6月25日上午8点30分（北京时间），日本蛋白质组学协会(JPrOS)将召开第三届自上而下蛋白组学线上研讨会。届时将有3位领域内的专家介绍自上而下蛋白组学样品处理和仪器方法的最新研究进展。此次会议由爱媛大学的武森信晓主持，更多细节和线上注册链接请点击
https://www.jproswebinar.com/
会议日程（北京时间）
8:30 – 8:40 Opening Remarks (Nobuaki Takemori)
8:40 – 9:20 Influence of Different Sample Preparation Approaches on Proteoform Identification by Top-Down Proteomics
Dr. Philipp T. Kaulich - Christian-Albrechts-Universität Kiel (Germany)
In addition to mass spectrometry techniques, the choice of an appropriate sample preparation method is critical for top-down proteomics. But there are a variety of sample preparation methods for intact proteoforms. Which one should you use? Dr. Kaulich gave a very clear answer to this difficult question at this year’s ASMS conference in Anaheim just a few weeks ago. Join us for this webinar to learn about the best sample preparation methods available today!
9:20 – 10:00 Enhanced Sequencing of Intact Proteins and Their Subunits using Ion-Ion and Ion-Photon Reactions in the Gas-Phase
Dr. Luca Fornelli – University of Oklahoma (USA)
"I'm interested in top-down proteomics, but I’ll need special mass spectrometry equipment, right?" This is a question we often get from JPrOS members. Dr. Fornelli is a true expert who has successfully analyzed many intact proteoforms using bench-top Orbitrap mass spectrometers which many of you already have access to. In his talk, you will get insights into new proteoform analysis techniques using state-of-the-art mass spectrometry, as well as practical advice on how to start top-down proteomics studies in your own laboratory.
10:00 – 10:40 Electron Activated Dissociation for Protein Characterization
Dr. Takashi Baba – Sciex (Canada)
To accurately identify intact proteoforms by mass spectrometry, it is important not only to obtain high-resolution MS information from large protein molecules, but also to dissociate their ions into fragments for determining their post-translational modifications and sequences. Dr. Baba will give a highly informative lecture covering everything from the principles of proteoform identification by mass spectrometry to the latest dissociation methods for top-down proteomics.
