TCT 2024|TCT全球最佳研究榜单:36项经导管心血管临床研究入选,届时呈现!

学术   2024-10-12 18:06   江苏  

10月27日至10月30日第36届年度经导管心血管治疗年会(TCT2024)会议将在美国华盛顿隆重开幕。TCT大会聚焦心血管介入领域最新研究和前沿科技,旨在通过介入治疗改善心脏病和血管疾病患者生存率和生活质量。

本年度TCT会议主题为“从干预到预防:实现持久结果的综合管理”,探索如何将预防措施与介入治疗相结合,以更全面地对抗和减轻心血管疾病。

在为期4天的会议期间设置了6场LBCT/LBCS,共26项冠脉疾病、结构性心脏病等心血管最新临床研究,届时呈现这些成果的顶尖科学家和来自全球的顶尖临床医生进行互动讨论,碰撞学术火花。

严道医声特此汇总整理,以供速览!

1

冠脉疾病系列之全球最佳研究


TCT WorldLink Forum: Best Global Research in Coronary Imaging

北京时间:11:30-12:30

1. Changes in Plaque Volume and Plaque Composition After 12 Weeks of Extensive LDL-C Reduction With PCSK9 Inhibitors in ACS Patients With Multivessel Disease: A Pre-Specified Lesion-Based Analysis of the Investigator-Initiated, Multicenter Randomized Placebo-Controlled FITTER Trial

ACS合并多血管病患者使用PCSK9抑制剂降低LDL-C 12周后斑块体积和斑块组成的变化:一项由研究者发起的多中心、随机、安慰剂对照FITTER试验的预先指定病变分析

2. Lipid Burden and Efficacy of Preventive PCI in Vulnerable Atherosclerotic Coronary Plaques: Post-hoc Analysis of PREVENT Trial

预防性PCI治疗易损动脉粥样硬化性冠状动脉斑块的脂质负担和疗效:PREVENT试验事后分析

3. OCT-Guided vs. Angiography-Guided Coronary Stent Implantation in Calcified Lesions: An ILUMIEN IV Substudy

OCT引导vs血管造影引导的钙化病变冠脉支架植入术:ILUMIEN IV子研究

4. Completeness of Revascularization by FFRCT and Long-term Prognosis in Stable Angina: A 7-Year Follow-up of the ADVANCE-DK Registry

FFR CT血运重建的完全性和稳定型心绞痛的长期预后:ADVANCE-DK Registry的7年随访

5. Integration of CT Angiography Into PCI Procedures

将CT血管造影整合到PCI手术中



TCT WorldLink Forum: Best Global Research in Physiology and Microcirculation

北京时间:16:00-17:15

1. ORBITA2-PHYSIOLOGY: Fractional Flow Reserve and Instantaneous Wave-Free Ratio as Predictors of the Placebo-Controlled Response to Percutaneous Coronary Intervention in Stable Coronary Artery Disease

ORBITA2-PHYSIOLOGY:血流储备分数(FFR)和瞬时无波比值(IFR)作为经皮冠状动脉介入治疗稳定型冠状动脉疾病中安慰剂对照反应的预测因子

2. Impact of Pullback Pressure Gradient on Patient-Reported Outcomes in Patients With Coronary Artery Disease

牵拉压力梯度对冠状动脉疾病患者报告结果的影响

3. Prospective Randomized Trial Evaluating Clinical Outcomes of Angiography-Based Fractional Flow Reserve Guidance Versus Wire-Based Fractional Flow Reserve Guidance: The PROVISION Trial

对比基于血管造影的血流储备分数引导VS基于导线的血流储备分数引导的临床结果:一项前瞻性随机试验PROVISION

4. Multicenter Prospective Assessment of Coronary Microvascular Dysfunction: Primary Results of the FlowLab Study

冠状动脉微血管功能障碍的多中心前瞻性评估:FlowLab 研究的主要结果

5. Coronary Physiological Indices to Evaluate Myocardial Ischemia in Patients With Aortic Valve Stenosis Undergoing Valve Replacement: The COMIC-AS Study

