慢阻肺月报202305
文摘
科学
2023-05-21 00:20
上海
![]()
American Journal of Respiratory and Critical Care Medicine. 2023 May 16; PMID: 37192443
Serum Interleukin-8 as a Determinant of Response to PDE4 Inhibition in Chronic Obstructive Pulmonary Disease.Mirco Govoni, Michele Bassi, Debora Santoro, et al![]()
IL-8低水平患者PDE4抑制剂的疗效更佳，期待有另一个独立数据集能够重复同样的结果。高质量的数据+分析/AI将开启慢阻肺“精准治疗”的新时代！Thorax. 2023 May 5; PMID: 37147124Short-term air pollution exposure and exacerbation events in mild to moderate COPD: a case-crossover study within the CanCOLD cohort.Bryan A Ross, Dany Doiron, Andrea Benedetti, et al![]()
即便是轻中度COPD，空气污染也会带来不利影响。空气污染和肺健康是近年的研究热点，今年ERS的主题即为Pollution, Climate change and Sustainable developments。American Journal of Respiratory and Critical Care Medicine. 2023 May 9; PMID: 37159910Causes of and Clinical Features Associated with Death in Tobacco Cigarette Users by Lung Function Impairment.Wassim W Labaki, Tian Gu, Susan Murray, et al![]()
European Respiratory Journal. 2023 Apr 20; PMID: 37080569A novel thiol-saccharide mucolytic for the treatment of muco-obstructive lung diseases.Annalisa Addante, Wilfred Raymond, Irina Gitlin, et al![]()
这是和NAC作用机制属于同一类的祛痰药，体外和动物实验显示出了良好疗效和前景，接下来有待漫长的临床试验摸索剂量和验证疗效及安全性。
