[1] Revolution Medicines Provides Clinical Updates from its RAS(ON) Inhibitor Portfolio. Retrieved December 2, 2024 from https://www.globenewswire.com/news-release/2024/12/02/2989693/0/en/Revolution-Medicines-Provides-Clinical-Updates-from-its-RAS-ON-Inhibitor-Portfolio.html

[2] Clinical Updates on RAS(ON) Inhibitors: Monotherapy & Combinations. Retrieved December 2, 2024 from https://ir.revmed.com/static-files/34f3d4bd-7563-44a8-8eab-ea087b56919f

[3] Janux Announces Doses Selected for Phase 1b Expansion Trials Supported by Encouraging Efficacy and Safety Profile Observed in Phase 1a Dose Escalation for JANX007 in mCRPC. Retrieved December 3, 2024, from https://investors.januxrx.com/investor-media/news/news-details/2024/Janux-Announces-Doses-Selected-for-Phase-1b-Expansion-Trials-Supported-by-Encouraging-Efficacy-and-Safety-Profile-Observed-in-Phase-1a-Dose-Escalation-for-JANX007-in-mCRPC/default.aspx

[4] Delta-Fly Pharma Inc.: Update for Development Status of DFP-17729. Retrieved December 3, 2024, from https://www.businesswire.com/news/home/20241204497142/en/Delta-Fly-Pharma-Inc.-Update-for-Development-Status-of-DFP-17729

[5] Sirius Therapeutics to Present Data from Its Phase 1 Clinical Trial of Factor XI siRNA, a Long-Acting Next-Generation Anticoagulant for Thromboembolic Disorders at the 66th ASH Annual Meeting and Exposition. Retrieved December 3, 2024, from https://www.businesswire.com/news/home/20241202142345/en/Sirius-Therapeutics-to-Present-Data-from-Its-Phase-1-Clinical-Trial-of-Factor-XI-siRNA-a-Long-Acting-Next-Generation-Anticoagulant-for-Thromboembolic-Disorders-at-the-66th-ASH-Annual-Meeting-and-Exposition

[6] MBX Biosciences Announces MBX 2109 Phase 1 Study Results Published in The Journal of Clinical Endocrinology and Metabolism. Retrieved December 3, 2024, from https://www.globenewswire.com/news-release/2024/12/02/2989746/0/en/MBX-Biosciences-Announces-MBX-2109-Phase-1-Study-Results-Published-in-The-Journal-of-Clinical-Endocrinology-and-Metabolism.html

[7] The majority of the human genome is transcribed into RNAs that do not encode for the production of proteins. These non-coding RNAs (ncRNAs) play crucial biological roles in regulating cellular processes, making them an attractive therapeutic target for drug development for a range of diseases. Retrieved December 3, 2024, from https://www.resalistherapeutics.com/science/noncoding-rna-ncrna/

[8] Resalis Therapeutics Announces Initiation of Phase 1 Clinical Trial for RES-010 in Obesity. Retrieved December 6, 2024, from https://www.businesswire.com/news/home/20241203530139/en/Resalis-Therapeutics-Announces-Initiation-of-Phase-1-Clinical-Trial-for-RES-010-in-Obesity

[9] QurAlis Doses First Patient With ALS in Phase 1 Clinical Trial Evaluating QRL-101, a First-in-Class Kv7 Precision Therapy for ALS. Retrieved December 6, 2024, from https://www.prnewswire.com/news-releases/quralis-doses-first-patient-with-als-in-phase-1-clinical-trial-evaluating-qrl-101-a-first-in-class-kv7-precision-therapy-for-als-302321243.html

[10] Senti Bio Announces Positive Initial Clinical Data in Phase 1 Clinical Trial of SENTI-202, a Logic Gated, Selective CD33/FLT3-Targeting CAR-NK Cell Therapy for the Treatment of Relapsed/Refractory Hematologic Malignancies Including AML. Retrieved December 2, 2024, from https://www.globenewswire.com/news-release/2024/12/02/2989665/0/en/Senti-Bio-Announces-Positive-Initial-Clinical-Data-in-Phase-1-Clinical-Trial-of-SENTI-202-a-Logic-Gated-Selective-CD33-FLT3-Targeting-CAR-NK-Cell-Therapy-for-the-Treatment-of-Relap.html

[11] Sudo Biosciences Announces First Participants Dosed in Phase 1 Trial of Brain-Penetrant Allosteric TYK2 Inhibitor SUDO-550. Retrieved December 6, 2024, from https://www.businesswire.com/news/home/20241202300740/en/Sudo-Biosciences-Announces-First-Participants-Dosed-in-Phase-1-Trial-of-Brain-Penetrant-Allosteric-TYK2-Inhibitor-SUDO-550/

