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Jasmonate signaling pathway confers salt tolerance through a NUCLEAR FACTOR-Y trimeric transcription factor complex in Arabidopsis
Abstract
背景+问题：Jasmonate (JA) is a well-known phytohormone essential for plant response to biotic stress. Recently, a crucial role of JA signaling in salt resistance has been highlighted; however, the specific regulatory mechanism remains largely unknown.
NF-Y转录因子复合体与JAZ8：In this study, we found that the NUCLEAR FACTOR-Y (NF-Y) subunits NF-YA1, NF-YB2, and NF-YC9 form a trimeric complex that positively regulates the expression of salinity-responsive genes, whereas JASMONATE-ZIM DOMAIN protein 8 (JAZ8) directly interacts with three subunits and acts as the key repressor to suppress both the assembly of the NF-YA1-YB2-YC9 trimeric complex and the transcriptional activation activity of the complex.
作用机制：When plants encounter high salinity, JA levels are elevated and perceived by the CORONATINE INSENSITIVE (COI) 1 receptor, leading to the degradation of JAZ8 via the 26S proteasome pathway, thereby releasing the activity of the NF-YA1-YB2-YC9 complex, initiating the activation of salinity-responsive genes, such as MYB75, and thus enhancing the salinity tolerance of plants.
摘 要
茉莉酸JA是一个参与植物响应生物胁迫的植物激素。最近，有研究报道了JA信号转导在植物耐盐性中发挥重要作用，但背后的调控机制还不清楚。本文中，作者发现NF-Y亚基NF-YA1、NF-YB2和NF-YC9能够形成一个三聚复合体，正调控盐胁迫响应基因的表达，而JAZ8能够直接与这三个亚基互作，并且作为关键的抑制子能够同时抑制NF-YA1-YB2-YC9三聚复合体的组装以及该复合体的转录激活活性。当植物遭遇高盐胁迫时，JA水平升高并且被COI1受体感知，从而导致JAZ8被26S蛋白酶体途径降解，进而释放了NF-YA1-YB2-YC9复合体的活性，使得MYB75等盐胁迫响应基因能够被转录激活，最终增强了植物的耐盐性。
李长江博士和傅缨教授为共同通讯作者，博士研究生李星和李长江博士为论文的共同第一作者，该研究得到国家自然科学基金的资助。
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