Research Articles
1. Programming tumor evolution with selection gene drives to proactively combat drug resistance
2. Complete substitution with modified nucleotides in self-amplifying RNA suppresses the interferon response and increases potency
3. Precise in vivo RNA base editing with a wobble-enhanced circular CLUSTER guide RNA (Highlight by Research Briefing)
Research Briefing: G•U wobble base pairs improve site-directed RNA base editing
4. Template-independent enzymatic synthesis of RNA oligonucleotides （Highlight by News&Views)
News&Views: Enzymatic synthesis of RNA oligonucleotides
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