Research Articles
An engineered Cas12a enables higher-order combinatorial functional genomic screens using CRISPR interference.
原文链接 https://www.nature.com/articles/s41587-024-02224-0
News&Views: Decoding gene regulation with CRISPR perturbations
原文链接 https://www.nature.com/articles/s41587-024-02222-2
CRISPRai simultaneously activates and represses two genes in single cells.
原文链接 https://www.nature.com/articles/s41587-024-02213-3
News&Views: Decoding gene regulation with CRISPR perturbations
原文链接 https://www.nature.com/articles/s41587-024-02222-2
Programmable and reversible CRISPRi-based genetic circuits function in a variety of plants.
原文链接 https://www.nature.com/articles/s41587-024-02236-w
Research Briefing: Advancing programmable gene expression in plants using CRISPRi-based Boolean gates
原文链接 https://www.nature.com/articles/s41587-024-02273-5
Multiplexed orthogonal base editing systems introduce different point mutations at two loci simultaneously.
原文链接 https://www.nature.com/articles/s41587-024-02240-0
The landscape of RNA isoforms in human cortex is revealed by deep long-read RNA sequencing.
原文链接 https://www.nature.com/articles/s41587-024-02235-x
A confocal microscopy technique enables high-resolution intravital imaging over multiple hours.
原文链接 https://www.nature.com/articles/s41587-024-02249-5
Prime editing in hematopoietic cells is improved by engineering nucleotide metabolism.
原文链接 https://www.nature.com/articles/s41587-024-02266-4
Cas9 shows trans-cleavage activity and can be used for DNA and RNA detection.
原文链接 https://www.nature.com/articles/s41587-024-02255-7
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