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会议信息
论坛名称:自然合作会议:2024国际药物研发论坛
会议时间:2024年11月22日
会议地址:北京市昌平区九华山庄会展酒店(16区)3层101、102
指导单位:
北京市昌平区人民政府
北京市科学技术管理委员会、中关村科技园区管理委员会
未来科学城管理委员会(生命园管委会)
北京市昌平区科学技术委员会
主办单位:
北京中关村生命科学园发展有限责任公司
Nature-Portfolio
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会议议程
出席大咖
罗敏敏
罗敏敏于1995年从北京大学毕业,之后赴美国留学;1997年获得美国宾夕法尼亚大学计算机科学硕士学位;2000年获得宾夕法尼亚大学神经学博士学位;2000年至2004年在杜克大学神经生物学系从事博士后研究工作;2004年回到中国后长期在北京生命科学研究所担任研究员;2005年获得国家杰出青年科学基金资助;2018年兼任北京脑科学与类脑研究所所长;2023年获得首期新基石研究员项目资助。
LUO Minmin
Born Jiangxi Province, LUO Minmin is a neurobiologist and serves as the Director of the Chinese Institute for Brain Research, Beijing (CIBR) and a New Cornerstone Investigator. He graduated with a BS degree in psychology from Peking University in 1995 and then went to the United States for further studies; he obtained a Master's degree in Computer Science from the University of Pennsylvania in 1997 and a Ph.D. in Neuroscience from the same university in 2000. From 2000 to 2004, he conducted postdoctoral research at HHMI and the Department of Neurobiology at Duke University. After returning to China in 2004, he has long served as an Investigator at the National Institute of Biological Sciences, Beijing. In 2005, he was awarded funding from the National Natural Science Fund for Distinguished Young Scholars. In 2018, he took on the additional role of Director of CIBR.
Adil Mardinoglu
Adil Mardinoglu 教授是英国伦敦国王学院宿主与微生物组相互作用中心和瑞典皇家理工学院生命科学实验室(SciLifeLab)的系统生物学教授。Mardinoglu 教授领导着一个由30余人组成的研究团队,将多组学、系统生物学、人工智能和实验生物学与药物开发相结合,领导开发针对代谢性疾病、神经退行性疾病以及某些癌症的新型治疗策略。
Adil Mardinoglu Bio
Professor Adil Mardinoglu works as a Professor of Systems Biology at the Centre for Host-Microbiome Interactions at King’s College London, UK, and Science for Life Laboratory (SciLifeLab) at KTH-Royal Institute of Technology in Sweden. At the helm of a 30-strong research team, Professor Mardinoglu spearheads the development of novel treatment strategies for metabolic and neurodegenerative diseases, as well as certain cancers, blending multiomics, systems biology, AI and experimental biology with drug development.
A key contributor to the Swedish Human Protein Atlas program, Professor Mardinoglu has aided in the construction of a comprehensive human tissue, subcellular, and pathology atlas, and he has been instrumental in developing the cell atlas within the international Human Cell Atlas initiative. His scholarly output includes around more than 250 research and review articles published in journals such as Science, Nature, Nature Biotechnology, Cell Metabolism, Nature Metabolism, Nature Communications, PNAS, Cell Reports, Molecular Systems Biology, and EbioMedicine. Furthermore, as a co-founder of SZA Longevity, BASH Biotech, ScandiBio Therapeutics, ScandiEdge Therapeutics, and Trustlife Therapeutics, he has made substantial entrepreneurial contributions to the biotech sector.
帅克
天汇资本原创新药投资首席科学家
帅克教授于1990年在美国艾伯特爱因斯坦医学院(Albert Einstein College of Medicine)取得博士学位,随即进入美国洛克菲勒大学师从世界著名的荣获美国总统科学奖章的James E. Darnell教授实验室进行博士后研究。1994年入职美国加州大学洛杉矶分校(UCLA),并于2004年成为UCLA终身正教授。2021年7月,帅克教授辞去其长期任教的UCLA终身正教授职位,全职加盟南京大学现代生物研究院。
Ke Shuai, Ph.D.
