Dr. Lu earned his Ph.D. in Immunology from Dartmouth Medical School. He conducted his postdoctoral training with Alexander Rudensky first at the University of Washington and then at Memorial Sloan-Kettering Cancer Center, where he discovered individual miRNAs can influence distinct aspects of Treg cell biology in both healthy and disease states. In 2011, he was recruited to UC San Diego to establish his independent research group.
Dr. Lu’s research mainly focuses on how regulatory T cells in establishing immunological tolerance, and the role of microRNAs in immune regulation. His recent findings have revealed how Treg cells manage specific types of immune response in the intestine, and how miRNAs govern the differentiation and function of effector Treg cells. His long-term goals include developing innovative strategies to manipulate the immune system in the fight against human immunological diseases, as well as educating students and mentoring young scientists.
Hosted by
Dr. Yan Zhang
Time
10:00 am, Monday, October 28, 2024
Venue
Room 1103, Building 5, West Campus
Dr. Zheng earned his Ph.D. in Biological Sciences from Columbia University. He completed his postdoctoral training under Alexander Rudensky at Memorial Sloan-Kettering Cancer Center, where he was the first to map the Foxp3 cistrome in regulatory T cells and identify three intronic conserved non-coding sequences (CNS1 to CNS3) at the Foxp3 genomic locus. In 2009, he established his independent lab at the Salk Institute.
Dr. Zheng’s research centers on the molecular mechanisms governing Treg stability and function, the role of nuclear hormone receptors (NHRs) in T cell differentiation and activity, and the role of Treg cells in supporting stem cell-driven tissue regeneration and repair. His recent work has uncovered the fundamental cellular and molecular processes of Treg differentiation and function, with the goal of identifying new therapeutic targets for autoimmune diseases, metabolic disorders, tissue injuries, and cancer.
Hosted by
Dr. Zhi Liu
(Shanghai Immune Therapy Institute)
Time
10:45 am, Monday, October 28, 2024
Venue
Room 1103, Building 5, West Campus