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This study confirms that Cutibacterium acnes bacteria are capable of harboring phage pseudolysogens and suggests that this phenomenon plays a role in bacterial superinfection resistance. This mechanism may be conferred by the expression of phage proteins while the phage persists within the host in the pseudolysogenic state. This parameter must be considered in future endeavors for the efficacious application of C. acnes phage-based therapeutics.
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Contents
本期共发表13篇文章，包括10篇原创论文 (Original Article)，1篇综述(Review)，1篇视角 (Perspective), 1篇简短报告 (Short Report)。本期作者来自全球8个国家：美国、加拿大、德国、荷兰、日本、瑞士、芬兰、希腊。
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原创论文 Original Article
1. Assessing fecal metaproteomics workflow and small protein recovery using DDA and DIA PASEF mass spectrometry
作者：加拿大渥太华大学张旭博士团队
http://dx.doi.org/10.20517/mrr.2024.21
2. Effect of protein modification in synbiotic infant formula on probiotic metabolic activity and bacterial composition in an infant gut-model
作者：德国海普股份有限公司海普股份有限公司Monika Schaubeck博士团队
http://dx.doi.org/10.20517/mrr.2024.13
3. Omics-based analysis of Akkermansia muciniphila cultivation in food-grade media
作者：荷兰瓦赫宁恩大学Willem M. de Vos教授团队
http://dx.doi.org/10.20517/mrr.2024.06
4. Associations between intestinal lactic acid bacteria species and feeding habits of zoo animals
作者：日本国家先进工业科学技术研究院Masanori Horie博士团队
http://dx.doi.org/10.20517/mrr.2024.08
5. Supplementation with a cranberry extract favors the establishment of butyrogenic guilds in the human fermentation SHIME system
作者：加拿大拉瓦尔大学Valentina Cattero博士团队
http://dx.doi.org/10.20517/mrr.2024.17
6. Pangenomic analysis identifies correlations between Akkermansia species and subspecies and human health outcomes
作者：美国加州州立大学Raphael H. Valdivia博士团队
http://dx.doi.org/10.20517/mrr.2024.09
7. A pilot case-control study on the fecal microbiota of pediatric functional abdominal pain-not otherwise specified and the role of early life stress
作者：瑞士苏黎世联邦理工学院Christophe Lacroix教授团队
http://dx.doi.org/10.20517/mrr.2023.75
8. Probing interspecies metabolic interactions within a synthetic binary microbiome using genome-scale modeling
作者：美国奥本大学王进教授团队
http://dx.doi.org/10.20517/mrr.2023.70
9. Analysis of the fermentation kinetics and gut microbiota modulatory effect of dried chicory root reveals the impact of the plant-cell matrix rationalizing its conversion in the distal colon
作者：荷兰瓦赫宁恩大学Willem M. de Vos教授团队
http://dx.doi.org/10.20517/mrr.2024.04
10. Putative pseudolysogeny-dependent phage gene implicated in the superinfection resistance of Cutibacterium acnes
作者：美国加州大学洛杉矶分校Stephanie Wottrich博士团队
http://dx.doi.org/10.20517/mrr.2023.42
综述 Review
Probiotics, prebiotics, synbiotics, and other microbiome-based innovative therapeutics to mitigate obesity and enhance longevity via the gut-brain axis
作者：加拿大麦吉尔大学Satya Prakash博士团队
http://dx.doi.org/10.20517/mrr.2024.05
视角 Perspective
Akkermansia beyond muciniphila - emergence of new species Akkermansia massiliensis sp. nov.
作者：美国IFF公司Ashley A Hibberd博士团队
http://dx.doi.org/10.20517/mrr.2024.28
简短报告 Short Report
Faecalibacterium prausnitzii A2-165 metabolizes host- and media-derived chemicals and induces transcriptional changes in the colonic epithelium in GuMI human gut microphysiological system
作者：美国麻省理工学院张建波博士团队
http://dx.doi.org/10.20517/mrr.2024.14
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