Full Professor with Tenure at the Institute of Modern Biology, Nanjing University
Overseas High-Level Talent of the National Innovation Long-Term Program
Professor Emeritus at the University of California, Los Angeles (UCLA)
Chief Scientist of Innovative Drug Investment at Tianhui Capital
Professor Shuai obtained his Ph.D. in 1990 from the Albert Einstein College of Medicine in the United States. He then began his postdoctoral research at Rockefeller University, working in the lab of Professor James E. Darnell, a world-renowned scientist and recipient of the U.S. Presidential Science Medal. In 1994, Professor Shuai joined the University of California, Los Angeles (UCLA), and in 2004, he became a full professor with tenure at UCLA. In July 2021, he resigned from his long-held tenured position at UCLA to join the Institute of Modern Biology at Nanjing University full-time.
Professor Shuai is one of the primary discoverers of the JAK-STAT signaling pathway. He was the first in the world to identify that an important protein in interferon signaling is a transcription factor with specific DNA recognition functions (Shuai et al., 1992, Science), which was later named as STAT (Signal Transducer and Activator of Transcription) (Shuai et al., 1993, Science), and the STAT/JAK signaling pathway (Shuai et al., 1993, Nature; Shuai et al., 1994, Cell). His laboratory was the first to discover and name the PIAS (Protein Inhibitor of Activated STAT) family of proteins (Chung et al., 1997, Science; Liu et al., 2007, Cell; Liu et al., 2010, Science), demonstrating that PIAS proteins are key regulators of STATs. These groundbreaking discoveries have provided new avenues for clinical treatment and drug development. Professor Shuai's research has been published in leading international journals such as Cell, Nature, and Science. In recent years, innovative drugs targeting the JAK-STAT signaling pathway have been widely used to treat various autoimmune diseases. JAK inhibitors have shown promising results in Phase II clinical trials for tumor immunotherapy. A patent on JAK-STAT signaling, with Professor Shuai as one of the inventors, was successfully used in the development of the drug Promacta (Eltrombopag) for treating aplastic anemia. Novartis' Promacta had annual sales exceeding $2 billion in 2021.
Minoru Takasato 博士
理化学研究所生物系统动力学研究中心团队负责人
Minoru Takasato Ph.D.
Team leader at RIKEN BDR, Kobe Japan
Dr. Minoru Takasato is an expert in the directed differentiation of human pluripotent stem cells into kidneys. His laboratory focuses on reproducing the process of human organogenesis, using human pluripotent stem cells to generate organoids. In Nature, Published multiple papers in high-level journals such as Nature Methods, Nature Communications, Nature Cell Biology, Cell Stem Cell, et.
张曼博士
Dr. Man (Maya) Zhang
joined Insilico Medicine in 2022 as VP, Head of biology and translational medicine, leading discovery biology and translational medical research. Dr. Zhang has more than 15 years’ working experience in pharmaceutical and biotechnology companies. In 2008 to 2016, Dr. Zhang worked as a function and project leader at Novartis Shanghai site, leading multiple oncology, chronical liver diseases discovery projects. She then joined Hepatitis B DAS in Janssen Shanghai Discovery Center, leading multiple anti-hepatitis B discovery projects. In Hengrui Pharmaceutical, she has established a translational medicine team to support early clinical development of multiple assets including IND enabling, biomarker discovery, indication expansion and drug combination etc. Dr. Zhang obtained Bachelor of Science and Master of Science from the School of Life Sciences of Peking University, China and PhD from the University of Texas at Austin, USA.
Bernd Wollscheid
Bernd Wollscheid博士是DISCO Pharmaceutical的创始人。他同时是瑞士苏黎世联邦理工学院分子健康教授及转化医学研究所所长。他担任ETH领域战略重点项目“个性化健康与相关技术(PHRT)”的执行委员会主席,致力于将科学发现应用于医疗保健实践。Bernd的研究团队在生物学、化学、医学和生物信息学交叉领域,率先开发并应用下一代技术。这些研究有助于理解分子纳米级结构如何影响细胞功能,并为治疗性诊断开辟了新机遇。
Bernd曾在德国弗莱堡马克斯-普朗克免疫生物学研究所学习化学,并获得分子免疫学博士学位。他曾在美国西雅图系统生物学研究所从事博士后研究。
Bernd Wollscheid
Bernd Wollscheid, Ph.D., is founder of DISCO Pharmaceuticals. He is a Professor of Molecular Health and Head of the Institute of Translational Medicine at the Department of Health Sciences and Technology at ETH Zürich, Switzerland. As the chairman of EC of the ETH domain Strategic Focus Area, “Personalized Health and Related Technology (PHRT),” he aims to bridge the gap between scientific discoveries and their practical applications in healthcare. Bernd’s research team pioneers developing and applying next-generation technologies at the intersection of biology, chemistry, medicine, and bioinformatics. This research contributes to understanding how molecular nanoscale organization influences cellular function and opens up new opportunities for theranostics.
