【罂粟摘要】鼻骨骨折全麻和局麻治疗结果的比较:荟萃分析

文摘   2024-11-07 07:01   贵州  

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鼻骨骨折全麻和局麻治疗结果的比较:荟萃分析


贵州医科大学  麻醉与心脏电生理课题组

翻译:柏雪  编辑:王婷婷  审校:曹莹

背景:本荟萃分析旨在对全身麻醉(GA)和局部麻醉(LA)在鼻骨骨折(NBFs)患者治疗中的作用进行全面比较。


方法:综合检索PubMed、Embase、Web of Science。研究调查了GA和LA在NBFs治疗中的临床结果。计算合并优势比(OR)和各自的95%置信区间(CIs)。评估纳入研究之间的异质性。对纳入研究的偏倚风险进行评估。


结果:本荟萃分析共纳入8项研究。美容结果、鼻中隔残留畸形、是否需要进一步手术、患者对麻醉过程的满意度和患者对手术结果的满意度的总ORs值为0.70 (95% CI 0.18, 2.64z =−0.53,p = 0.5957), 1.11 (95% CI 0.37, 3.30; z = 0.18, p = 0.8558), 1.19 (95% CI 0.65, 2.20z = 0.56, p = 0.5760), 1.57 (95% CI 0.92, 2.69z = 1.65,p =0.0982) 1.00 (95% CI 0.55, 1.80z =−0.00, p = 0.9974)



结论:GA与LA手法治疗NBFs患者的临床疗效差异无统计学意义,麻醉入路的选择应根据方法的耐受性和鼻骨折的严重程度来考虑。

原始文献来源:Ting Xu1, Xinsheng Yi, Shitong Xia and Sihai Wu. Comparison of outcomes for general and local anesthesia in the management of nasal bone fractures: a meta-analysis. European Journal of Medical Research (2024) 29:306


Comparison of outcomes for general and local anesthesia in the management of nasal bone fractures: a meta-analysis

Background This meta-analysis aimed to perform a head-to-head comparison of the role of general anesthesia (GA) and local anesthesia (LA) in the management of patients with nasal bone fractures (NBFs).
Methods PubMed, Embase, and Web of Science were comprehensively searched. Studies investigating the clinical outcomes of GA and LA in the management of NBFs were included. Pooled odds ratios (OR) with the respective 95% confidence intervals (CIs) were calculated. Heterogeneity between the included studies was evaluated. The risk of bias in the included studies was assessed.
Results Eight studies were included in this meta-analysis. The pooled ORs for cosmetic results, residual septal deformity, the need for further surgery, patients’ satisfaction with the anesthesia procedure, and patients’ satisfaction with the surgery results were 0.70 (95% CI 0.18, 2.64; z = − 0.53, p = 0.5957), 1.11 (95% CI 0.37, 3.30; z = 0.18, p = 0.8558), 1.19 (95% CI 0.65, 2.20; z = 0.56, p = 0.5760), 1.57 (95% CI 0.92, 2.69; z = 1.65, p = 0.0982), and 1.00 (95% CI 0.55, 1.80; z = − 0.00, p = 0.9974).
Conclusions Insignificant difference on clinical outcomes was observed between GA and LA in the manipulation of patients with NBFs, and the choice of anesthetic approach should be based on the tolerability of the methods and the severity of nasal fractures.
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