有靶打靶,践行精准,BRAF 突变 NSCLC 治疗新进展解读

学术   2024-10-13 20:21   浙江  

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✩ 本文仅供医疗卫生等专业人士参考


审批码:TML0032220,有效期为2024-10-11至2025-10-10,资料过期,视同作废


内容审核:方程

项目审核:于轩

题图来源:图虫创意


参考文献:

[1]赵媛媛, 周建英, 范云, 等. BRAF V600 突变型非小细胞肺癌的治疗进展 [J]. 中国癌症杂志, 2021, 31(12): 1145-1152.

[2]Mu YX, Yang K, Hao XZ, et al. Clinical characteristics and treatment outcomes of 65 patients with BRAF-mutated nonsmall cell lung cancer[J]. Front Oncol, 2020, 10: 603.

[3]Couraud S, Barlesi F, Fontaine-Deraluelle C, et al. Clinical outcomes of non-small cell lung cancer patients with BRAF mutations: results from the French Cooperative Thoracic Intergroup biomarkers France study[J]. Eur J Cancer, 2019, 116: 86-97.

[4]Dudnik E, Peled N, Nechushtan H, et al. BRAF Mutant Lung Cancer: Programmed Death Ligand 1 Expression, Tumor Mutational Burden, Microsatellite Instability Status, and Response to Immune Check-Point Inhibitors[J]. J Thorac Oncol. 2018 Aug;13(8):1128-1137.

[5]Guisier F, Dubos-Arvis, Vinas F, et al. Efficacy and safety of anti-PD-1 immunotherapy in patients with advanced NSCLC with BRAF, HER2, or MET mutations or RET translocation: GFPC 01-2018[J]. J Thorac Oncol, 2020, 15(4): 628-636.

[6]Mazieres J, Drilon A, Lusque A, et al.  Immune checkpoint inhibitors for patients with advanced lung cancer and oncogenic driver alterations: results from the IMMUNOTARGET registry[J]. Ann Oncol, 2019, 30(8): 1321-1328.

[7]中国晚期非小细胞肺癌 BRAF 突变诊疗专家共识.

[8]中国医师协会肿瘤多学科诊疗专业委员会,国家肿瘤质控中心肺癌质控专家委员会.   原发性肺癌罕见靶点靶向治疗中国临床诊疗指南(2024 版)[J].   中国肿瘤临床与康复,2024,31(5):265-295.

[9]Planchard D,et al. Dabrafenib plus trametinib in patients with previously untreated BRAFV600E-mutant metastatic non-small-cell lung cancer: an open-label, phase 2 trial  Lancet Oncol. 2017;18(10):1307-1316.

[10]Fan Yun, et al. Safety and Efficacy of Dabrafenib Plus Trametinib in Chinese Patients With BRAF V600E Mutation-Positive Metastatic NSCLC2022 WCLC EP08.02-52

[11]Wiesweg M, et al. Treatment sequences in BRAF-V600-mutant non-small cell lung cancer: First-line targeted therapy versus first-line (chemo-) immunotherapy. 2024 ESMO 1300P.

[12]Russo A, et al. BRAF-mutant metastatic non-small cell lung cancer: Real-world data from the Italian biomarker ATLAS database. 2024 ESMO 1301P.


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