Bernd studied Chemistry and holds a Ph.D. in Molecular Immunology from the Max Planck Institute of Immunobiology in Freiburg, Germany. He performed post-doctoral research at the Institute of Systems Biology, Seattle, USA.
王军
王军,理学博士
中国科学院微生物研究所,中科院免疫与病原微生物重点实验室
德国马普学会合作伙伴小组-生物信息学与计算生物学研究组长,研究员
主要研究方向: 生物信息学和计算生物学分析;微生物大数据的比较和挖掘;新测序方法和人工智能方法的应用。
人体微生物组是指人体内由微生物组成的共生生态群落。近年来,人体微生物组受到生命科学和医学研究领域的高度关注,复杂的微生物组参与人体各系统生理功能,而菌群异常可导致多种疾病,包括感染、代谢性疾病以及自身免疫疾病等。申请人关注微生物组研究领域的核心问题——如何高效、准确鉴定和利用微生物组中影响人类健康与疾病的关键类群以及作用分子,主要研究成果包括:1)在感染性疾病研究中,建立了快速而精准的靶向RNA的病原检测方法;使用人工智能方法高通量发现了一系列微生物源新型抗菌多肽,用于耐药病原的治疗。2)在代谢相关研究中,结合三代测序产生的长读长序列信息,在菌株水平实现对微生物组代谢潜力的精细解析;通过对人体和模式动物肠道菌群节律的研究,发现并验证了影响宿主肠道节律和代谢的关键氨基酸。3)在自身免疫性疾病研究中,通过临床合作,发现了在免疫失调中微生物组发挥作用的关键“致病”蛋白组分,以及能够有效抑制自身免疫反应的微生物源“治病”蛋白成分。
Wang Jun, PhD in Science
Institute of Microbiology, Chinese Academy of Sciences, Key Laboratory of Immunology and Pathogenic Microorganisms, Chinese Academy of Sciences.
German Max Planck Society Partner Group - Bioinformatics and Computational Biology Research Leader, Researcher.
Main research areas: Bioinformatics and Computational Biology Analysis; Comparison and mining of microbial big data; The application of new sequencing methods and artificial intelligence methods.
The human microbiome refers to the symbiotic ecological community composed of microorganisms within the human body. In recent years, the human microbiome has received high attention in the fields of life sciences and medical research. The complex microbiome is involved in the physiological functions of various systems in the human body, and abnormal microbiota can lead to various diseases, including infections, metabolic diseases, and autoimmune diseases. The applicant pays attention to the core issue in the field of microbiome research - how to identify and use the key groups and action molecules in the microbiome that affect human health and disease efficiently and accurately. The main research achievements include: 1) In the research of infectious diseases, a rapid and accurate method for pathogen detection targeting RNA has been established; A series of novel antimicrobial peptides derived from microorganisms have been discovered through high-throughput artificial intelligence methods for the treatment of drug-resistant pathogens. 2) In metabolic related research, combining the long read long sequence information generated by third-generation sequencing, fine analysis of microbial metabolic potential can be achieved at the strain level; Through the study of gut microbiota rhythms in humans and model animals, key amino acids that affect host gut rhythms and metabolism have been identified and validated. 3) In the study of autoimmune diseases, through clinical collaboration, key "pathogenic" protein components that play a role in the microbiome in immune disorders have been discovered, as well as microbial derived "therapeutic" protein components that can effectively inhibit autoimmune responses.
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参会报名
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参会、合作咨询
来源 | 中关村生命科学园(药智网获取授权转载)
责任编辑 | 马雪莲
商务合作 | 王存星 19922864877(同微信)
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