Sci China Life Sci 2024年第9期文章概览

学术   2024-09-13 14:22   北京  

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COVER ARTICLE

Inhibition mechanisms of CRISPR-Cas9 by AcrIIA25.1 and AcrIIA32

Jianlin Zheng, Yuwei Zhu, Tengjin Huang, Wenbo Gao, Jiale He, Zhiwei Huang

SCIENCE CHINA Life Sciences, 2024, 67(9): 1781-1791

REVIEW

Biomolecular condensates and disease pathogenesis

Ke Ruan, Ge Bai, Yanshan Fang, Dan Li, Tingting Li, Xingguo Liu, Boxun Lu, Qing Lu, Zhou Songyang, Shuguo Sun, Zheng Wang, Xin Zhang, Wen Zhou, Hong Zhang

SCIENCE CHINA Life Sciences, 202467(9)1792-1832


Permafrost carbon cycle and its dynamics on the Tibetan Plateau

Leiyi Chen, Guibiao Yang, Yuxuan Bai, Jinfeng Chang, Shuqi Qin, Futing Liu, Mei He, Yutong Song, Fan Zhang, Josep Peñuelas, Biao Zhu, Guoying Zhou, Yuanhe Yang

SCIENCE CHINA Life Sciences, 202467(9) 1833-1848


RESEARCH PAPER

Ononin inhibits triple-negative breast cancer lung metastasis by targeting the EGFR-mediated PI3K/Akt/mTOR pathway

Kumar Ganesan, Cong Xu, Jianming Wu, Bing Du, Qingqing Liu, Yue Sui, Cailu Song, Jinhui Zhang, Hailin Tang, Jianping Chen

SCIENCE CHINA Life Sciences, 202467(9)1849-1866


The p38/MAPK pathway as a therapeutic target to prevent therapeutic escape of breast cancer stem cells

Weixiao Yan, Xiaotong Wang, Wenjing Wang, Qi Guo, Na Huang, Hao Chen, Xing-Jie Liang, Yu Han, Dandan Liu, Jinchao Zhang

SCIENCE CHINA Life Sciences, 202467(9)1867-1880


CircZFR promotes colorectal cancer progression via stabilizing BCLAF1 and regulating the miR-3127-5p/RTKN2 axis

Jiaxin Chen, Huijuan Wang, Jianbin Xu, Engeng Chen, Qing Meng, Jiawei Wang, Haoyi Xiang, Wei Zhou, Ge Shan, Zhenyu Ju, Zhangfa Song

SCIENCE CHINA Life Sciences, 202467(9)1881-1898


TBC1D1 is an energy-responsive polarization regulator of macrophages via governing ROS production in obesity

Qi Wang, Ping Rong, Wen Zhang, Xinyu Yang, Liang Chen, Ye Cao, Minjun Liu, Weikuan Feng, Qian Ouyang, Qiaoli Chen, Hailong Li, Hui Liang, Fanguo Meng, Hong-Yu Wang, Shuai Chen

SCIENCE CHINA Life Sciences, 202467(9) 1899-1914


Deamidation enables pathogenicSMAD6 variants to activate the BMP signaling pathway

Ling Li, Lei Lu, Ziqi Xiao, Jingyi Lv, Hefeng Huang, Bo Wu, Tongjin Zhao, Chengtao Li, Weimin Wang, Hongyan Wang

SCIENCE CHINA Life Sciences, 202467(9)1915-1927


Early-onset and later-onset cancer: trends, risk factors, and prevention in Northern China

Tong Liu, Chen-An Liu, Qing-Song Zhang, Qi Zhang, Yi-Ming Wang, Meng-Meng Song, Shi-Qi Lin, Li Deng, Shou-Ling Wu, Han-Ping Shi

SCIENCE CHINA Life Sciences, 202467(9) 1928-1940


Identification ofLRRC46 as a novel candidate gene for high myopia

Lingxi Jiang, Chao Dai, Yao Wei, Bo Zhao, Qi Li, Zhengzheng Wu, Liang Zou, Zimeng Ye, Zhenglin Yang, Lulin Huang, Yi Shi

SCIENCE CHINA Life Sciences, 202467(9) 1941-1956


TIP60 acetylation of Bub1 regulates centromeric H2AT120 phosphorylation for faithful chromosome segregation

