On the cover: An ancient ash tree growing in Herefordshire, England. In this issue, Hill et al. (pages R315–R316) estimate that the total cost of the invasive tree disease ash dieback in Britain will be £15 billion. The true cost of tree diseases has not previously been fully appreciated. There is a clear economic imperative to prevent future arrival of plant pests and diseases, and to effectively mitigate against those that do arrive. Trade in live plants and other biological material represents a market failure with severe social and ecological consequences. Photo © Gabriel Hemery. www.gabrielhemery.com.
JIPB:河南大学揭示维持拟南芥生长素平衡的新机制
Anchorene是一种内院的来自类胡萝卜素的dialdehyde and diapocarotenoid物质, 它通过调控生长素平衡来影响根系发育。
anchorene可以诱导多种生长素的效应，这种效应依赖于indole-3-pyruvate介导的生长素合成路径以及由Group II Gretchen Hagen 3 (GH3) 介导的生长素失活路径（conjugation of indole-3-acetic acid (IAA) to amino acids, leading to the formation of inactivated storage forms）.
anchorene处理会提高生长素水平，降低失活形式的IAA–amino acid conjugates 和 oxIAA.转录组的分析显示anchorene 诱导相当数量响应生长素的基因，而且这个过程依赖对Group II GH3s的抑制效应. 分析显示anchorene抑制GH3.17介导的IAA conjugation with glutamate.
小结：本研究揭示了 anchorene通过维持生长素平衡调控植物生长发育的机制。
原文：Anchorene, a carotenoid-derived growth regulator, modulates auxin homeostasis by suppressing GH3-mediated auxin conjugation
