2024年10月29日，由美敦力发起的“美力前行 导向未来——Pipeline™学术周”正式收官。来自美国佛罗里达州杰克逊维尔浸礼会健康系统神经学院的Ricardo A. Hanel教授到访国内三地，与国内神经介入专家就动脉瘤诊疗开展面对面学术交流，从循证证据到临床实践，探索血流导向密网支架的发展趋势和临床应用，并从典型病例出发探讨优化安全性和操作技术等的可行方案。
Ricardo A. Hanel教授在本次Pipeline™学术之旅中分享了他对于Pipeline™循证研究的理解，也分享了关于器械发展、临床应用效果及血流导向疗法未来趋势的观点，并强调了高质量循证数据支撑对于治疗的重要性。
热点话题
活动总结
血流导向疗法的出现改变了传统动脉瘤治疗的理念和模式，对于动脉瘤——尤其是复杂动脉瘤——的介入治疗是里程碑式的变革，带来了更安全、有效的治疗结果。本次学术周，中外专家共话血流导向疗法的最新研究、应用经验及未来发展，以期进一步助力血流导向疗法的临床诊疗，造福更多中国患者。
Pipeline™ Flex血流导向密网支架（简称Pipeline™ Flex）
Pipeline™ Flex with Shield Technology™（简称Pipeline™ Shield）
专家简介
Prof. Ricardo A. Hanel
MD, PhD
Director, Baptist Neurological Institute
Endowed Chair of Stroke and Cerebrovascular Surgery
Baptist Health System
Jacksonville, FL
Membership in Professional Organizations
SVIN
SNIS
WFITN
American Association of Neurological Surgeons International Member
CV SECTION AANS CNS
Congress of Neurological Surgeons International Member
World Federation of Neurological Societies Member
Brazilian Society of Neurosurgery (SBN) Member
Becske T, Brinjikji W, Potts MB, et al. Long-Term Clinical and Angiographic Outcomes Following Pipeline Embolization Device Treatment of Complex Internal Carotid Artery Aneurysms: Five-Year Results of the Pipeline for Uncoilable or Failed Aneurysms Trial. Neurosurgery. 2017;80(1):40-48. doi:10.1093/neuros/nyw014
Hanel RA, Kallmes DF, Lopes DK, et al. Prospective study on embolization of intracranial aneurysms with the pipeline device: the PREMIER study 1 year results. J Neurointerv Surg. 2020;12(1):62-66. doi:10.1136/neurintsurg-2019-015091
Rodriguez-Erazú F, Cortez GM, Lopes DK, et al. Braids and beyond: a comprehensive study on pipeline device braid stability from PREMIER data. J Neurointerv Surg. Published online October 1, 2024. doi:10.1136/jnis-2024-022350
Martínez-Galdámez M, Lamin SM, Lagios KG, et al. Treatment of intracranial aneurysms using the pipeline flex embolization device with shield technology: angiographic and safety outcomes at 1-year follow-up. J Neurointerv Surg. 2019;11(4):396-399. doi:10.1136/neurintsurg-2018-014204
Rice H, Martínez Galdámez M, Holtmannspötter M, et al. Periprocedural to 1-year safety and efficacy outcomes with the Pipeline Embolization Device with Shield technology for intracranial aneurysms: a prospective, post-market, multi-center study. J Neurointerv Surg. 2020;12(11):1107-1112. doi:10.1136/neurintsurg-2020-015943
Girdhar G, Li J, Kostousov L, Wainwright J, Chandler WL. In-vitro thrombogenicity assessment of flow diversion and aneurysm bridging devices. J Thromb Thrombolysis. 2015;40(4):437-443. doi:10.1007/s11239-015-1228-0
Girdhar G, Andersen A, Pangerl E, et al. Thrombogenicity assessment of Pipeline Flex, Pipeline Shield, and FRED flow diverters in an in vitro human blood physiological flow loop model. J Biomed Mater Res A. 2018;106(12):3195-3202. doi:10.1002/jbm.a.36514
Lylyk I, Scrivano E, Lundquist J, et al. Angiographic and clinical outcomes from 396 aneurysms treated with the pipeline flex embolization device with shield technology. Interv Neuroradiol. Published online April 30, 2024. doi:10.1177/15910199241231018
Matsuda Y, Jang DK, Chung J, Wainwright JM, Lopes D. Preliminary outcomes of single antiplatelet therapy for surface-modified flow diverters in an animal model: analysis of neointimal development and thrombus formation using OCT. J Neurointerv Surg. 2019;11(1):74-79. doi:10.1136/neurintsurg-2018-013935
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