Nüwa is a mother godness in Chinese culture who molded humans with yellow clay. The clay models show the 46 chromosomes in each cell of human body. A complete genome of a male Han Chinese with all 46 chromosomes assembled at telomere-to-telomere level is presented. See page 745–761 by Chentao Yang et al. for details. The image is credited to Cheng Guo and Huifang Xiao.
PBJ:东北林业大学揭示一个响应盐胁迫的信号通路
Glycine-rich RNA-binding proteins (GRPs)被认为参与了植物对环境胁迫的响应过程。本研究发现了一个受盐胁迫诱导的BpGRP1 (glycine-rich RNA-binding protein)参与了植物对盐胁迫的应答。
BpGRF3 (growth-regulating factor 3) 作用于BpGRP1上游发挥作用. 过表达BpGRF3 显著提高了植物对盐胁迫的耐受性，而突变体 grf3-1的表型恰好相反。
BpGRF3在蛋白水平上与BpSHMT互作共同调控BpGRP1. 而BpmiR396c则作用于BpGRF3上有负调控植物对盐胁迫的耐受性。
小结：本研究揭示了一个调控植物盐胁迫耐受性的信号通路BpmiR396c/BpGRF3-BpGRP1。
A putative model for the mediation of the transcriptional regulation of BpGRP1 by the BpmiR396c-BpGRF3 module. This model may provide a new perspective for understanding the mechanism of birch salt tolerance. Under salt stress, a decrease in BpmiR396c diminishes cleavage of the downstream BpGRF3 transcripts, and the encoded protein activates transcription of the downstream gene BpGRP1. With the interaction between BpGRF3 and BpSHMT, BpGRP1 is activated to regulate the associated physiological pathways, which increases the ROS scavenging ability, reduces the degree of damage to the plasma membrane and ultimately enhances the salt stress response in birch.
原文：BpGRP1 acts downstream of BpmiR396c/BpGRF3 to confer salt tolerance in Betula platyphylla
