慢阻肺月报202404

文摘   科学   2024-04-21 06:24   浙江  


American Journal of Respiratory and Critical Care Medicine. 2024 Mar 19; PMID: 38502541

RSV-related Community COPD Exacerbations and Novel Diagnostics: A Binational Prospective Cohort Study.
Dexter J Wiseman, Ryan S Thwaites, Andrew I Ritchie, et al

不同于以往认为RSV下呼吸道感染往往发生在婴幼儿和免疫抑制人群,新近的流行病学调查在体弱老年人和慢阻肺人群中也观察到RSV感染疾病负担的升高,本文则增加了AECOPD患者中RSV感染的新数据。GOLD 2024报告中新增了RSV疫苗的推荐,本文也验证了在疫苗接种人群中检测RSV感染的血清学方法。
GOLD 2024为何新增RSV疫苗接种推荐?
mRNA RSV疫苗研发最新进展

American Journal of Respiratory and Critical Care Medicine. 2024 Mar 20; PMID: 38507607
The Effect of Chronic Altitude Exposure on COPD Outcomes in the SPIROMICS Cohort.
Rajat Suri, Daniela Markovic, Han Woo, et al


Chest. 2024 Mar 25; PMID: 38537688
Changes in Spirometry Interpretative Strategies: Implications for Classifying COPD and Predicting Exacerbations.
J Henry Brems, Aparna Balasubramanian, Sarath Raju, et al


American Journal of Respiratory and Critical Care Medicine. 2024 Apr 12; PMID: 38607551
Application of the ERS/ATS Spirometry Standards and Race-Neutral Equations in the COPDGene Study.
Enrico Schiavi, Min Hyung Ryu, Leonardo Martini, et al


American Journal of Respiratory and Critical Care Medicine. 2024 Apr 10; PMID: 38597717
Severity of Airflow Obstruction Based on FEV 1 /FVC vs FEV 1 % of Predicted in the General US Population.
Helena Backman, Lowie E G W Vanfleteren, David M Mannino, et al

本月有3篇肺功能方面的文章。肺功能诊断和分级标准一定是要有临床相关性数据为主要依据,才有疾病诊断、预后预测价值,相应地采取临床治疗策略才师出有名。

American Journal of Respiratory and Critical Care Medicine. 2024 Apr 16; PMID: 38626356
Lung Tissue Multi-Layer Network Analysis Uncovers the Molecular Heterogeneity of COPD.
Nuria Olvera, Jon Sánchez-Valle, Iker Núñez-Carpintero, et al

非常有意思的是同样的表型可以有不同的内型。随着检测手段和信息分析技术的进步,COPD的评估和治疗也逐渐显露出精准治疗的曙光。

慢阻肺手抄本
To cure technically, to comfort psychologically, to relieve morally