2024 AHA热点聚焦:7场特色科学研究专场,29项重磅研究引领学术前沿

学术   2024-10-12 18:30   中国  

11月16日-18日,2024年美国心脏协会科学年会(2024 AHA)将在芝加哥以线下+线上结合的方式盛大召开。日前,大会议程已经公布,会议期间共设置7特色科学研究Featured Science)专场29项研究一起先睹为快吧!




FS.01 特色科学:血脂风险管理新方法

北京时间:11月17日 02:30~03:45


LIBerate-OLE - Long-term Efficacy of Lerodalcibep in 1,468 Patients at Very High and High Risk for CVD in the 72 week Open-Label Extension Trial (LIBerate-OLE)

LIBerate-OLE开放标签扩展试验:在1468例心血管高危患者中,探究Lerodalcibep的长期疗效(72周


LIBerate-HeFH_OLE - Efficacy and Safety of Lerodalcibep, a Third Generation PCSK9 Inhibitor, in 703 Heterozygous Familial Hypercholesterolemia Subjects in the Open Label Extension Trial (LIBerate-HeFH_OLE)
LIBerate-HeFH_OLE开放标签扩展试验:在703例杂合子家族性高胆固醇血症患者中,探究第三代PCSK9抑制剂Lerodalcibep的疗效和安全性


PALISADE: A Phase 3 Study to Assess the Efficacy and Safety of Plozasiran in adults with Genetically or Clinically-Defined Familial Chylomicronemia Syndrome (FCS) at high risk of Acute Pancreatitis (AP)
PALISADE 3期试验:在急性胰腺炎(AP)高风险的遗传或临床定义的家族性乳糜小铁血症综合征(FCS)成人患者中评估plzasiran的疗效和安全性


YELLOW III - Transcriptomic Signatures and Predictors of Evolocumab Added to Maximum Statin Therapy Based on Intra-Coronary Plaque Characteristics: YELLOW III Study
YELLOW III试验:基于冠状动脉内斑块特征,在最大剂量他汀类药物治疗中加入依洛尤单抗的转录组特征和预测因素




FS.02 特色科学:健康技术与临床试验的未来

北京时间:11月17日 02:30~03:45


DELIVER - Natural Language Processing to Adjudicate Heart Failure Hospitalizations in Global Clinical Trials (DELIVER)

DELIVER试验:在全球临床试验中,使用自然语言处理判断心衰住院情况


MAPS-LLM - Manual versus AI-Assisted Clinical Trial Screening using Large-Language Models (MAPS-LLM)
MAPS-LLM试验:人工 vs. 人工智能(大语言模型),来进行临床试验筛选


MyoMobile - Personalized App-Based Coaching Improves Physical Activity in Patients With HFpEF Compared to Standard Care – A Randomized Parallel Group Trial (MyoMobile Study)
MyoMobile随机平行组试验:与标准护理相比,基于应用APP的个性化指导,可改善射血分数保留型心衰(HFpEF患者的体力活动


mTECH-Rehab - Impact of Technology-Enabled Home-Based Cardiac Rehabilitation on Functional Status and Cardiovascular Health Metrics: The American Heart Association Health Technology Network mTECH-Rehab Randomized Controlled Trial (mTECH-Rehab)
AHA健康技术网络mTECH-Rehab随机对照试验:基于家庭的技术支持的心脏康复对功能状态和心血管健康指标的影响




FS.03 特色科学:更接近峰值的新型HFpEF治疗方法

北京时间:11月17日 21:00~22:15


Effect of finerenone on a hierarchical composite endpoint analyzed using win statistics in patients with heart failure and mildly reduced or preserved ejection fraction: A prespecified analysis of FINEARTS-HF

FINEARTS-HF试验预先设定的分析:在射血分数轻度降低衰(HFmrEF)或HFpEF患者中,使用win统计法分析非奈利酮对分层复合终点事件的影响


Efficacy and safety of finerenone in patients with heart failure and mildly reduced or preserved ejection fraction: A prespecified sex-specific analysis of the FINEARTS-HF trial
FINEARTS-HF试验预先设定的性别特异性分析:在HFmrEF/ HFpEF患者中,探究非奈利酮的疗效和安全性


Finerenone and Risk of Hyperkalemia in Patients with Heart failure with Mildly Reduced or Preserved Ejection Fraction (FINEARTS-HF)
FINEARTS-HF试验:在HFmrEF/ HFpEF患者中,探究非奈利酮应用与高钾血症风险之间的关系


Effects of Tirzepatide on Cardiorenal End-Organ Damage in Heart Failure and Preserved Ejection Fraction: Insights from the SUMMIT trial
来自SUMMIT试验的见解:替尔泊肽HFpEF患者心肾终末器官损伤的影响




FS.04 特色科学:备受瞩目的血管治疗结果

北京时间:11月18日 21:00~22:15


Geographical variations of treatment disparities between Black and White patients with peripheral artery disease across the United States

美国各地黑人和白人外周动脉疾病治疗的地域差异


Legend 1 - Anatomically Directed Lower Extremity Gene Therapy for Ulcer Healing: A Double Blind, Randomized, Placebo Controlled Study (Legend 1 Trial)
Legend 1随机、双盲、安慰剂对照试验:用于溃疡愈合的解剖导向下肢基因疗法


Bempedoic Acid and Limb Outcomes in Statin-Intolerant Patients with Peripheral Artery Disease: New insights from the CLEAR OUTCOMES Trial
来自CLEAR OUTCOMES试验的新见解他汀类药物不耐受的外周动脉疾病患者,进行贝派地酸治疗的肢体结局


