昨天发了巨膀胱后，读者纷纷留言：超过多少数值才能够诊断巨膀胱？？那么，巨膀胱究竟有多巨？永远究竟有多远？
1，在孕10到14周，膀胱纵径≥7mm ，可以诊断巨膀胱
2，膀胱纵径＞15mm，是严重的巨膀胱，常常会发展成尿路梗阻
3，如果膀胱纵径在7-15mm，90%胎儿的巨膀胱到孕20周时会自己消失
4，孕11-15周，巨膀胱发病率为0.3%
5，有学者统计了145例早孕期发现的巨膀胱胎儿，结果其中21%有染色体异常。
随访！动态观察极其重要！
严重巨膀胱预后很差，即使通过手术，即使勉强活到新生儿期，仍然有肾衰的危险性！
Fetal megacystis has been reported as early as 10 to 14 weeks’ gestation when the longitudinal bladder diameter is 7 mm or more, The incidence is 0.3% at 11 to 15 weeks.In the largest case series of 145 fetuses with early megacystis, chromosomal abnormalities were detected in 21%.In the chromo- somally normal group, severe megacystis (bladder length >15 mm) was invariably associated with progressive obstructive uropathy.However, if the bladder length was 7 to 15 mm, there was spontaneous resolution of the megacystis by 20 weeks in 90% of cases. Therefore, follow-up ultrasound is necessary to interpret correctly the importance of megacystis detected in the 1st trimester. The role of early vesicocentesis and shunt placement needs further investigation.In fetuses with severe megacystis, survival to the neonatal period was poor even with intervention, and the survivors are at risk of developing renal failure.
