慢性阻塞性肺病(COPD)患者肺部和小气道实质破坏,造成持续气流限制。常见的并发症包括心血管疾病、慢性肾病、骨质疏松症和肌肉减少症。严重影响患者生活质量、发病率、住院率和死亡率。研究表明,维生素K2有助于防治慢性阻塞性肺病的多种并发症。
图:维生素K2缺乏会导致心血管疾病、慢性肾病、
骨质疏松症、肌肉减少症和慢性阻塞性肺病
【文献来源】
[1] Piscaer I, Janssen R, Franssen FME, Schurgers LJ, Wouters EFM. The Pleiotropic Role of Vitamin K in Multimorbidity of Chronic Obstructive Pulmonary Disease. J Clin Med. 2023 Feb 5;12(4):1261.
[2] Shen T, Bimali M, Faramawi M, Orloff MS. Consumption of Vitamin K and Vitamin A Are Associated With Reduced Risk of Developing Emphysema: NHANES 2007–2016. Front. Nutr. 2020, 7, 47.
[3] Piscaer I, van den Ouweland JMW, Vermeersch K, Reynaert NL, Franssen FME, Keene S, Wouters EFM, Janssens W, Vermeer C, Janssen R. Low Vitamin K Status Is Associated with Increased Elastin Degradation in Chronic Obstructive Pulmonary Disease. J. Clin. Med. 2019, 8, 1116.
作者 | 周建烈
编辑 | 林瑞霞
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