Positions for a postdoctoral researcher
Interested candidates are always encouraged to get in touch with Qi by emailing qi.zhang@adelaide.edu.au. Please include your CV and a cover letter in your email.
Postdoc position #1: Structural Biology
About the project: We are seeking a highly motivated structural biologist to lead projects aiming to understand the structure and function of chromatin-associated complexes involved in gene repression. The candidate will have access to state-of-the-art facilities at Adelaide Microscopy, including multiple transmission electron microscopes (TEM) such as a Glacios 200 kV Cryo-TEM. Additionally, resources available include the Phoenix high-performance computing (HPC), Bragg Crystallography facility, and Adelaide Proteomics Centre. Our collaboration with Monash University further extends our access to advanced 300 kV Titan Krios and Helios 5 UX cryo-FIBSEM.
About you: We are looking for an experienced structural biologist with the following essential and advantageous experiences.
Must have
Extensive biochemistry experience, specifically in expressing and purifying large multi-subunit protein complexes, and analyzing them through in vitro methods.
Extensive experience in structural biology techniques, especially with cryo-EM. This includes sample preparation, data collection, computational analysis, and 3D structure determination of protein macromolecules.
Advantageous (but not required)
Experience in the structural, biochemical, and biophysical study of interactions between DNA/RNA/chromatin and protein.
Experience in cell culture and various molecular biology techniques.
Postdoc position #2: Molecular and Cell Biology
About the project: We are seeking a highly motivated molecular and cell biologist to lead mechanistic studies in epigenetic regulation. The focus of these studies is to understand how chromatin-modifying complexes regulate gene expression and their implications in cancer. The successful candidate will have on-site access to core equipment for epigenetics such as imaging, flow cytometry, NGS sequencer, etc.
About you: We are looking for an experienced molecular and cell biologist with the following essential and advantageous experiences.
Must have
Extensive experience in molecular biology and genomics techniques, particularly in studying transcription and epigenetic regulation using mammalian cell lines. Key techniques include IP, IP-MS, ChIP-seq, ATAC-Seq, CUT&RUN/Tag, RNA-seq, RIP, etc.
Proven experience in genome editing and genomic engineering using mammalian cell lines.
Advantageous (but not required)
Experience in genetic screens, working with stem cells and mouse models, and knowledge of developmental biology and cancer biology.
Skill in coding (R and/or Python) and familiarity with working on Linux-based clusters.
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