Anti-Jo1 autoantibodies, from clinic to the bench (Review)
Angeles S. Galindo-Feria, Begum Horuluoglu, Ingrid E. Lundberg
这篇特约综述讨论了与抗Jo-1自身抗体相关的临床表现以及与临床特征的关系。此外，作者还回顾了抗体的分子特征以及它们如何影响免疫系统的细胞，以便了解可能的疾病机制。
How to cite: Galindo-Feria AS, Horuluoglu B, Lundberg IE. Anti-Jo1 autoantibodies, from clinic to the bench. Rheumatol Autoimmun 2022; 2: 57-68. doi: 10.1002/rai2.12035
（扫码阅读全文）
Phenotypical statin-associated immune-mediated necrotizing myositis with histological features of inclusion body myositis (Case Report)
本文报告了一例与他汀类药物相关的免疫介导的坏死性肌病和包涵体肌炎。
（扫码阅读全文）
High-throughput transcriptomic profiling of mRNAs and lncRNAs in the dermatomyositis muscle by RNA sequencing (Original Article)
Ke Li, Yubao Ma, Shanchun Zhang, Rui Ban, Qiang Shi
本研究评估了皮肌炎患者、其他特发性炎性肌病患者和健康对照的肌肉组织中差异表达的mRNA和长链非编码RNA (lncRNA)的转录组谱，发现上调的mRNA参与了固有免疫反应和I型干扰素信号通路，可能在皮肌炎的发病机制中发挥重要作用。
How to cite: Li, K, Ma, Y, Zhang, S, Ban, R, Shi, Q. High-throughput transcriptomic profiling of mRNAs and lncRNAs in the dermatomyositis muscle by RNA sequencing. Rheumatol Autoimmun 2023; 3: 166-178. doi: 10.1002/rai2.12078
（扫码阅读全文）
Successful treatment of rapidly progressive interstitial lung disease complicated by a refractory pneumomediastinum in a patient with anti-MDA5 antibody-positive dermatomyositis (Case Report)
Lili Jiang, Hong Chen, Lihua Duan
自发性纵隔气肿是抗MDA5皮肌炎的一种相对少见但严重的并发症，增加了其死亡率。本文报道了一名53岁的抗MDA5型皮肌炎患者，其表现为快速进展的间质性肺疾病，尽管进行了积极的免疫抑制治疗，但仍进展为弥漫性皮下气肿和自发性纵隔气肿。经抗感染、适度免疫治疗、持续氧疗等综合治疗，患者反应良好。全面筛查潜在感染，密切监测患者的免疫状态，对于个体化治疗和最大限度改善预后至关重要。
How to cite: Jiang L, Chen H, Duan L. Successful treatment of rapidly progressive interstitial lung disease complicated by a refractory pneumomediastinum in a patient with anti-MDA5 antibody-positive dermatomyositis. Rheumatol Autoimmun 2023; 3: 240-243. doi: 10.1002/rai2.12079
（扫码阅读全文）
Calcinosis cutis in a young man with dermatomyositis (Clinical Image)
Marco Krasselt, Jeanette Henkelmann, Matthias Pierer
本文报告了一名25岁患有多发性肌炎的男性患者。实验室检查显示C-反应蛋白和肌酸激酶升高，抗核抗体、抗Mi-2抗体、抗Jo-1抗体和抗Scl-70抗体阴性，风湿因子阳性。甲襞微循环检查显示大量树状分支的毛细血管，反映了多发性肌炎典型的新生血管形成。体格检查显示上肢、下肢和躯干广泛的皮肤钙质沉着症。患者长期以来仅接受泼尼松治疗，为减少激素副作用，开始使用硫唑嘌呤免疫抑制治疗，但对皮肤钙化无显著改善。文章讨论了多发性肌炎患者罕见的皮肤钙化症状及其治疗挑战。
How to cite: Krasselt M, Henkelmann J, Pierer M. Calcinosis cutis in a young man with dermatomyositis. Rheumatol Autoimmun 2023; 3: 253-254. doi: 10.1002/rai2.12092
（扫码阅读全文）
Combination therapy with methylprednisolone, rituximab, and tofacitinib in antimelanoma differentiation-associated 5 gene dermatomyositis with rapidly progressive interstitial lung disease (Letter)
Mona Manghani, Weiyen Lim, Gin Tsen Chai, Xin Rong Lim, Choon Guan Chua
（扫码阅读全文）
Hypocomplementemic urticarial vasculitis with systemic lupus erythematosus (Letter)
Olfa Frikha, Raida Ben Salah, Mouna Zghal, Naourez Gouiaa, Zouhir Bahloul
How to cite: Frikha O, Ben Salah R, Zghal M, Gouiaa N, Bahloul Z. Hypocomplementemic urticarial vasculitis with systemic lupus erythematosus. Rheumatol Autoimmun 2024; 4: 57-58. doi: 10.1002/rai2.12105.
（扫码阅读全文）
Frailty and antineutrophil cytoplasmic antibody-associated vasculitis: What do we know? (Letter)
Henry H. L. Wu, Nina Brown, Rajkumar Chinnadurai
How to cite: Wu HHL, Brown N, Chinnadurai R. Frailty and antineutrophil cytoplasmic antibody-associated vasculitis: What do we know? Rheumatol Autoimmun 2023; 3: 250-252. doi: 10.1002/rai2.12098.
（扫码阅读全文）
Severe IgA vasculitis with features of remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome in a 60-year-old male treated with plasmapheresis (Case Report)
Shawn Mathew, Rohan Goyal, Nealansh Gupta, Rauno Joks
该病例提示，系统性免疫球蛋白A (IgA)血管炎与缓解型血清阴性对称性滑膜炎伴凹陷水肿综合征(RS3PE综合征)之间可能存在关联。IgA血管炎伴肾脏损害，大剂量糖皮质激素和血浆置换术治疗可缓解。
How to cite: Mathew, S, Goyal, R, Gupta, N, Joks, R. Severe IgA vasculitis with features of remitting seronegative symmetrical synovitis with pitting edema (RS3PE) syndrome in a 60-year-old male treated with plasmapheresis. Rheumatol Autoimmun 2022; 2: 98-101. doi: 10.1002/rai2.12007
（扫码阅读全文）
Rheumatology & Autoimmunity是由中华医学会主办、中华医学杂志社与Wiley合作出版发行的全英文风湿病与免疫学专业期刊，发表风湿病与免疫学领域中临床诊治、转化及基础研究方面的新进展。涵盖风湿病学和免疫学的各个领域，旨在为国内外相关领域科学家与临床专家提供一个学术交流、信息传递的平台，同时提升我国风湿病与免疫学在国际学术界的影响力和竞争力。
期刊发表范围
涵盖风湿病学和临床免疫学的各个领域，包括各种风湿病、自身免疫病以及免疫学基础及转化医学研究。
感兴趣的主题
各种风湿病和自身免疫病的基础和临床研究，包括但不限于以下疾病：
• Rheumatoid Arthritis
类风湿关节炎
• Systemic Lupus Erythematosus
系统性红斑狼疮
• Sjogren Syndrome
干燥综合征
• Spondyloarthritis
脊柱关节炎
• Gout
痛风
• Osteoarthritis
骨关节炎
• Psoriatic Arthritis
银屑病关节炎
• Inflammatory Myopathy
炎性肌病
• Systematic Sclerosis
系统性硬化症
• Systemic Vasculitis
系统性血管炎
