Alleviating suffering helps the completion of medical procedures and is the perpetual pursuit of medical professions. As early as in Han dynasty, Hua Tuo made the herbal anesthetic potion “Mafeisan” for surgery. The contemporary mannose extracted from cranberry mitigates the side effects to complement chemotherapeutic procedures. See page 904–922 by Yuan-li Ai et al. for details.
PLANT CELL:中科院揭示调控拟南芥盐胁迫耐受性的新机制
光呼吸是一个耗能代谢过程。本研究发现FERONIA (FER)调控盐胁迫条件下拟南芥对盐胁迫的响应过程，这依赖于该激酶对光呼吸的调控。FER mutation会导致植物对盐胁迫的超敏感表型，但是抑制一个参与光呼吸路径中的酶ferredoxin-dependent glutamate synthase 1 (GLU1)（an enzyme that participates in the photorespiratory pathway by producing glutamate）, 会显著改善垓激酶突变体 fer-4对盐胁迫的超敏感表型，这与glycine水平的下降有关。
相反破坏serine hydroxymethyltransferase1 (SHM1)（ increase glycine levels by hampering the conversion of glycine to serine in the photorespiratory cycle）, 则会导致FER激酶突变体fer-4 对盐胁迫的敏感度增高。
分析显示，FER 与SHM1互作并将其磷酸化导致它的稳定性显著增高.
此外，作者还发现proline 及其中间产物 △1-pyrroline-5-carboxylate (P5C)也是fer-4导致该突变体对盐胁迫超敏感的原因。
小结：本研究揭示了FERONIA (FER)激酶影响拟南芥盐胁迫耐受性的机制。
原文：FERONIA regulates salt tolerance in Arabidopsis by controlling photorespiratory flux