评估接受瓣膜置换术的主动脉瓣狭窄患者中心肌缺血的冠脉生理指标:COMIC-AS 研究



TCT WorldLink Forum: Best Global Research in Percutaneous Coronary Intervention

北京时间:20:30-21:45

1. Traditional Versus Distal Radial Access for Coronary Diagnostic and Revascularization Procedures: Final Results of the TENDERA Multicenter, Randomized Controlled Study

冠状动脉诊断和血运重建手术的常规与远端桡动脉通路:TENDERA 多中心、随机对照研究最终结果

2. Impact of Small or Non-Small Vessel Disease to Drug-Coated Balloon Angioplasty for the Treatment of De Novo Coronary Artery Lesions: Insights From the REC-CAGEFREE I Trial

小血管或非小血管疾病对药物涂层球囊血管成形术治疗新发冠状动脉病变的影响:来自 REC-CAGEFREE I试验的见解

3. Final Results of the Novel Healing-Targeted DES With Synchronized Antiproliferative Drug Delivery to Target Smooth Muscle Cell Proliferation After DES Implantation in Coronary Artery Disease: 5-Year Results of the PIONEER III Trial

新型愈合靶向药物洗脱支架(DES)与同步抗增殖药物释放相结合,在冠状动脉疾病中DES植入后针对平滑肌细胞增殖的最终结果:PIONEER III试验的5年结果

4. Magnesium-Based Resorbable Scaffold vs Permanent Metallic Sirolimus-Eluting Stent in Patients With ST-Segment Elevation Myocardial Infarction: Final 5-Year Results of the MAGSTEMI Randomized Controlled Trial

ST段抬高型心肌梗死患者镁基可吸收支架VS永久性金属西罗莫司洗脱支架:MAGSTEMI随机对照试验的最终5 年结果

5. From ARC-HBR and PRECISE-DAPT to PRECISE-2: Development and Validation of a Novel Universal Bleeding Risk Score

从ARC-HBR和PRECISE-DAPT到PRECISE-2:新型通用出血风险评分的开发和验证

2

心力衰竭系列之全球最佳研究

10月28日:

TCT WorldLink Forum: Best Global Research in Shock and Mechanical Circulatory Support

北京时间:14:30-15:45

1. Real-Time Catheter-Based MVO Detection in STEMI: Final Results from the MOCA I Study

STEMI中基于导管的实时 MVO 检测:MOCA I 研究的最终结果

2. Single Catheter Primary PErcutaneous Coronary Intervention MEthoD in Patients With ST Elevation MYocardial Infarction: SPEEDY PCI Study

ST段抬高型心肌梗死患者的单导管经皮冠状动脉介入治疗MEthoD:SPEEDY PCI研究

3. Impact of Microaxial Flow Pump on Central Hemodynamics and Use of Vasoactive Drugs During Intensive Care After Infarct-Related Cardiogenic Shock: A Secondary Analysis of the DanGer Shock Trial

微型轴流泵对梗死相关心源性休克患者在重症监护期间中枢血流动力学和血管活性药物使用的影响:DanGer Shock试验的二次分析

4. Microaxial Flow Pump Use and Renal Outcomes in Cardiogenic Shock: An Analysis of the DanGer Shock Trial

微型轴流泵的使用和心源性休克的肾脏结局:DanGer Shock试验分析

5. Impact of Bleeding Complications on Clinical Outcomes in Patients Undergoing Impella Support in Cardiogenic Shock

出血并发症对接受Impella治疗的心源性休克患者临床结局的影响

6. Mechanical Circulatory Support of High-Risk PCI With a Novel, Low-Profile pMCS: First Results of the Impella ECP Pivotal Study

在高危PCI中使用新型低轮廓脉冲式机械循环支持系统(pMCS)的机械循环支持:Impella ECP关键研究的首批结果。

3

结构性心脏病系列之全球最佳研究


TCT WorldLink Forum: Best Global Research in Transcatheter Aortic Valve Replacement

北京时间:13:00-14:15

1. Short- and Long-Term Effect of Cerebral Embolic Protection Device on New Brain Lesions Following Transcatheter Aortic-Valve Replacement: The Sentinel Registry (Sentinel)

