Cell Transplantation 作为再生医学领域享有盛誉的基石期刊,自32年前由Dr. Camillo Ricordi和Dr. Paul R. Sanberg创立以来,一直走在科研的最前沿。现在,随着新篇章的开启,我们向卸任的共同主编Paul R. Sanberg和Shinn-Zong Lin致以崇高的敬意,感谢他们引领期刊到达目前的科学高峰。今后,他们将以名誉共同主编的身份继续贡献他们的智慧和经验。
2024年,Cell Transplantation 期刊在2019至2022年间发表的一些文章被撤回,这是为了维护科学研究的诚信和读者的信任。虽然这对于期刊团队和出版方是一个艰难的决定,但为了确保其出版物不仅具备开创性,而且数据可靠和在科学上合理,这是必要的。
随着细胞移植技术在治疗多种疾病方面的潜力日益显现,Cell Transplantation期刊也将迈入一个新时代。干细胞生物学、组织工程和免疫学等的进步,都促进了细胞移植领域的迅速发展。Cell Transplantation 期刊必须反映这些发展,并提供当前研究状态的全面概述。
从2025年起,Cell Transplantation 将采用更严格的科学标准。这一决定经过深思熟虑,是对细胞移植研究不断演变的响应。目标是确保该期刊保持在科学发现的前沿,并继续成为参考高质量、尖端的细胞移植及其应用研究的可靠来源。
Cell Transplantation 期刊将更专注于发表细胞移植及其应用的机制研究或功能分析,而不是将细胞移植仅作为实验过程中使用的方法的研究。其考虑发表的主题包括但不限于:
1. 干细胞研究与治疗:涉及干细胞的分离、特征和治疗应用,包括胚胎干细胞、成体干细胞和诱导多能干细胞。
Featured Article
Quintero Sierra LA, Biswas R, Conti A, et al. Highly Pluripotent Adipose-Derived Stem Cell–Enriched Nanofat: A Novel Translational System in Stem Cell Therapy. Cell Transplantation. 2023;32. doi:10.1177/09636897231175968
Wu J-X, Xia T, She L-P, Lin S, Luo X-M. Stem Cell Therapies for Human Infertility: Advantages and Challenges. Cell Transplantation. 2022;31. doi:10.1177/09636897221083252
2. 异种移植研究:研究不同物种间细胞、组织或器官的移植,包括异种移植排斥、兼容性和克服免疫屏障的策略。
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Arabi TZ, Sabbah BN, Lerman A, Zhu X-Y, Lerman LO. Xenotransplantation: Current Challenges and Emerging Solutions. Cell Transplantation. 2023;32. doi:10.1177/09636897221148771
O’Neill A, Martinez AL, Mueller AL, et al. Optimization of Xenografting Methods for Generating Human Skeletal Muscle in Mice. Cell Transplantation. 2024;33. doi:10.1177/09636897241242624
3. 细胞分化和重编程:研究细胞分化、谱系分化和体细胞重编程为多能性。
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Hu K, Jin S, Yue K, et al. A Reversible Neural Stem Cell Quiescence and Activation Culture System for Metabolic Study. Cell Transplantation. 2024;33. doi:10.1177/09636897241259723
4. 组织工程和再生医学:研究开发生物材料、支架和生物工程化组织用于再生疗法。
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Hu L, Zhou J, He Z, et al. In Situ-Formed Fibrin Hydrogel Scaffold Loaded With Human Umbilical Cord Mesenchymal Stem Cells Promotes Skin Wound Healing. Cell Transplantation. 2023;32. doi:10.1177/09636897231156215
Kanda M, Nagai T, Kondo N, et al. Pericardial Grafting of Cardiac Progenitor Cells in Self-Assembling Peptide Scaffold Improves Cardiac Function After Myocardial Infarction. Cell Transplantation. 2023;32. doi:10.1177/09636897231174078
Khayatan D, Bagherzadeh Oskouei A, Alam M, et al. Cross Talk Between Cells and the Current Bioceramics in Bone Regeneration: A Comprehensive Review. Cell Transplantation. 2024;33. doi:10.1177/09636897241236030
5. 免疫学和移植耐受性:研究对移植细胞的免疫反应,发展诱导耐受性的策略。
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Chen R, Zhao H, Ai L, Zhang J, Jiang D. Inhibiting T-Cell-Mediated Rejection of the Porcine Meniscus Through Freeze-Thawing and Downregulating Porcine Xenoreactive Antigen Genes. Cell Transplantation. 2024;33. doi:10.1177/09636897241273689
6. 基因治疗和基因修饰:研究使用基因工程技术优化细胞以用于治疗目的。
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Nakajima I, Tsukimura T, Ono T, et al. In Vivo Delivery of Therapeutic Molecules by Transplantation of Genome-Edited Induced Pluripotent Stem Cells. Cell Transplantation. 2023;32. doi:10.1177/09636897231173734
7. 神经性疾病的细胞治疗:临床和临床前研究使用细胞移植治疗神经性疾病。
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Li M, Li J, Chen H, Zhu M. VEGF-Expressing Mesenchymal Stem Cell Therapy for Safe and Effective Treatment of Pain in Parkinson’s Disease. Cell Transplantation. 2023;32. doi:10.1177/09636897221149130
Hastings N, Kuan W-L, Osborne A, Kotter MRN. Therapeutic Potential of Astrocyte Transplantation. Cell Transplantation. 2022;31. doi:10.1177/09636897221105499
Nabetani M, Mukai T, Taguchi A. Cell Therapies for Autism Spectrum Disorder Based on New Pathophysiology: A Review. Cell Transplantation. 2023;32. doi:10.1177/09636897231163217
8. 癌症的细胞移植:研究在癌症免疫疗法中使用免疫细胞,如CAR-T细胞。
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Han J, Zhang B, Zheng S, Jiang Y, Zhang X, Mao K. The Progress and Prospects of Immune Cell Therapy for the Treatment of Cancer. Cell Transplantation. 2024;33. doi:10.1177/09636897241231892
