传统的细胞死亡模式如凋亡、坏死等在神经系统疾病中的作用已被广泛研究，但铁死亡作为一种新型的非凋亡性细胞死亡方式，为理解神经退行性疾病的机制提供了新的视角。铁死亡与多种神经系统疾病，如阿尔茨海默病和缺血性脑卒中的发生和发展密切相关。深入探究铁死亡的分子机制，有助于揭示铁死亡在神经系统疾病中的具体作用，从而为针对性干预提供科学依据。为此，选择本刊学者2024年发表的铁死亡的神经保护作用的热点综述文章3篇，推荐读者阅读。
（1）Ferroptosis mechanism and Alzheimer's disease
铁死亡机制与阿尔茨海默病
Lina Feng 1, Jingyi Sun 1, Ling Xia 1, Qiang Shi 1, Yajun Hou 1, Lili Zhang 2, Mingquan Li 3, Cundong Fan 1, Baoliang Sun 1
1 Shandong Key Laboratory of TCM Multi-Target Intervention and Disease Control, the Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong Province, China.
2 Department of Internal Medicine, Taian Traffic Hospital, Taian, Shandong Province, China.
3 Department of Neurology, the Third Affiliated Clinical Hospital of Changchun University of Chinese Medicine, Changchun, Jilin Province, China.
引用本文：
Feng L, Sun J, Xia L, et al. Ferroptosis mechanism and Alzheimer's disease. Neural Regen Res. 2024;19(8):1741-1750.
正文链接：
https://journals.lww.com/nrronline/fulltext/2024/08000/ferroptosis_mechanism_and_alzheimer_s_disease.27.aspx
（2）Ferroptosis: a potential therapeutic target for stroke
铁死亡：脑卒中的潜在治疗靶点
Chengli Liu 1, Guijun Wang 1, Wenrui Han 1, Qi Tian 1, Mingchang Li 1
1 Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China.
引用本文：
Liu C, Wang G, Han W, et al. Ferroptosis: a potential therapeutic target for stroke. Neural Regen Res. 2024;19(5):988-997.
正文链接： https://journals.lww.com/nrronline/fulltext/2024/05000/ferroptosis__a_potential_therapeutic_target_for.26.aspx
（3）Ferroptosis and endoplasmic reticulum stress in ischemic stroke
缺血性脑卒中的铁死亡和内质网应激反应
Yina Li 1, Mingyang Li 2, Shi Feng 2, Qingxue Xu 1, Xu Zhang 2, Xiaoxing Xiong 3, Lijuan Gu 4
1 Central Laboratory; Department of Anesthesiology, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China.
2 Central Laboratory; Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China.
3 Department of Neurosurgery, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China.
4 Central Laboratory, Renmin Hospital of Wuhan University, Wuhan, Hubei Province, China.
引用本文：
Li Y, Li M, Feng S, et al. Ferroptosis and endoplasmic reticulum stress in ischemic stroke. Neural Regen Res. 2024;19(3):611-618.
正文链接：
https://journals.lww.com/nrronline/fulltext/2024/03000/ferroptosis_and_endoplasmic_reticulum_stress_in.36.aspx
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