脑栓塞保护装置对经导管主动脉瓣置换术后新发脑部病变的短期和长期影响:Sentine登记研究(Sentinel)

2. Prospective Validation of a Pre-Specified Algorithm for the Management of Conduction Disturbances Following Transcatheter Aortic Valve Replacement

经导管主动脉瓣置换术后传导障碍的预先指定算法的前瞻性验证

3. Antiplatelet Therapy and All-Cause Mortality After Transcatheter Aortic Valve Replacement: The TRITAVI Registry

经导管主动脉瓣置换术后的抗血小板治疗和全因死亡率:TRITAVI 注册研究

4. The Coronary AccEss After TAVR (CAvEAT) Registry: An International, Multicenter Prospective Registry of Coronary Access After TAVR

TAVR后冠状动脉入路(CAvEAT)登记研究:TAVR后冠状动脉通路的国际、多中心前瞻性研究

5. DISCORDANCE TAVR: Standardized Invasive Hemodynamics for Elevated Gradients Post TAVR

DISCORDANCE TAVR:TAVR后压力梯度升高的标准化侵入性血流动力学



TCT WorldLink Forum: Best Global Research in Tricuspid Transcatheter Edge-to-Edge Repair

北京时间:15:30-16:45

1. TRILUMINATE Pivotal Trial: Outcomes in the Primary Analysis Population vs Subsequent Enrollment

TRILUMINATE 关键试验:人群VS后续入组的结果分析

2. TriClip Outcomes in Patients With CIED Leads Results From the TRILUMINATE Pivotal Trial

CIED导联患者的TriClip结果:TRILUMINATE关键试验的结果

3. Multicentric Randomized Evaluation of Transcatheter Edge-to-Edge Repair for Severe Isolated Tricuspid Regurgitation: The TRI-FR Trial: Evolution Over Time of Transthoracic Echocardiography Parameters

经导管缘对缘修复治疗严重孤立性三尖瓣反流的多中心随机评估:TRI-FR试验:经胸超声心动图参数随时间变化

4. Transcatheter Leaflet Repair for Tricuspid Regurgitation: 1-Year Results From the PASTE Registry

经导管瓣叶修复治疗三尖瓣反流:PASTE登记的1年结果

5. Impact of Pulmonary Hypertension on Outcomes After Transcatheter Tricuspid Valve Edge-to-Edge Repair: Insights Into the EuroTR Registry

肺动脉高压对经导管三尖瓣缘对缘修复后结果的影响:EuroTR登记研究



TCT WorldLink Forum: Best Global Research in Transcatheter Mitral Valve Intervention

北京时间:17:00-18:15

1. Temporal Changes in Procedural Success and Clinical Outcome of TEER by Mechanism of Mitral Regurgitation: Analysis of the STS/TVT Registry

二尖瓣反流机制对TEER手术成功和临床结果的时间性变化:STS/TVT登记分析。

2. M-TEER for Moderate to Severe FMR in Symptomatic Heart Failure: Comparison of RESHAPE-HF2 Trial Results With Outcomes in MITRA-FR and COAPT

M-TEER治疗中度至重度FMR的症状性心力衰竭结果:RESHAPE-HF2试验结果与MITRA-FR和COAPT结果的比较

3. Impact of MitraClip on Hospitalization Rates in Symptomatic Patients With Heart Failure and Moderate to Severe Functional Mitral Regurgitation: Insights From RESHAPE-HF2

MitraClip对有症状的心力衰竭和中度至重度功能性二尖瓣反流患者住院率的影响:RESHAPE-HF2

4. Mitral TEER Versus Redo-Surgery in Primary MR Patients With Failed Surgical Valve Repair: Insights From the International Multi-Center REDO-MR Registry

M-TEERvs二次手术治疗瓣膜修复失败的原发性MR患者的疗效:来自国际多中心REDO-MR登记处的见解

5. Mid-Term Outcomes of Mitral Valve in Valve Therapy in the United States

美国瓣膜治疗二尖瓣的中期结局


延伸阅读

TCT 2024|详细日程速览!26项LBCT/LBCS临床研究即将重磅发布!


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