职位信息
PhD Student Position in Stomata Biology and Starch Metabolism
12月20日
Stomata are microscopic pores on the leaf epidermis surrounded by a pair of guard cells. Stomata open and close in response to environmental stimuli to facilitate gas exchange between the plant and the atmosphere. Plants with fast stomatal movements adapt more quickly to changes in their environment and show increased stress tolerance and productivity.
Research in the Santelia group demonstrated that guard cell starch metabolism is one of the key factors for fast stomatal movements. Our research focuses on understanding the molecular mechanisms underpinning fast stomatal movements through the regulation of guard cell starch turnover.
We discovered that in Arabidopsis thaliana, the glucan hydrolase beta-amylase 1 (BAM1) is a major player in rapid guard cell starch degradation in response to blue light - a stimulus inducing fast stomatal opening; while its closest homolog BAM3, is involved in stomatal responses during pathogen attack.
This position offers an exciting opportunity to explore the evolution and subfunctionalization of BAM1 and BAM3 in plants and how they contribute to plant productivity and stress resilience by regulating starch dynamics in guard cells.
Research Focus:
Reconstruct the evolutionary history and phylogeny of BAM1 and BAM3 in plants
Investigate the role of BAM1 and BAM3 from divergent plant lineages in stomatal responses to blue light and pathogens
Create chimera proteins and clone BAM1 and BAM3 from divergent land plant lineages for complementation studies in Arabidopsis bam1 and bam3 mutants
Perform RNA sequencing (RNAseq) in guard cells in response to blue light of Arabidopsis accessions with divergent stomatal responses to blue light and varying blue light-induced starch turnover. Molecular genetics analyses of newly identified genes
A Master’s degree in plant biology, Molecular Biology, Biochemistry, or a related field
Strong background in plant physiology and molecular biology techniques
Experience with RNAseq, gene cloning, and Arabidopsis genetics is highly desirable
Excellent communication and teamwork skills
English proficiency
Conduct independent research under the supervision of senior researchers
Design and perform experiments, analyse data, and interpret results
Prepare and present research findings at scientific conferences and in peer-reviewed journals
Collaborate with other team members and contribute to the overall research goals
https://jobs.ethz.ch/job/view/JOPG_ethz_p8lsdN38abbSqslY1s
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号主简介
@留德华叫兽：系美国Clemson大学数学硕士(运筹学方向)、Ph.D. candidate，欧盟玛丽居里学者，德国海德堡大学数学博士(离散优化、图像处理)，读博期间前往意大利博洛尼亚大学、IBM实习半年，巴黎综合理工访问一季。现任德国无人驾驶资深研发工程师。
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