近日,沈阳药科大学项珂博士入职福建中医药大学药学院,以讲师身份加入结构药理学与中药化学生物学研究所。
项珂博士,福建中医药大学药学院讲师。研究方向为中药及天然药物中活性先导化合物的发现,以第一/共一作者在Ultrasonics Sonochemistry、Food Chemistry、Bioorganic Chemistry、Bioorganic & Medicinal Chemistry等期刊发表SCI论文4篇;申请专利6项,已授权专利4项。
研究方向
1.活性天然产物的精准导向分离
2.闽台特色药用植物资源的深度开发与利用
2019.06-2024.06 沈阳药科大学,天然药物化学,理学博士
2017.09-2019.06 沈阳药科大学,化学工艺专业(硕博连读)
2013.09-2017.06 蚌埠医科大学,制药工程,工学学士
2. Ke Xiang, Yan Liu, Rui Zhu, Yang Xu, Dejuan Sun, Yueying Yang, Yushu Yan, Bingyou Yang, Hua Li, Lixia Chen, Cytotoxic withanolides from the stems and leaves of Physalis ixocarpa. Food Chemistry, 2023, 439: 138136. (IF=8.4)
3. Ke Xiang, Chen Li, Mingxue Li, Zhuo-Rui Song, Xiaoxin Ma, Dejuan Sun, Hua Li, Lixia Chen.Withanolides isolated from Tubocapsicum anomalum and their antiprolifera-tive activity. Bioorganic Chemistry, 2021, 110(4):104809. (IF=5.1)
4. Yueying Yang1, Ke Xiang1, Dejuan Sun, Mengzhu Zheng, Zhuorui Song, Mingxue Li, Xuanbin Wang, Hua Li, Lixia Chen. Withanolides from dietary tomatillo suppress HT1-080 cancer cell growth by targeting mutant IDH1. Bioorganic & Medicinal Chemistry, 2021, 36(4):116095. (IF=3.3)
5. Yanmei Chen, Jiahui Zhang, Yueying Yang, Ke Xiang, Hua Li, Dejuan Sun, Lixia Chen. Kynurenine-3-monooxygenase (KMO): From its biological functions to therapeutic effect in diseases progression. Journal of Cellular Physiology, 2022, 237(12): 4339-4355. (IF=5.6)
用靶点蛋白质的火把照亮化合物的天空,在黑夜中寻找治愈人间的药物分子