银屑病的病理机制丨医学英语视听学习

文摘   2024-07-18 15:00   河南  





语字幕

Psoriasis

银屑病


Psoriasis is a skin disease that causes thick, itchy patches of red skin with silvery scaling. The top two layers of your skin are called the epidermis and dermis. New cells at the bottom of the epidermis constantly move up and replace the older cells above them. 

银屑病是一种导致皮肤变粗、瘙痒、红斑,以及鳞屑的皮肤疾病。皮肤最上面的两层是表皮和真皮。表皮底部的新细胞不断向上移动,替代上面的旧细胞。


Normally, it takes about a month for cells to make this journey. In psoriasis cells reach the skin surface in only six to eight days because of a problem with your immune system. 

正常情况下,细胞需要约 1 个月的时间才能完成这一过程。但是,在银屑病中,由于免疫系统问题,细胞只需要 6-8 天就能到达皮肤表面。


Scientists think your immune system mistakes certain natural substances in your skin as foreign invaders. This causes your immune system to start a counter attack called an inflammatory response

科学家认为,人体免疫系统将皮肤中的某些天然物质误认为外来入侵者,导致免疫系统启动一种称为“炎症反应”的应对反应。


Inflammation is a series of changes that happen in your skin including enlarged blood vessels, growth of more blood vessels, more immune cells in the area forming groups, and faster creation of new skin cells

炎症是皮肤上发生的一系列变化,包括血管扩大更多血管生长病变区域更多免疫细胞聚集,以及新皮肤细胞快速产生


Over time the process of inflammation becomes a cycle. Damaged skin cells signal more immune cells to come to the area. In turn the immune cells cause your skin cells to multiply rapidly and your skin to get thicker. This results in raised itchy inflamed areas called plaques on your skin. 

随着病情不断恶化,炎症过程反复形成。受损的皮肤细胞招募更多免疫细胞聚集到病变区域,而免疫细胞导致皮肤细胞快速增殖,皮肤增厚。这会导致皮肤上形成凸起的瘙痒发炎区域,即斑块


Scientists think that psoriasis is passed down in families through parts of your DNA called genes. You can develop psoriasis if you have these genes then experience certain triggers such as skin injuries, dry skin, infections, stress, smoking, and certain medications. 

科学家认为,银屑病通过 DNA(基因)在家族中遗传。如果具有这些基因,然后接触某些触发因素,如皮肤损伤、皮肤干燥、感染、压力、吸烟和某些药物等,人就会发展为银屑病。


If you have any questions about psoriasis, talk to your healthcare provider.

如果对银屑病存在任何疑问,请咨询医务人员!



相关单词学习


  • Psoriasis


①发音和释义

pso•ri•a•sis/səˈraɪəsɪs/n. 银屑病

A skin disease characterized by scaly patches.


单词 psoriasis 由下列成分构成


psōriân(希腊词干)瘙痒

+

-sis(后缀)状态,病态

(图源:太帅图库)

  • Epidermis


ep•i•der•mis/ˌɛpəˈdɜrmɪs/n. 表皮

The outer, nonvascular, nonsensitive layer of the skin, covering the true skin or corium.


单词 epidermis 由下列成分构成


epi-〈构词成分〉 在…之上

+

dermis 真皮

(图源:太帅图库)

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