编辑之选：食品中功能活性化合物的筛选与预测

食品是一种复杂的物质，它既含有营养物质，又含有功能性/生物活性化合物，如黄酮、色素、多酚、多糖、低聚糖、抗氧化剂、酶等。此外，食物在消化过程中会产生更多的生物活性化合物。最典型的生物活性胃肠道产物之一是生物活性肽。所有这些功能性/生物活性化合物在人类健康甚至某些疾病中发挥着关键作用。

因此，高效发现这些功能/生物活性化合物，特别是高通量的发现或筛选，变得非常重要。信息科学技术和组学（基因组学、蛋白质组学、代谢组学、风味组学等）、高通量技术、虚拟/计算预测技术的迅速发展，促进了食品中功能/生物活性化合物的高效发现和创新。本期特刊将重点介绍筛选、预测和设计食品中功能性和/或生物活性化合物的新技术，包括高通量方法、虚拟/计算策略，信息学手段、体外、或体内的生物活性测定，及分子机制的阐明等新技术。

The screening and prediction of functional/bioactive compounds in foods: Editorial; how to efficiently discover functional/bioactive compounds in foods?

The effect of Spirulina sauce, as a functional food, on cardiometabolic risk factors, oxidative stress biomarkers, glycemic profile, and liver enzymes in nonalcoholic fatty liver disease patients: A randomized double-blinded clinical trial

Metabolomics study of Angelica sinensis (Oliv.) Diels on the abnormal uterine bleeding rats by ultra-performance liquid chromatography–quadrupole–time-of-flight mass spectrometry analysis

Polysaccharides isolated from Bangia fuscopurpurea induce apoptosis and autophagy in human ovarian cancer A2780 cells

Flavonoid-enriched extract from Millettia speciosa Champ prevents obesity by regulating thermogenesis and lipid metabolism in high-fat diet–induced obese C57BL/6 mice

Comprehensive lipidomic analysis of the lipids extracted from freshwater fish bones and crustacean shells

Influenza virus entry and replication inhibited by 8-prenylnaringenin from Citrullus lanatus var. citroides (wild watermelon)

Zebrafish obesogenic test identifies anti-adipogenic fraction in Moringa oreifera leaf extracts

The significance and potential of functional food ingredients for control appetite and food intake

Evaluation of Nano-curcumin effects against Tartrazine-induced abnormalities in liver and kidney histology and other biochemical parameters

Yogurt fortification by microencapsulation of beetroot extract (Beta vulgaris L.) using maltodextrin, gum arabic, and whey protein isolate

Comparison of the effect of saffron, crocin, and safranal on serum levels of oxidants and antioxidants in diabetic rats: A systematic review and meta-analysis of animal studies

LC/MS analysis of mushrooms provided new insights into dietary management of diabetes mellitus in rats

Miao sour soup influences serum lipid via regulation of high-fat diet-induced intestinal flora in obese rats

Curcumin-loaded cockle shell-derived calcium carbonate nanoparticles ameliorates lead-induced neurotoxicity in rats via attenuation of oxidative stress

Isolation of a potential probiotic strain Bacillus amyloliquefaciens LPB-18 and identification of antimicrobial compounds responsible for inhibition of food-borne pathogens

Prediction of winter wheat leaf chlorophyll content based on VIS/NIR spectroscopy using ANN and PLSR

Neuroprotective effects of a novel peptide from Lignosus rhinocerotis against 6-hydroxydopamine-induced apoptosis in PC12 cells by inhibiting NF-κB activation

Panax ginseng abuse exhibits a pro-inflammatory effect by activating the NF-κB pathway

Effects of Allium roseum L. extracts on the proliferation and the differentiation of the acute myeloid leukemia cell line U937

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