研究目的
We explored the effects of dexmedetomidine (DEX) versus propofol on outcomes in critically ill patients and to assess whether these effects are dissimilar under different sedation depths.
我们探讨了右美托咪定（DEX）与异丙酚对重症患者预后的影响，并评估了这些影响在不同镇静深度下是否不同。
Methods
方法
A stabilized inverse probability of treatment weighting cohort study was conducted using data from the Medical Information Mart for Intensive Care IV database from 2008 to 2019. Adult intensive care unit (ICU) patients who were administered DEX or propofol as the primary sedative were identified. Various statistical methods were used to evaluate the effects of DEX versus propofol on outcomes.
利用 2008 年至 2019 年重症监护医学信息市场 IV 数据库中的数据，开展了一项稳定的逆概率治疗加权队列研究。研究确定了使用 DEX 或丙泊酚作为主要镇静剂的成人重症监护病房（ICU）患者。研究采用多种统计方法评估了DEX与异丙酚对疗效的影响。
Results
结果
Data on 107 and 2318 patients in DEX and propofol groups, respectively, were analyzed. Compared to the propofol group, the DEX group exhibited longer ventilator-free days on day 28 and a shorter ICU stay. Conversely, it showed null associations of DEX with the risk of 90-day ICU mortality, the odds of persistent organ dysfunction on day 14 and acute kidney injury, and the duration of vasopressor-free days on day 28. Subgroup analyses revealed that DEX positively impacted persistent organ dysfunction on day 14, ventilator-free days on day 28, and ICU stay in the subgroup with a Richmond Agitation Sedation Scale (RASS) score of ≥−2. However, DEX negatively impacted 90-day ICU mortality, persistent organ dysfunction on day 14, and ventilator-free days on day 28 in the subgroup with a RASS score of <−2.
对DEX组和丙泊酚组分别107名和2318名患者的数据进行了分析。与异丙酚组相比，DEX 组第 28 天无呼吸机天数更长，重症监护室住院时间更短。相反，DEX与重症监护室90天死亡风险、第14天持续器官功能障碍和急性肾损伤的几率以及第28天无呼吸机天数的持续时间呈负相关。亚组分析显示，在里士满躁动镇静量表（RASS）评分≥-2的亚组中，DEX对第14天持续器官功能障碍、第28天无呼吸机天数和ICU住院时间有积极影响。然而，DEX对RASS评分<-2的亚组的90天ICU死亡率、第14天持续器官功能障碍和第28天无呼吸机天数有负面影响。
Conclusion
结论
Our results indicated that, compared with propofol, DEX had beneficial and adverse impacts on certain ICU outcomes in critically ill patients, and these impacts appeared to depend on sedation depths.
我们的研究结果表明，与异丙酚相比，DEX 对重症患者在重症监护室的某些预后既有有利影响，也有不利影响，而这些影响似乎取决于镇静深度。
2.Integrating StEP-COMPAC definition and enhanced recovery after surgery status in a machine-learning-based model for postoperative pulmonary complications in laparoscopic hepatectomy
在基于机器学习的腹腔镜肝切除术术后肺部并发症模型中整合 StEP-COMPAC 定义和术后增强恢复状态
3.Effect of ventilation mode on postoperative pulmonary complications among intermediate- to high-risk patients undergoing abdominal surgery: A randomized controlled trial
通气模式对腹部手术中高危患者术后肺部并发症的影响： 随机对照试验
Abstract
摘要
Background
背景
The effect of different mechanical ventilation modes on pulmonary outcome after abdominal surgery remains unclear. We evaluated the effects of three common ventilation modes on postoperative pulmonary complications (PPCs) among intermediate- to high-risk patients undergoing abdominal surgery.
不同的机械通气模式对腹部手术后肺部预后的影响仍不明确。我们评估了三种常见通气模式对腹部手术中高危患者术后肺部并发症（PPCs）的影响。
Methods
方法
This randomized clinical trial enrolled adult patients at intermediate or high risk of PPCs who were scheduled for abdominal surgery. Participants were randomized to receive one of three modes of mechanical ventilation modes: volume-controlled ventilation (VCV), pressure-controlled ventilation (PCV), and pressure-control with volume-guaranteed ventilation (PCV-VG). Lung-protective ventilation strategy was implemented in all groups. The primary outcome was the incidence of a composite of pulmonary complications within the first 7 postoperative days. Pulmonary complications within 30 postoperative days, the severity grade of PPCs, and other secondary outcomes were also analyzed.
