第一步：选择参考文献
我们选用Nature子刊 Nature Communications 2024年1月发表的头颈肿瘤研究文章作为范例：
范例文献:Wu, J., Yang, L., Matsushita, Y. et al. Spatial mapping reveals human head and neck cancer microenvironment features associated with treatment response. Nat Commun 15, 424 (2024).
第二步：AI辅助解构引言
引言解构的具体Prompt
Please analyze the introduction section of this head and neck cancer research paper. For each paragraph:1. Identify the specific function (e.g., background, problem statement, research gap)2. List all key statistical data and their citations3. Extract transition sentences between paragraphs4. Note any rhetorical devices or writing techniques used5. Create a detailed outline showing:- Main argument of each paragraph- Supporting evidence used- Logical connections between paragraphsPlease format your analysis with clear headings and bullet points.
选定文献的引言结构分析结果
开篇点明头颈部鳞状细胞癌（HNSCC）的流行病学数据 引用具体数据：全球每年超过90万新发病例，死亡率超过50% 过渡句：强调了解肿瘤微环境（TME）的重要性
介绍已有的研究方法（单细胞测序技术） 列举关键发现：发现了多种免疫细胞亚群 引用最新研究数据：确定了6种主要免疫细胞类型 过渡句：指出现有方法的局限性
介绍空间转录组学技术的优势 具体数据：可以分析超过1000个基因的表达 强调该技术在肿瘤异质性研究中的应用价值
明确提出研究目标 介绍研究方法
预期研究成果
第三步：基于框架构建新引言
准备工作
收集用于新引言的参考文献：
核心参考文献：
"Spatial transcriptomics of human head and neck cancer reveals novel immune microenvironment patterns" (Cancer Cell, 2023)
"Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of head and neck cancer" (Nature Communications, 2023)
写作Prompt设计
Please help me write an introduction for a head and neck cancer research paper following this specific structure:1. First paragraph:- Start with the latest global HNSCC epidemiological data from [引用具体文献]- Emphasize the specific challenges in treatment- End with the importance of tumor microenvironment2. Second paragraph:- Review current single-cell sequencing findings in HNSCC- Use data ONLY from [引用具体文献]- Focus on immune cell populations discovered- Highlight current limitations3. Third paragraph:- Introduce spatial transcriptomics technology- Cite specific advantages from [引用具体文献]- Connect to HNSCC research needs4. Fourth paragraph:- State research objectives- Outline methodology- Present expected impactRequirements:1. Use ONLY data and findings from the provided references2. Maintain precise scientific language3. Include proper citations for every factual statement4. Ensure logical flow between paragraphs
输出的修改要点
数据准确性检查：
核对每个数字与原文献
确保引用标注正确
更新最新统计数据
逻辑连贯性强化：
增加段落间过渡句
强化论证逻辑
突出研究创新点
第四步：降低AI痕迹
具体修改方法
句式多样化：
原句："Recent studies have shown that..." 修改为："Emerging evidence suggests that..." 变化："Increasingly, researchers have recognized that..."
检查专业术语使用频率 适当增加领域特有的简写 保持术语使用的一致性
原句："exactly 87.5% of cases..." 修改为："approximately 88% of cases..." 避免过于精确的表述