Li Q, Lyu C, Liu M, et al. Donor Hematopoietic Stem Cell/Lymphocyte Maintenance Treatment After CAR T-Cell Therapy in Patients With B-Cell Acute Lymphoblastic Leukemia Relapse Following Stem Cell Transplant. Cell Transplantation. 2023;32. doi:10.1177/09636897231158155
9. 心血管细胞移植:研究使用细胞疗法修复心脏,包括治疗心肌梗死和心力衰竭。
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Maeda S, Kawamura T, Chida D, et al. Notch Signaling-Modified Mesenchymal Stem Cell Patch Improves Left Ventricular Function via Arteriogenesis Induction in a Rat Myocardial Infarction Model. Cell Transplantation. 2023;32. doi:10.1177/09636897231154580
10. 代谢性疾病的细胞移植:研究基于细胞的糖尿病、肝病等代谢性疾病治疗。
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Lemos JRN, Baidal DA, Poggioli R, et al. HLA-B Matching Prolongs Allograft Survival in Islet Cell Transplantation. Cell Transplantation. 2023;32. doi:10.1177/09636897231166529
Yamasaki M, Maki T, Mochida T, et al. Xenogenic Engraftment of Human-Induced Pluripotent Stem Cell–Derived Pancreatic Islet Cells in an Immunosuppressive Diabetic Göttingen Mini-Pig Model. Cell Transplantation. 2024;33. doi:10.1177/09636897241288932
Yamada S, Yukawa H, Kitamura K, et al. In Vivo Real-Time Quantum Dots Imaging to Track Transplanted Adipose Stem Cells in Different Inflammatory States of Acute Liver Failure Mice. Cell Transplantation. 2023;32. doi:10.1177/09636897231176442
Udagawa D, Nagata S, Yagi H, et al. A Novel Approach to Orthotopic Hepatocyte Transplantation Engineered With Liver Hydrogel for Fibrotic Livers, Enhancing Cell–Cell Interaction and Angiogenesis. Cell Transplantation. 2024;33. doi:10.1177/09636897241253700
11. 伦理、法律和社会影响(ELSI):讨论和分析细胞移植的伦理、法律和社会影响等方面。
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Strell P, Shetty A, Steer CJ, Low WC. Interspecies Chimeric Barriers for Generating Exogenic Organs and Cells for Transplantation. Cell Transplantation. 2022;31. doi:10.1177/09636897221110525
Brown JL, Voth JP, Person K, Low WC. A Technological and Regulatory Review on Human–Animal Chimera Research: The Current Landscape of Biology, Law, and Public Opinion. Cell Transplantation. 2023;32. doi:10.1177/09636897231183112
12. 临床试验和结果:涉及细胞移植的临床试验结果报道。
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de Celis-Ruiz E, Fuentes B, Alonso de Leciñana M, et al. Final Results of Allogeneic Adipose Tissue–Derived Mesenchymal Stem Cells in Acute Ischemic Stroke (AMASCIS): A Phase II, Randomized, Double-Blind, Placebo-Controlled, Single-Center, Pilot Clinical Trial. Cell Transplantation. 2022;31. doi:10.1177/09636897221083863
Yamashita T, Nakano Y, Sasaki R, et al. Safety and Clinical Effects of a Muse Cell-Based Product in Patients With Amyotrophic Lateral Sclerosis: Results of a Phase 2 Clinical Trial. Cell Transplantation. 2023;32. doi:10.1177/09636897231214370
13. 细胞移植的技术革新:细胞分离、培养、扩增和移植技术的发展。
Featured Article
Gonzalez N, Kato H, Tixi W, et al. Ubiquitous Luciferase Expression in “Firefly Rats” Does Not Alter the Pancreatic Islet Morphology, Metabolism, and Function. Cell Transplantation. 2023;32. doi:10.1177/09636897231182497
14. 临床前模型和动物研究:使用动物模型研究细胞移植疗法的疗效和机制。
Featured Article
Scholz J, Secreto FJ, Wobig J, et al. Human Stem Cell–Derived Cardiomyocytes Integrate Into the Heart of Monkeys With Right Ventricular Pressure Overload. Cell Transplantation. 2024;33. doi:10.1177/09636897241290367
Kobayashi Y, Shigyo M, Platoshyn O, et al. Expandable Sendai-Virus-Reprogrammed Human iPSC-Neuronal Precursors: In Vivo Post-Grafting Safety Characterization in Rats and Adult Pig. Cell Transplantation. 2023;32. doi:10.1177/09636897221107009
15.罕见疾病的细胞移植:专注于罕见或孤儿疾病的细胞治疗应用研究。
今后,Cell Transplantation 期刊将提高科学标准,加强同行评审过程,确保发表严格和有高影响力的研究成果。这包括实施额外的数据完整性的检查,监测在提交和同行评审过程中的不寻常活动,邀请具有对应学术背景且合适资质的审稿人。
Cell Transplantation 致力于以学术诚信和科学严谨推进细胞移植基础研究和其转化应用及临床医学领域。感谢前任主编们的贡献,并期待学术界的持续支持。Cell Transplantation 团队诚邀全球的科研工作者将他们的创新研究成果提交给Cell Transplantation,共同推动细胞移植领域的进步。Cell Transplantation将提供一个卓越的学术交流平台,让来自不同学科的研究人员能够汇聚一堂,分享知识,激发灵感,最终为细胞移植疗法的发展贡献力量。
--携手前行,在诚信和严谨的科学精神指引下,揭开细胞移植研究的新篇章--