热烈恭贺创腾科技合作伙伴
三迭纪
和BioNTech达成研究合作与平台技术许可协议，通过3D打印药物技术开发口服RNA药物
三迭纪将在合作中充分运用3D打印药物技术的专业知识，进行创新口服制剂的设计，旨在优化RNA药物透过胃肠道黏膜的递送，减少RNA药物在胃肠道的降解，并将RNA药物递送至胃肠道潜在的最佳吸收部位。三迭纪能够为药物制剂创建独特的外部和内部结构，如多层片、多腔室设计等，进而优化创新RNA药物的递送。
“我们深感荣幸能够与BioNTech开展合作，BioNTech是一家通过创新疗法为患者健康带来变革的领先公司。” 三迭纪创始人、CEO成森平博士表示，“我们相信，此次合作有望成为3D打印技术推动口服RNA药物发展的里程碑，并为口服大分子药物的开发树立新的标杆。我们双方将紧密合作，致力于携手在RNA药物口服递送领域取得突破。”
根据协议条款，三迭纪将获得1千万美元的首付款，并有望获得总金额超过12亿美元的产品开发、注册和商业化里程碑付款，以及未来潜在的分级销售特许使用费。
右滑查看中文
NANJING, China, July 23, 2024 – Triastek, Inc. ("Triastek"), a global leader in 3D printing pharmaceuticals, today announced that it has entered into a research collaboration and platform technology license agreement with BioNTech SE ("BioNTech"), a next generation immunotherapy company pioneering novel therapies for cancer and other serious diseases. Under the agreement, the companies will develop RNA therapeutics for oral delivery based on 3D printing technology. The collaboration aims to provide groundbreaking therapies to address unmet medical needs in an easy to administer oral formulation.
Triastek will contribute to the collaboration its expertise in innovative oral tablet designs made possible by 3D printing aimed at optimizing delivery of RNA therapeutics across the gastrointestinal mucosa, minimizing degradation in the gastrointestinal tract, and delivering RNA therapeutics to the portion of the gastrointestinal tract where absorption will potentially be the greatest. Triastek's ability to create tablet structures with unique external and internal tablet geometries, including multiple-layer and multi-compartment designs, will be leveraged, aiming to optimize delivery of novel RNA therapeutics.
"We are immensely honored to announce our collaboration with BioNTech, a leader in revolutionizing patient care with transformative medicines," stated Dr. Senping Cheng, Founder, and CEO of Triastek. "We believe this collaboration stands as a promising milestone in advancing oral RNA therapeutics using 3D printing technology and aims to set new benchmarks in the development of large molecule oral drugs. We are committed to working diligently together to make breakthroughs in oral delivery of RNA therapeutics."
Under the terms of the agreement, Triastek will receive an upfront payment of $10 million, and will be eligible to receive development, regulatory and commercial milestone payments potentially totaling over $1.2 billion as well as tiered royalties on potential future product sales.
本文转载于三迭纪Triastek
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