《Journal of Clinical Anesthesia》2024年11月刊,第98卷

文摘   2024-11-04 06:40   江苏  

翻译:史晨阳 徐医麻醉2024级硕士研究生

审校:赵林林 徐医附院麻醉科

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《Journal of Clinical Anesthesia》2024年11月刊,第98卷

Original Contributions

1.Effectiveness of a delirium risk assessment and multidisciplinary care approach in reducing delirium incidence among surgical intensive care unit patients: A retrospective pre-post intervention study

谵妄风险评估和多学科治疗方法对降低外科重症监护室患者谵妄发生率的有效性: 干预前-后回顾性研究

2.The effects of laryngeal mask versus endotracheal tube on atelectasis after general anesthesia induction assessed by lung ultrasound: A randomized controlled trial

肺部超声评估的喉罩与气管插管对全身麻醉诱导后肺不张的影响的比较:随机对照试验

3.Postoperative delirium risk in patients with hyperlipidemia: A prospective cohort study

高脂血症患者术后谵妄的风险:前瞻性队列研究

4.Recruitment-to-inflation ratio to assess response to PEEP during laparoscopic surgery: A physiologic study

腹腔镜手术期间通过肺复张-膨胀比评估对 PEEP 的反应:生理学研究

5.Impact of preoperative QTc interval prolongation on short-term postoperative outcomes: A retrospective study

术前QTc间期延长对术后短期预后的影响:回顾性研究

6.Desflurane versus sevoflurane anesthesia and postoperative recovery in older adults undergoing minor- to moderate-risk noncardiac surgery–A prospective, randomized, observer-blinded, clinical trial

地氟烷与七氟烷对接受轻度至中度风险非心脏手术的老年人的麻醉及术后恢复的影响的对比--一项前瞻性、随机、观察者盲法临床试验

7.Effect of remimazolam versus propofol on hypotension after anesthetic induction in patients undergoing coronary artery bypass grafting: A randomized controlled trial

瑞马唑仑与异丙酚对冠状动脉旁路移植术患者麻醉诱导后低血压的影响的比较:随机对照试验

8.Impact of nitrous oxide use on parturient recall of neuraxial analgesia risks

使用N₂O对产妇回忆椎管内镇痛风险的影响

9.Comprehensive perioperative blood management in patients undergoing elective bypass cardiac surgery: Benefit effect of health care education and systematic correction of iron deficiency and anemia on red blood cell transfusion

择期体外循环手术患者围术期血液综合管理: 保健教育和系统纠正缺铁和贫血对红细胞输注的益处

Abstract

Study objective

The aim of this study was to investigate the efficacy of a two-step patient blood management (PBM) program in red blood cell (RBC) transfusion requirements among patients undergoing elective cardiopulmonary bypass (CPB) surgery.

研究目的 本研究旨在探讨两步式患者血液管理(PBM)计划对接受择期体外循环(CPB)手术的患者输注红细胞(RBC)需求的影响。

Design

Prospective, non-randomized, two-step protocol design.

设计 

采用前瞻性、非随机、两步方案设计。

Setting

Cardiac surgery department of Clinique Pasteur, Toulouse, France.

地点 

法国图卢兹巴斯德诊所心脏外科。

Patients

897 patients undergoing for elective CPB surgery.

患者 

897 名接受择期 CPB 手术的患者。

Interventions

We conducted a two-steps protocol: PBMe and PBMc. PBMe involved a short quality improvement program for health care workers, while PBMc introduced a systematic approach to pre- and postoperative correction of deficiencies, incorporating iron injections, oral vitamins, and erythropoiesis-stimulating agents.

干预

我们采取了两步方案: PBMe 和 PBMc。 PBMe 为医护人员提供了一个短期的质量改进计划,而 PBMc 则引入了一种系统的方法以在术前和术后纠正微量元素缺乏症,包括注射铁剂、口服维生素和促红细胞生成素。

Measurements

The PBM program's effectiveness was evaluated through comparison with a pre-PBM retrospective cohort after propensity score matching. The primary objective was the proportion of patients requiring RBC transfusions during their hospital stay. Secondary objectives were also analyzed.

测量方法 

经过倾向得分匹配后,通过与实施 PBM 前的回顾性队列进行比较,评估 PBM 计划的有效性。 主要目标是住院期间需要输注红细胞的患者比例。 此外,还对次要目标进行了分析。

Main results

After matching, 343 patients were included in each group. Primary outcomes were observed in 35.7% (pre-PBM), 26.7% (PBMe), and 21.1% (PBMc) of patients, resulting in a significant reduction (40.6%) in the overall RBC transfusion rate. Both the PBMe and PBMc groups exhibited significantly lower risks of RBC transfusion compared to the pre-PBM group, with adjusted odds ratios of 0.59 [95% CI 0.44–0.79] and 0.44 [95% CI 0.32–0.60], respectively. Secondary endpoints included reductions in transfusions exceeding 2 units, total RBC units transfused, administration of allogeneic blood products, and total bleeding volume recorded on Day 1. There were no significant differences noted in mortality rates or the duration of hospital stays.

