写在前面的话
新兴技术愈发兴旺,如何落地实现科研转化呢?通过整理单细胞转录组的应用文章,以时间为序,细细品味单细胞技术应用的发展进展,总结技术路线最直接呈现文章核心部分,这个系列持续更新,以10篇文章为一期!!!会发现读文献是一种快乐~
督促看文献,坚持!
Dissecting the single-cell transcriptome network underlying esophagus non-malignant tissues and esophageal squamous cell carcinoma (EbioMedicine)
Topological analysis of hepatocellular carcinoma tumour microenvironment based on imaging mass cytometry reveals cellular neighbourhood regulated reversely by macrophages with different ontogeny (Gut)
Single-cell transcriptomes reveal heterogeneity of high-grade serous ovarian carcinoma (Clinical and translational medicine)
Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells (Theranostics)
The histone demethylase Kdm6b regulates the maturation and cytotoxicity of TCRαβ+CD8αα+ intestinal intraepithelial lymphocytes (Cell Death & Differentiation)
5mC regulator-mediated molecular subtypes depict the hallmarks of the tumor microenvironment and guide precision medicine in bladder cancer (BMC medicine)
Stroke subtype-dependent synapse elimination by reactive gliosis in mice (Nature Communication)
Single-cell RNA-seq and chromatin accessibility profiling decipher the heterogeneity of mouse γδ T cells (Science Bulletin)
Single-cell RNA sequencing reveals B cell-related molecular biomarkers for Alzheimer's disease (Experimental & Molecular Medicine)
From nasal to basal: single-cell sequencing of the bursa of Fabricius highlights the IBDV infection mechanism in chickens (Cell & Bioscience)