这项随机临床试验招募了计划接受腹部手术的中高危成人患者。参与者被随机分配接受三种机械通气模式中的一种：容量控制通气（VCV）、压力控制通气（PCV）和带容量保证的压力控制通气（PCV-VG）。所有组别均采用肺保护通气策略。主要结果是术后 7 天内肺部并发症的综合发生率。此外，还分析了术后 30 天内的肺部并发症、PPCs 的严重程度等级以及其他次要结果。
Results
结果
A total of 1365 patients were randomized and 1349 were analyzed. The primary outcome occurred in 98 (21.8%) in the VCV group, 95 (22.1%) in the PCV group, and 101 (22.5%) in the PCV-VG group (P = 0.865). Additionally, there were no statistically significant differences among the three groups in terms of the incidence of pulmonary complications within postoperative 30 days, severity grade of PPCs, and other secondary outcomes.
共有 1365 名患者接受了随机治疗，其中 1349 人接受了分析。VCV 组中有 98 人（21.8%）、PCV 组中有 95 人（22.1%）、PCV-VG 组中有 101 人（22.5%）出现了主要结果（P = 0.865）。此外，在术后 30 天内肺部并发症的发生率、PPCs 的严重程度等级以及其他次要结果方面，三组之间没有显著的统计学差异。
Conclusion
结论
In intermediate- to high-risk patients undergoing abdominal surgery, the choice of ventilation mode did not affect the risk of PPCs.
在接受腹部手术的中高危患者中，通气模式的选择不会影响 PPC 的风险。
4.Accuracy of preoperative lung ultrasound score for the prediction of major adverse cardiac events in elderly patients undergoing HIP surgery under spinal anesthesia: The LUSHIP multicenter observational prospective study
椎管内麻醉下接受 HIP 手术的老年患者术前肺部超声评分预测重大心脏不良事件的准确性：LUSHIP 多中心前瞻性观察研究
5.Rapid uptake of adjunctive corticosteroids for critically ill adults with septic shock following publication of ADRENAL trial. A multicenter, retrospective analysis of prescribing practices in Queensland Intensive Care Units
ADRENAL 试验公布后，成人脓毒性休克重症患者迅速使用皮质类固醇辅助治疗。对昆士兰重症监护病房处方做法的多中心回顾性分析
6.Development and validation of a sepsis risk index supporting early identification of ICU-acquired sepsis: an observational study
脓毒症风险指数的开发与验证：一项观察性研究，支持早期识别重症监护室获得性脓毒症
7.Effect of perioperative erythropoietin on postoperative morbidity and mortality after cardiac surgery: a meta-analysis of randomized controlled trials
围手术期促红细胞生成素对心脏手术术后发病率和死亡率的影响：随机对照试验的荟萃分析
8.Opioid free versus opioid sparing strategies for multimodal antinociception during laparoscopic colectomy: a randomised controlled trial
腹腔镜结肠切除术中多模式止痛的无阿片策略与阿片疏导策略：随机对照试验
9.Efficacy of ultrasound guided sphenopalatine ganglion block in management of emergence agitation after sinoscopic nasal surgery: a randomized double-blind controlled study
超声引导下的蝶腭神经节阻滞治疗鼻窦镜手术后出现躁动的疗效：随机双盲对照研究
10.Is quantitative neuromuscular monitoring mandatory after administration of the recommended dose of sugammadex? A prospective observational study
使用推荐剂量的舒更葡糖后是否必须进行定量神经肌肉监测？前瞻性观察研究
11.Early deep-to-light sedation versus continuous light sedation for ICU patients with mechanical ventilation: A cohort study
对使用机械通气的重症监护病房患者进行早期深到浅镇静与持续浅镇静的比较： 一项队列研究
Guidelines
指导方针
1.Postoperative Pain Management in children: guidance from the Pain Committee of the European Society for Paediatric Anaesthesiology (ESPA Pain Management Ladder Initiative) Part II
儿童术后疼痛管理：欧洲儿科麻醉学会疼痛委员会指南（ESPA 疼痛管理阶梯倡议）第二部分
Review
回顾
1.Prophylactic application of dexmedetomidine reduces the incidence of emergence delirium in children: A systematic review and meta-analysis
预防性应用右美托咪定可降低儿童出现谵妄的几率： 系统回顾和荟萃分析
2.Is artificial intelligence prepared for the 24-h shifts in the ICU?
人工智能为重症监护室的 24 小时轮班做好准备了吗？
3.Hypocalcemia in critical care settings, from its clinical relevance to its treatment: A narrative review
重症监护环境中的低钙血症，从临床意义到治疗方法： 叙述性综述
4.Intraoperative ketamine and pain after video-assisted thoracoscopic surgery (VATS): A systematic review and meta-analysis
术中氯胺酮与视频辅助胸腔镜手术（VATS）后的疼痛： 系统回顾与荟萃分析
Short communications
短讯
1.Developing a sustainable team in critical care: focus on gender-based diversity
发展可持续的重症监护团队：关注性别多样性
Letters to the editor
致编辑的信
1.Motivations and barriers to clinical research participation among anaesthesiology and intensive care staff in France
法国麻醉学和重症监护人员参与临床研究的动机和障碍