ONCO PE - Rivaroxaban for 18 Months versus 6 Months in Cancer Patients with Low-risk Pulmonary Embolism: ONCO PE Trial
ONCO PE试验:在肺栓塞风险低危的癌症患者,进行利伐沙班治疗的18个月6个月结果对比




FS.05 特色科学:淀粉样变性、肥厚型心肌病和Danon型心肌病:靶向治疗和特定人群

北京时间:11月18日 22:45~24:00


Danon Disease Phase 1 RP-A501 Results: The First Single-Dose Intravenous Gene Therapy with Recombinant Adeno-Associated Virus (AAV9:LAMP2B) for a Monogenic Cardiomyopathy (Accepted, not confirmed at time of publication)

RP-A501用于Danon病治疗的1期研究结果RP-A501是治疗单基因心肌病的首个单剂量静脉注射基因疗法,其由血清型9重组腺相关病毒(AAV9)衣壳组成,包含一个功能性人源LAMP2B转基因(AAV9.LAMP2B)(已接受,发表时尚未确认)


VALOR-HCM - Mavacamten Treatment in Patients with Obstructive HCM Referred for Septal Reduction Therapy: 128-Week Results from VALOR-HCM Trial
VALOR-HCM试验的128周结果:玛伐凯泰(Mavacamten)在因室间隔缩小术而转诊的阻塞性HCM患者中的疗效


Acoramidis Reduces All-Cause Mortality (ACM) and Cardiovascular-Related Hospitalization (CVH): Initial Outcomes From the ATTRibute-CM Open-Label Extension (OLE) Study
ATTRibute-CM开放标签扩展(OLE)研究的初步结果Acoramidis可降低全因死亡率和心血管相关住院率


Impact of vutrisiran on markers of disease progression in patients with transthyretin amyloidosis with cardiomyopathy in the HELIOS-B trial
来自HELIOS-B试验的结果:vutrisiran对转甲状腺素蛋白淀粉样变性伴心肌病患者疾病进展标志物的影响


SCAN-MP - The prevalence of transthyretin cardiac amyloidosis in older Black and Hispanic individuals with heart failure: The Screening for Cardiac Amyloidosis with Nuclear imaging in Minority Populations Study (SCAN-MP)
SCAN-MP试验(少数民族人群核成像心脏淀粉样变性筛查试验):转甲状腺素心脏淀粉样变性在老年黑人和西班牙裔心衰患者中的患病率


ATTR-Specific Medication in Dual Pathology Aortic Stenosis and Transthyretin Cardiac Amyloidosis
ATTR特异性药物治疗主动脉瓣狭窄和转甲状腺素心脏淀粉样变性双重病理患者中的疗效




FS.06 特色科学:心血管介入治疗结果新见解

北京时间:11月19日 02:30~03:45


Semaglutide Improves Cardiovascular Outcomes in Patients with a History of Coronary Artery Bypass Surgery and Overweight or Obesity: The SELECT Trial

SELECT试验司美格鲁肽可改善既往进行冠脉搭桥手术的超重或肥胖患者的心血管预后


Five-Year Results from the AMPLATZER Amulet Left Atrial Appendage Occluder Randomized Controlled Trial (Amulet IDE)
Amulet IDE随机对照试验5年结局Amplatzer Amulet左心耳封堵器的疗效和安全性


The impact of carbon monoxide to determine the in-hospital prognosis after acute coronary syndrome (ADDICT-ICCU) - (Accepted, not confirmed at time of publication) 
ADDICT-ICCU试验:一氧化碳对急性冠状动脉综合征后院内预后的影响(已接受,发表时尚未确认)


Quantitative Assessment of Mitral Annular Calcification Severity Predicts Outcomes in Severe Aortic Stenosis Patients Undergoing Transcatheter Aortic Valve Replacement
二尖瓣环钙化严重程度的定量评估可预测接受经导管主动脉瓣置换术TAVR的重度主动脉瓣狭窄患者的预后




FS.07 特色科学:现在是制定内分泌调节相关护理标准的时候了

北京时间:11月18日 02:30~03:45


Effect of Tirzepatide on Cardiac Structure and Function in Obese HFpEF: the SUMMIT CMR Substudy

SUMMIT CMR子试验:在合并肥胖HFpEF患者中,探究替尔泊肽心脏结构和功能的影响


Effects of Tirzepatide on the Clinical and Symptom Burden of Patients with Heart Failure and a Preserved Ejection Fraction, Results from the SUMMIT Trial
来自SUMMIT试验结果:射血分数保留型心衰患者中,探究替尔泊肽临床和症状负担的影响


Benefits of Semaglutide on Chronic Kidney Disease Outcomes by Cardiovascular Status or Risk in the FLOW trial
来自FLOW试验的结果:司美格鲁肽对慢性肾脏病结局的益处


相关链接

2024 AHA热点聚焦:8个最新科学研究,3个最新基础科学研究专场,共69项最新研究结果即将揭晓~


医脉通是专业的在线医生平台,“感知世界医学脉搏,助力中国临床决策”是平台的使命。医脉通旗下拥有「临床指南」「用药参考」「医学文献王」「医知源」「e研通」「e脉播」等系列产品,全面满足医学工作者临床决策、获取新知及提升科研效率等方面的需求。

医脉通心血管
快速获取国内外心血管领域重要研究进展和临床指南更新,抢先知晓热门学术会议动态。
 最新文章