主要结果 

经过配对,每组共纳入 343 名患者。 35.7%(pre-PBM)、26.7%(PBMe)和 21.1%(PBMc)的患者观察到了主要结果,从而使整体 RBC 输血率显著降低(40.6%)。 与 pre-PBM组相比,PBMe 组和 PBMc 组的 RBC 输血风险都明显降低,调整后的几率比分别为 0.59 [95% CI 0.44-0.79] 和 0.44 [95% CI 0.32-0.60]。 次要终点包括输血量减少超过 2 个单位、输注的红细胞总数、异体血制品用量和第 1 天记录的总出血量。 死亡率和住院时间没有明显差异。

Conclusions

This study suggests that health care education and systematic deficiency correction are associated with reduced RBC transfusion rates in elective CPB surgery. However, further randomized, controlled studies are needed to validate these findings and refine their clinical application.

结论 

本研究表明,在择期 CPB 手术中,医疗保健教育和系统性纠正微量元素缺乏与降低红细胞输注率有关。不过,还需要进一步的随机对照研究来验证这些发现并完善其临床应用。

10.The evaluation of the performance of ChatGPT in the management of labor analgesia

评估 ChatGPT 在分娩镇痛管理中的作用

11.Effects of neuromuscular block reversal with neostigmine/glycopyrrolate versus sugammadex on bowel motility recovery after laparoscopic colorectal surgery: A randomized controlled trial

使用新斯的明/格隆溴铵与使用舒更葡糖进行神经肌肉阻滞逆转对腹腔镜结直肠手术后肠蠕动恢复的影响的比较:随机对照试验

12.A new video laryngoscope combined with flexible laryngeal mask insertion: A prospective randomized study

新型视频喉镜与可弯曲喉罩插入的结合: 前瞻性随机研究

13.Intraoperative methadone administration for total mastectomy: A single center retrospective study

全乳房切除术术中美沙酮给药: 单中心回顾性研究

Abstract

Background

Breast cancer is the most frequent type of cancer and the second leading cause of cancer-related mortality in women. Mastectomies remain a key component of the treatment of non-metastatic breast cancer, and strategies to treat acute postoperative pain, a complication affecting nearly all patients undergoing surgery, continues to be an important clinical challenge. This study aimed to determine the impact of intraoperative methadone administration compared to conventional short-acting opioids on pain-related perioperative outcomes in women undergoing a mastectomy.

背景 

乳腺癌是最常见的癌症类型,也是女性癌症相关死亡的第二大原因。 乳房切除术仍是非转移性乳腺癌治疗的关键组成部分,而术后急性疼痛是几乎所有接受手术的患者都会出现的并发症,其治疗策略仍是一项重要的临床挑战。 本研究旨在确定与传统短效阿片类药物相比,术中使用美沙酮对接受乳房切除术的妇女疼痛相关围手术期结果的影响。

Methods

This single-center retrospective study included adult women undergoing total mastectomy. The primary outcome of this study was postoperative pain intensity on day 1 after surgery. Secondary outcomes included perioperative opioid consumption, perioperative non-opioid analgesics use, duration of surgery and anesthesia, time to extubation, pain intensity in the postanesthesia care unit (PACU), anti-emetic use in PACU, and length of stay in hospital. We used the propensity score-based nearest matching with a 1:3 ratio to balance the patient baseline characteristics.

方法 

这项单中心回顾性研究包括接受全乳房切除术的成年女性。 研究的主要结果是术后第 1 天的疼痛强度。 次要结果包括围手术期阿片类药物用量、围手术期非阿片类镇痛药用量、手术和麻醉持续时间、拔管时间、麻醉恢复室(PACU)的疼痛强度、PACU的止吐药用量和住院时间。 我们采用基于倾向评分的最近匹配法,以 1:3 的比例平衡患者的基线特征。

Results

133 patients received methadone, and 2192 patients were treated with short-acting opioids. The analysis demonstrated that methadone was associated with significantly lower intraoperative and postoperative opioid consumption as measured by oral morphine equivalents and lower average pain intensity scores in the postanesthesia care unit. Moreover, methadone was also shown to reduce the use of non-opioid analgesia during surgery.

