目前有研究显示，神经干细胞能够自我更新、分化并迁移，有助于修复突触和神经元损伤，减少病理性蛋白如淀粉样蛋白和tau蛋白的积累，以及减轻神经炎症。
同时，自噬作用在维持神经干细胞功能和脑内稳态中起着关键作用。此外，针对脊髓损伤的治疗，干细胞疗法结合三维生物打印技术成为了目前的研究焦点，如通过打印精确的细胞支架来修复受损的神经电路，促进功能恢复。这些干细胞疗法研究为开发新的神经系统疾病治疗方法提供了方向。
为此，选择本刊学者2023-2024年发表的细胞外囊泡在神经系统疾病中作用机制的相关综述文章3篇，推荐读者阅读。
(1)Neural stem cells promote neuroplasticity: a promising therapeutic strategy for the treatment of Alzheimer's disease
神经干细胞促进神经可塑性：治疗阿尔茨海默病的前景广阔的治疗策略
Jun Chang 1, Yujiao Li 1, Xiaoqian Shan 1, Xi Chen 1, Xuhe Yan 1, Jianwei Liu 2, Lan Zhao 1
1 First Teaching Hospital of Tianjin University of Traditional Chinese Medicine; National Clinical Research Center for Chinese Medicine Acupuncture and Moxibustion, Tianjin, China.
2 Tianjin University of Traditional Chinese Medicine, Tianjin, China.
引用本文：
Chang J, Li Y, Shan X, et al. Neural stem cells promote neuroplasticity: a promising therapeutic strategy for the treatment of Alzheimer's disease. Neural Regen Res. 2024;19(3):619-628.
正文链接：
https://journals.lww.com/nrronline/fulltext/2024/03000/neural_stem_cells_promote_neuroplasticity__a.37.aspx
(2) Autophagy in neural stem cells and glia for brain health and diseases
神经干细胞和神经胶质细胞中的自噬作用对大脑健康和疾病的影响
Aarti Nagayach, Chenran Wang
Department of Cancer Biology, University of Cincinnati College of Medicine, Cincinnati, OH, USA.
引用本文：
Nagayach A, Wang C. Autophagy in neural stem cells and glia for brain health and diseases. Neural Regen Res. 2024;19(4):729-736.
正文链接：
https://journals.lww.com/nrronline/fulltext/2024/04000/autophagy_in_neural_stem_cells_and_glia_for_brain.15.aspx
(3) The combined application of stem cells and three-dimensional bioprinting scaffolds for the repair of spinal cord injury
干细胞与三维生物打印支架在脊髓损伤修复中的联合应用
Dingyue Ju , Chuanming Dong 1, 2
1 Department of Anatomy, Medical College of Nantong University, Nantong, Jiangsu Province, China.
2 Key Laboratory of Neuroregeneration of Jiangsu and Ministry of Education, Co-innovation Center of Neuroregeneration, Nantong University, Nantong, Jiangsu Province, China.
引用本文：
Ju D, Dong C. The combined application of stem cells and three-dimensional bioprinting scaffolds for the repair of spinal cord injury. Neural Regen Res. 2024;19(8):1751-1758.
正文链接：
https://journals.lww.com/nrronline/fulltext/2024/08000/the_combine
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