慢阻肺月报202406
文摘
科学
2024-06-15 23:33
上海
JAMA. 2024 May 19; PMID: 38762800
Bisoprolol in Patients With Chronic Obstructive Pulmonary Disease at High Risk of Exacerbation: The BICS Randomized Clinical Trial.Graham Devereux, Seonaidh Cotton, Mintu Nath, et alNew England Journal of Medicine. 2024 May 20; PMID: 38767614Dupilumab for COPD with Blood Eosinophil Evidence of Type 2 Inflammation.Surya P Bhatt, Klaus F Rabe, Nicola A Hanania, et al“孤证不立”,现在有两项设计相仿的研究得出了一致结论,可信度大大提高了。European Respiratory Journal. 2024 May 29; PMID: 38811045Inhaled Treprostinil in Pulmonary Hypertension Associated with COPD: PERFECT study results.Steven D Nathan, Rahul Argula, Maria G Trivieri, et al只要设计合理、执行严格,即便是显示治疗失败的研究也有其价值,某种程度上甚至价值更大。
New England Journal of Medicine. 2024 May 19; PMID: 38767248Early Diagnosis and Treatment of COPD and Asthma - A Randomized, Controlled Trial.Shawn D Aaron, Katherine L Vandemheen, G Alex Whitmore, et al在加拿大医疗系统背景下,COPD疾病筛查-按照指南的治疗能减少医疗系统负担。
New England Journal of Medicine. 2024 May 19; PMID: 38767252Implications of Race Adjustment in Lung-Function Equations.James A Diao, Yixuan He, Rohan Khazanchi, et alChest. 2024 May 24; PMID: 38797279Small airways obstruction and mortality: Findings from the UK Biobank.Valentina Quintero Santofimio, Ben Knox-Brown, James Potts, et al说明的是相关性,而不是因果关系,从而也不能推导出干预SAO能降低死亡风险。
American Journal of Respiratory and Critical Care Medicine. 2024 Jun 6; PMID: 38843116Association of Ground Glass Opacities with Systemic Inflammation and Progression of Emphysema.Spyridon Fortis, Junfeng Guo, Prashant Nagpal, et al