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The Multiscale Neurodevelopment Team studies the maturation of cytoarchitecture, connectivity and functional dynamics across early life. Developmental changes are profound and multi-factorial. We aim to use our multiscale frameworks to better understand neurodevelopmental disorders.
Our research program is inspired by working at the interface of microscopy, neuroimaging and computational modelling. We combine post mortem data (histology and transcriptomics) with in vivo imaging (structural and functional MRI, intracranial EEG) to construct multiscale models of the human brain. We hold a special focus on microstructure, as a sort of lynchpin between post mortem and in vivo datasets, and work towards identifying overarching principles of cytoarchitectural organisation, such as the existence of large-scale gradients.
We believe that state-of-the-art neuroanatomy should be incorporated into workflows across neuroscience, from clinical research to building artificial intelligence. To this end, the lab develops tools that support multi-scale approaches in neuroimaging (eg: BigBrainWarp) and we generate standardised atlases of cortical organisation.
We are very grateful for funding from the Deutsche Forschungsgemeinschaft - Emmy Noether Programme, Helmholtz International BigBrain Analytics Labratory, HIBALL and the Klaus Tschira Stiftung.
We’re currently open to applications for PhD and PostDoc positions. If you would like to apply, contact us with your CV and a cover letter.
Contact information
Dr Casey Paquola - c.paquola@fz-juelich.de
Insitute of Neuroscience and Medicine (INM-7)
Research at INM-7 centres on the relationship between the brain and behaviour. Our institute is specialises in integrating multi-modal neuroimaging data and using this information to develop machine learning models for predicting complex phenotypes. The Multiscale Neurodevelopment team is closely tied with the Biomarkers Development group.
Forschungszentrum Jülich
The Forschungszentrum (Research Centre) is a beautiful, leafy campus, that houses domain-expert scientists from across many fields. Additionally, Jülich is only a short train ride to Aachen, Cologne, and Düsseldorf.
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