写在前面的话
新兴技术愈发兴旺，如何落地实现科研转化呢？通过整理单细胞转录组的应用文章，以时间为序，细细品味单细胞技术应用的发展进展，总结技术路线最直接呈现文章核心部分，这个系列持续更新，以10篇文章为一期！！！会发现读文献是一种快乐~
督促看文献，坚持！
Molecular Subgroups of Intrahepatic Cholangiocarcinoma Discovered by Single-Cell RNA Sequencing-Assisted Multiomics Analysis (Cancer immunology research)
Differential metabolic requirement governed by transcription factor c-Maf dictates innate γδT17 effector functionality in mice and humans (Science advances)
A single-cell transcriptomic atlas characterizes the silk-producing organ in the silkworm (Nature communication)
A mechanosensitive lipolytic factor in the bone marrow promotes osteogenesis and lymphopoiesis (Cell metabolism)
Cleavage of tropomodulin-3 by asparagine endopeptidase promotes cancer malignancy by actin remodeling and SND1/RhoA signaling (Journal of experimental & clinical cancer research)
Epg5 deficiency leads to primary ovarian insufficiency due to WT1 accumulation in mouse granulosa cells (Autophagy)
Single-cell atlas of keratoconus corneas revealed aberrant transcriptional signatures and implicated mechanical stretch as a trigger for keratoconus pathogenesis (Cell discovery)
Single-cell multiomics analysis reveals regulatory programs in clear cell renal cell carcinoma (Cell discovery)
Renewal of embryonic and neonatal-derived cardiac-resident macrophages in response to environmental cues abrogated their potential to promote cardiomyocyte proliferation via Jagged-1-Notch1 (Acta pharmaceutica sinica B)
VG161 activates systemic antitumor immunity in pancreatic cancer models as a novel oncolytic herpesvirus expressing multiple immunomodulatory transgenes (Journal of medical virology)