结果 

133 名患者接受了美沙酮治疗,2192 名患者接受了短效阿片类药物治疗。 分析表明,以口服吗啡当量衡量,美沙酮可显著降低术中和术后阿片类药物的消耗量,并降低PACU的平均疼痛强度评分。 此外,美沙酮还能减少手术期间非阿片类镇痛药的使用。

Conclusion

Our study suggests that the unique pharmacological properties of methadone, including a short onset of action when given intravenously, long-acting pharmacokinetics, and multimodal effects, are associated with better acute pain management after a total mastectomy.

结论 

我们的研究表明,美沙酮的独特药理特性(包括静脉注射起效时间短、长效药代动力学和多模式效应)与更好地控制乳房全切术后的急性疼痛有关。

14.Huaxi integrated blood management reduces the red blood cell transfusion for on-pump cardiac surgery: A quasi-experimental study

华西综合血液管理减少了体外循环心脏手术的红细胞输注: 准实验研究

15.The association between intraoperative low driving pressure ventilation and perioperative healthcare-associated costs: A retrospective multicenter cohort study

术中低驱动压力通气与围手术期相关医疗费用之间的关系: 一项回顾性多中心队列研究

16.A technology acceptance model to predict anesthesiologists' clinical adoption of virtual reality

预测麻醉医生临床采用虚拟现实技术的技术接受模型

17.Since the COVID-19 pandemic, approximately 90% of elective anesthetics have been ambulatory: A retrospective analysis of statewide data in Florida from 2010 through 2022

自 COVID-19 大流行以来,约90%的择期麻醉都是门诊麻醉:对 2010 年至 2022 年佛罗里达州全州数据的回顾性分析

Correspondence

1.Reply to editorial: Videolaryngoscopy is superior to direct laryngoscopy: It's time to change our clinical practice!

回复社论:视频喉镜检查优于直接喉镜检查:是时候改变我们的临床实践了!

2.From bench to bed: Safe brain initiative care bundle strategies for postoperative delirium

从科研到临床:针对术后谵妄的安全大脑倡议(SBI)集束化治疗策略

3.Letter to the editor regarding “Low intraoperative end-tidal carbon dioxide levels are associated with improved recurrence-free survival after elective colorectal cancer surgery”

致编辑的信,内容涉及 "术中低潮气末二氧化碳水平与提高择期结直肠癌手术后无复发生存率有关"

4.Response to comment on: “Comparison of volume-controlled ventilation, pressure-controlled ventilation and pressure-controlled ventilation-volume guaranteed in infants and young children in the prone position: A prospective randomized study”

对以下评论的答复 对 "俯卧位婴幼儿容量控制通气、压力控制通气和通气压力控制通气-容量保证的比较: 前瞻性随机研究"

5.Comment on: Comparison of volume-controlled ventilation, pressure-controlled ventilation and pressure-controlled ventilation-volume guaranteed in infants and young children in the prone position: A prospective randomized study

评论 俯卧位婴幼儿容量控制通气、压力控制通气和通气压力控制通气-容量保证的比较: 前瞻性随机研究

6.Letter to the editor regarding “Postoperative delirium risk in patients with hyperlipidemia: A prospective cohort study”

致编辑的信,关于 "高脂血症患者术后谵妄的风险: 前瞻性队列研究"

7.Reply letter: Videolaryngoscopy is superior to direct laryngoscopy

回信: 视频喉镜检查优于直接喉镜检查

8.Letter to the editor, “Evaluating the accuracy of ChatGPT-4 in predicting ASA scores: A prospective multicentric study ChatGPT-4 in ASA score prediction”

致编辑的信,"评估 ChatGPT-4 预测 ASA 评分的准确性: 一项前瞻性多中心研究 ChatGPT-4 在 ASA 评分预测中的应用"。

9.In response to ‘Educating the next generation: unprofessionalism in anesthesiology residency programs’

回应 "教育下一代:麻醉住院医师培训项目中的不专业现象

Review

1.Analgesic efficacy and safety of erector spinae plane block in pediatric patients undergoing elective surgery: A systematic review and Meta-analysis of randomized controlled trials

对接受择期手术的儿科患者进行竖脊肌平面阻滞的镇痛效果和安全性: 随机对照试验的系统综述和荟萃分析

2.Early exposure to general anesthesia may contribute to later attention-deficit/hyperactivity disorder (ADHD): A systematic review and meta-analysis of cohort studies

早期接触全身麻醉可能会导致日后出现注意力缺陷/多动症(ADHD): 队列研究的系统综述和荟萃分析

3.Comparing oxygen therapies for hypoxemia prevention during gastrointestinal endoscopy under procedural sedation: A systematic review and network meta-analysis

在程序镇静下进行消化内镜检查时预防低氧血症的氧疗的比较: 系统回顾和网络荟萃分析


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介绍麻醉学专业知识,面向麻醉医生、麻醉学本科生和住培生。
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