Pineapple, an important tropical herbaceous fruit tree, is renowned for its juicy composite fruits and distinctive aroma. Its extensive evolutionary history, primarily driven by vegetative propagation, has led to a highly heterozygous genome that has been difficult to fully resolve. Here, Feng et al. (pages 2208–2225) have successfully assembled the first telomere-to-telomere genome of pineapple, accompanied by a meticulously curated, highquality gene structure annotation. These comprehensive genomic resources provide a complete map for postgenomic research and breeding efforts in pineapple. The cover image features a flowering hybrid F1 plant, the result of a cross between BL and LY, two pineapple varieties used in the study.
JIPB:中国农科院发现通过ROS抗穗枯病的机制
穗枯病Fusarium head blight (FHB)是影响小麦生长发育的一种重要病害。本研究发现了一个该病菌的效应子蛋白FgEC1在侵袭小麦时被诱导, 是导致小麦感病的一个关键基因。
FgEC1抑制了 flg22- and chitin诱导的胼胝质和ROS的产生。 FgEC1 直接与TaGF14b互作, 该基因在小麦被侵袭时在穗部被诱导。过表达TaGF14b可以在不导致产量下降的情况下来提高小麦对穗枯病的抗性。
TaGF14b 与NADPH oxidase respiratory burst oxidase homolog D (TaRBOHD)，从而防止其被26S proteasome降解. FgEC1通过抑制TaGF14b 与TaRBOHD的互作从而促进了TaRBOHD降解 ，导致活性氧水平显著下降，进而使得小麦感病。
Model for the virulence mechanism of FgEC1 in suppressing wheat immunity. Generally, upon pathogen infection, TaGF14b binds to TaRBOHD to reduce its degradation by the 26S proteasome system, resulting in increased ROS production that restricts pathogen colonization and induces plant cell immune responses. However, during initial infection, Fusarium graminearum delivers FgEC1 into wheat cells. FgEC1 competes with the intracellular fragment of TaRBOHD to bind to TaGF14b, which indirectly promotes TaRBOHD degradation. As a result, FgEC1 reduces TaRBOHD-mediated ROS generation during F. graminearum infection.
原文：Fusarium graminearum effector FgEC1 targets wheat TaGF14b protein to suppress TaRBOHD-mediated ROS production and promote infection