Mengjie Sun, Biying Yang, Guangwei Xin, Yao Wang, Jia Luo, Qing Jiang, Chuanmao Zhang

SCIENCE CHINA Life Sciences, 202467(9)1957-1969


LPS-related muscle loss is associated with the alteration of Bacteroidetes abundance, systemic inflammation, and mitochondrial morphology in a weaned piglet model

Jiayi Yu, Changbing Zheng, Qiuping Guo, Yulong Yin, Yehui Duan, Fengna Li

SCIENCE CHINA Life Sciences, 202467(9)1970-1988


Unveiling the distinctive traits of functional rye centromeres: minisatellites, retrotransposons, and R-loop formation

Chang Liu, Shulan Fu, Congyang Yi, Yang Liu, Yuhong Huang, Xianrui Guo, Kaibiao Zhang, Qian Liu, James A. Birchler, Fangpu Han

SCIENCE CHINA Life Sciences, 202467(9)1989-2002


Genomic insights into adaptation to bipedal saltation and desert-like habitats of jerboas

Simin Chai, Yujie Chong, Daiqing Yin, Qiang Qiu, Shixia Xu, Guang Yang

SCIENCE CHINA Life Sciences, 202467(9)2003-2015


Global convergence in terrestrial gross primary production response to atmospheric vapor pressure deficit

Chao Huang, Jingfeng Huang, Jingfeng Xiao, Xing Li, Hong S. He, Yu Liang, Fusheng Chen, Hanqin Tian

SCIENCE CHINA Life Sciences, 202467(9)2016-2025


INSIGHT

Decoding aging: examining the non-evolutionary event from an evolutionary perspective

Yannan Guo, Kang Xu, Jianping Cai, Zhao Wang

SCIENCE CHINA Life Sciences, 202467(9)2026-2029


Central cell: the key to determine persistent pollen tube attraction or termination

Jiang-Guo Meng, Shi-Zhen Li, Hong-Ju Li

SCIENCE CHINA Life Sciences, 202467(9) 2030-2032


LETTER TO THE EDITOR

PRC2 primes bivalent genes for transcription induction independent of histone methyltransferase activity

Meihan Gong, Ye Yuan, Zhongye Dai, Xuejiao Lv, Jiacheng Su, Dawei Huo, Lin Niu, Xu Chen, Xudong Wu

SCIENCE CHINA Life Sciences, 202467(9)2033-2035


Variant PRC1 subunit RYBP/YAF2 forms condensate with RING1B and promotes H2AK119ub deposition

Yanjiang Liu, Gongcheng Hu, Shengxiong Yang, Chenghong Yan, Juehan Wang, Guangjin Pan, Hongjie Yao

SCIENCE CHINA Life Sciences, 202467(9)2036-2038


Mutations in wheatTaAPA2 gene result in pleiotropic effects on plant architecture

Shengsheng Bai, Guiping Wang, Rui Song, Yanna Liu, Lei Hua, Jinwei Yang, Lijun Zhang, Shams ur Rehman, Xiaohua Hao, Lifeng Hou, Chaozhong Zhang, Hongna Li, Yanyan Liang, Lihua Zhao, Yan Xue, Zheng Wang, Shisheng Chen

SCIENCE CHINA Life Sciences, 202467(9)2039-2042


RESEARCH HIGHLIGHT

Illuminating functions of evolutionarily conserved longnon-coding RNAs

Ruiqiao He, Fangqing Zhao

SCIENCE CHINA Life Sciences, 202467(9)2043-2044


Enhancing whole yeast genome rearrangements throughmultiple LoxPsym sequences

Bing-Zhi Li, Ying-Jin Yuan

SCIENCE CHINA Life Sciences, 202467(9)2045-2047


Erythrocytes serve as a template to create nanozymes with uniform Fe single-atom sites for healing bacteria-infected wound

Thinh Viet Dang, Moon Il Kim

SCIENCE CHINA Life Sciences, 202467(9)2048-2050

中国科学生命科学
《中国科学:生命科学》报道生物学、 医学和农学及生态学领域的基础研究与应用研究方面具有重要意义和创新性的最新研究成果。
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