[12] Recursion announces first patient dosed in Phase 1/2 clinical study of REC-1245, a potential first-in-class, RBM39 degrader for Biomarker-Enriched Solid Tumors and Lymphoma. Retrieved December 6, 2024, from https://ir.recursion.com/news-releases/news-release-details/recursion-announces-first-patient-dosed-phase-12-clinical-study

[13] Spyre Therapeutics Announces First Participants Dosed in Phase 1 Trials of Novel Half-life Extended Anti-TL1A Antibodies. Retrieved December 6, 2024, from https://www.prnewswire.com/news-releases/spyre-therapeutics-announces-first-participants-dosed-in-phase-1-trials-of-novel-half-life-extended-anti-tl1a-antibodies-302319340.html

[14] Adcentrx Therapeutics Doses First Patient in Phase 1b Expansion Cohorts with ADRX-0706 Nectin-4 ADC. Retrieved December 6, 2024, from https://www.prnewswire.com/news-releases/adcentrx-therapeutics-doses-first-patient-in-phase-1b-expansion-cohorts-with-adrx-0706-nectin-4-adc-302319257.html

[15] Epsilogen Announces Initiation of Phase Ib Trial of MOv18 IgE. Retrieved December 6, 2024, from https://www.businesswire.com/news/home/20241202478799/en/Epsilogen-Announces-Initiation-of-Phase-Ib-Trial-of-MOv18-IgE/

[16] Jasper Therapeutics Announces First Patient Dosed in Phase 1b/2a ETESIAN Clinical Study of Briquilimab in Asthma. Retrieved December 6, 2024, from https://www.globenewswire.com/news-release/2024/12/02/2990163/0/en/Jasper-Therapeutics-Announces-First-Patient-Dosed-in-Phase-1b-2a-ETESIAN-Clinical-Study-of-Briquilimab-in-Asthma.html

[17] OncoC4 Announces FDA Clearance of IND Application for Potential Best-in-Class PD-1/VEGF Bispecific AI-081 in Advanced Solid Tumors. Retrieved December 6, 2024, from https://www.globenewswire.com/news-release/2024/12/02/2989768/0/en/OncoC4-Announces-FDA-Clearance-of-IND-Application-for-Potential-Best-in-Class-PD-1-VEGF-Bispecific-AI-081-in-Advanced-Solid-Tumors.html

[18] MAPLIGHT THERAPEUTICS ANNOUNCES RESULTS FROM PHASE 1 TRIAL OF NOVEL M1/M4 MUSCARINIC AGONIST IN DEVELOPMENT FOR TREATMENT OF SCHIZOPHRENIA AND ALZHEIMER'S DISEASE PSYCHOSIS. Retrieved December 6, 2024, from https://www.prnewswire.com/news-releases/maplight-therapeutics-announces-results-from-phase-1-trial-of-novel-m1m4-muscarinic-agonist-in-development-for-treatment-of-schizophrenia-and-alzheimers-disease-psychosis-302317925.html

[19] Palisade Bio Announces Preliminary Data from Phase 1 Clinical Study of PALI-2108 for the Treatment of Moderate-to-Severe Ulcerative Colitis Appears to be Safe and Well Tolerated in Treated Subjects. Retrieved December 6, 2024, from https://www.globenewswire.com/news-release/2024/12/03/2990602/0/en/Palisade-Bio-Announces-Preliminary-Data-from-Phase-1-Clinical-Study-of-PALI-2108-for-the-Treatment-of-Moderate-to-Severe-Ulcerative-Colitis-Appears-to-be-Safe-and-Well-Tolerated-in.html

[20] Delix Therapeutics Announces Dosing of First Patient in Phase 1b Clinical Trial for DLX-001 in Major Depressive Disorder. Retrieved December 6, 2024, from https://www.delixtherapeutics.com/news/delix-therapeutics-announces-dosing-of-first-patie/

[21] Nkarta Announces IND Clearance of Investigator-Sponsored Trial in Myasthenia Gravis and Opening of Enrollment for Ntrust-2. Retrieved December 6, 2024, from https://www.globenewswire.com/news-release/2024/12/05/2992165/0/en/Nkarta-Announces-IND-Clearance-of-Investigator-Sponsored-Trial-in-Myasthenia-Gravis-and-Opening-of-Enrollment-for-Ntrust-2.html