现因课题组研究需要，拟面向海内外诚聘助理研究员，博士后和生物信息学技术员。
5、将按照医学院以及免疫所有关人事政策，根据申请者情况提供薪酬待遇。
4、提供具有竞争力的待遇，优秀博士后可入选“上海市免疫学研究所博士后创新计划”，年薪24万起。免疫所博士后创新计划实行“3+X” 培养模式，入站3年期满后进行考核，优秀者可继续工作1-2年。
JOIN US
“Myeloid cell biology and metabolism” laboratory directed by Dr. Svetoslav Chakarov in Shanghai Institute of Immunology (SII) at Shanghai Jiao Tong University school of medicine (SJTU-SM) is seeking for a highly motivated candidates for Research Assistant, Postdoc Position, and Bioinformatics Technician.
Obesity, defined as excess fat mass, increases risks for multiple metabolic diseases, such as type 2 diabetes, cardiovascular disease and several types of cancer. The obesity epidemic has intensified efforts to understand the mechanisms controlling obesity-induced tissue remodeling. Adipose tissue associated myeloid cells are hypothesized to play central roles in these diseases through their role as inflammatory mediators. In addition to inflammation, myeloid cells perform ‘extra’ tissue-specific functions termed accessory functions. One such putative accessory function is their metabolic activity. However, the role of myeloid metabolism in shaping tissue remodeling during obesity is poorly understood.
The research projects of the lab utilize cutting-edge interdisciplinary research approaches and aim to understand murine and human innate immune cells/stromal cells interactions during obesity and/or metabolic disease. Multiple novel inducible transgenic and gene targeting murine models, genome sequencing analysis, single-cell RNA-seq, single-cell ATAC-seq, Mass Cytometry (CyTOF), Imaging Mass Cytometry (IMC), Co-detection by indexing (CODEX) will be involved in the ongoing research projects. Recent work from the lab has been published in journals, such as Science, PNAS, Immunity, Journal of Experimental Medicine. The lab is supported by National Natural Science Foundation of China (NSFC) and was selected into talent programs such as the NSFC National for Excellent Young Scientists Fund Program, Shanghai High-level Overseas Talent Introduction Program, Oriental Scholars of Shanghai Universities Distinguished Professor, Foreign Experts Program of Shanghai Science and Technology Commission and participate in the key project of Ministry of Science Technology "Etiology and epidemic prevention technology system research" as a project backbone.
【Research Assistant】
Successful applicants will have a PhD in Immunology, Biology, or Computational Biology. Have published articles as first author in relevant fields, and have postdoctoral research experience in domestic or foreign first-class research institutions. Can carry out scientific research work independently. Expertise in one of the following areas: Immunology (expertise in innate immunity), Computational biology (basic skills), Biology (Rodent handling, Flow cytometry/cell sorting, tissue/cell cultures and imaging).
Candidates will be responsible for designing, developing and implementing experimental protocols, data analysis and interpretation.
【Postdoc Position】
Successful applicants will have a PhD or MD/PhD in Immunology, Biology, or computational biology, under 35 years old and expertise in one of the following areas: Immunology (expertise in innate immunity), Computational biology (basic skills) For experimental Postdoctoral position: Rodent handling, Flow cytometry/cell sorting, tissue/cell cultures and imaging
【Bioinformatics Technician】
Have obtained a master's degree or above in computer, bioinformatics or related majors. Proficient in using relevant computer language. Coding according to experimental requirements. Be interested in immunology/biology/basic medicine.
Specific projects will be discussed with potential applicants depending on their field of expertise and interests. Projects are centered around several main themes:
Macrophage heterogeneity contribution to obesity and metabolic disease.
Eosinophils crosstalk with their environment during metabolic diseases.
Computational centered tools for integration of single-cell RNA-seq, single-cell ATAC-seq, single-cell protein expression and high dimensional spatial imaging.
Please email your curriculum vitae to
svetoslav_chakarov@shsmu.edu.cn.
Please visit our lab website for more details: https://www.shsmu.edu.cn/sii/info/1053/2084.htm
Contact Information
Tel: 021-63846590*776796
email: svetoslav_chakarov@shsmu.edu.cn
If you have any questions, please don't hesitate to contact teacher Xu Jiaqian: 021-63846590-776775
Salary
Provide competitive remuneration.
