向您推荐Science China Life Sciences 2024年10月8~10月12日在线文章,敬请关注!
01
RESEARCH PAPER
Individual and joint exposures to PM2.5 constituents and mortality risk among the oldest-old in China (中国超高龄人群暴露于PM2.5成分与死亡风险的关系)
Yaqi Wang, Yang Yuan, Shaocai Mo, Fang Wang, Jing Wei, Yao Yao, Yi Zeng (曾毅)*, Yunquan Zhang (张云权)*
doi: 10.1007/s11427-024-2718-9
02
RESEARCH PAPER
RGS22 maintains the physiological function of ependymal cells to prevent hydrocephalus (RGS22在先天性脑积水发病中的作用机制)
Xue Pang, Lin Gu, Qiu-Ying Han, …, Hong Cai (蔡宏)*, Tao Li (李涛)*
doi: 10.1007/s11427-024-2720-8
03
RESEARCH PAPER
Compound heterozygous mutation of AFG3L2 causes autosomal recessive spinocerebellar ataxia through mitochondrial impairment and MICU1 mediated Ca2+ overload (AFG3L2通过线粒体功能障碍和MICU1介导的Ca²⁺超载导致常染色体隐性脊髓小脑性共济失调)
Hongyu Li, Qingwen Ma, Yan Xue, …, Fanyi Zeng (曾凡一)*
doi: 10.1007/s11427-023-2549-2
04
RESEARCH PAPER
Human iPSC-derived mesenchymal stem cells relieve high blood pressure in spontaneously hypertensive rats via splenic nerve activated choline acetyltransferase-positive cells (人诱导多能干细胞(iPSC)衍生的间充质干细胞缓解自发性高血压大鼠的高血压的作用机制)
Zhen Zhang, Weijun Huang, Xiaoran Zhang,..., Andy Peng Xiang (项鹏)*, Qiuling Xiang (向秋玲)*
doi: 10.1007/s11427-023-2675-2
05
RESEARCH PAPER
Genome-wide CRISPR screens identify CLC-2 as a drug target for anti-herpesvirus therapy: tackling herpesvirus drug resistance (CLC-2是一种抗疱疹病毒治疗靶点)
Fayu Yang, Nan Wei, Shuo Cai,..., Guangzhi Tong(童光志)*, Feng Gu (谷峰)*
doi: 10.1007/s11427-023-2627-8
06
RESEARCH PAPER
Graph based recurrent network for context specific synthetic lethality prediction (用于特定生物背景下合成致死基因对预测的图循环神经网络算法)
Yuyang Jiang, Jing Wang, Yixin Zhang,..., Jinsong Su (苏劲松)*, Song He (何松)*, Xiaochen Bo (伯晓晨)*
doi: 10.1007/s11427-023-2618-y
07
RESEARCH PAPER
Integrating spatial transcriptomics and single-nucleus RNA-seq revealed the specific inhibitory effects of TGF-β on intramuscular fat deposition (TGF-β对肌内脂肪沉积的特异性抑制作用机制)
Xiaoyu Wang, Chuchu Chen, Chenggan Li,..., Delin Mo (莫德林)*
doi: 10.1007/s11427-024-2696-5
08
INSIGHT
Timing of biomarker changes preceding Alzheimer’s disease: for diagnosis, treatment or prevention? (阿尔茨海默病前生物标志物变化:用于诊断、治疗或预防)
Meina Quan (全美娜)*
doi: 10.1007/s11427-024-2733-7